The regulatory landscape of retinoblastoma: a pathway analysis perspective.

Autor: Gómez-Romero L; Computational Genomics Division, National Institute of Genomic Medicine (INMEGEN), Mexico City, Mexico., Alvarez-Suarez DE; Medical Research Unit in Infectious Diseases, Hospital de Pediatría, CMN SXXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.; Pharmacology Department, CINVESTAV, Mexico City, Mexico., Hernández-Lemus E; Computational Genomics Division, National Institute of Genomic Medicine (INMEGEN), Mexico City, Mexico.; Center for Complexity Sciences, National Autonomous University of Mexico (UNAM), Mexico City, Mexico., Ponce-Castañeda MV; Medical Research Unit in Infectious Diseases, Hospital de Pediatría, CMN SXXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Tovar H; Computational Genomics Division, National Institute of Genomic Medicine (INMEGEN), Mexico City, Mexico.

Publikováno v: Royal Society open science [R Soc Open Sci] 2022 May 18; Vol. 9 (5), pp. 220031. Date of Electronic Publication: 2022 May 18 (Print Publication: 2022).

Circulating miRNome detection analysis reveals 537 miRNAS in plasma, 625 in extracellular vesicles and a discriminant plasma signature of 19 miRNAs in children with retinoblastoma from which 14 are also detected in corresponding primary tumors.

Autor: Castro-Magdonel BE; Medical Research Unit in Infectious Diseases, Hospital de Pediatría, CMN SXXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Orjuela M; Epidemiology Department, Columbia University, New York, New York, United States of America., Alvarez-Suarez DE; Medical Research Unit in Infectious Diseases, Hospital de Pediatría, CMN SXXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.; Pharmacology Department, CINVESTAV, Mexico City, Mexico., Camacho J; Pharmacology Department, CINVESTAV, Mexico City, Mexico., Cabrera-Muñoz L; Pathology Department, Hospital Infantil de Mexico Federico Gómez, Secretaría de Salud, Mexico City, Mexico., Sadowinski-Pine S; Pathology Department, Hospital Infantil de Mexico Federico Gómez, Secretaría de Salud, Mexico City, Mexico., Medina-Sanson A; Oncology Department, Hospital Infantil de México Federico Gómez, Secretaría de Salud, Mexico City, Mexico., Lara-Molina C; Ophtalmology Department, Hospital Infantil de Mexico Federico Gómez, Secretaría de Salud, Mexico City, Mexico., García-Vega D; Ophtalmology Department, Hospital de Pediatría Silvestre Frenk, CMN SXXI, IMSS, Mexico City, Mexico., Vázquez Y; Ophtalmology Department, Hospital de Pediatría Silvestre Frenk, CMN SXXI, IMSS, Mexico City, Mexico., Durán-Figueroa N; Unidad Profesional Interdisciplinaria de Biotecnología, Instituto Politécnico Nacional, Mexico City, Mexico., Orozco-Romero MJ; Unidad Profesional Interdisciplinaria de Biotecnología, Instituto Politécnico Nacional, Mexico City, Mexico., Hernández-Ángeles A; Medical Research Unit in Infectious Diseases, Hospital de Pediatría, CMN SXXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Ponce-Castañeda MV; Medical Research Unit in Infectious Diseases, Hospital de Pediatría, CMN SXXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.

Publikováno v: PloS one [PLoS One] 2020 Apr 14; Vol. 15 (4), pp. e0231394. Date of Electronic Publication: 2020 Apr 14 (Print Publication: 2020).