Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Alvarez Laviada, A"'
Autor:
Williams, Zachary J., Alvarez-Laviada, Anita, Hoagland, Daniel, Jourdan, L. Jane, Poelzing, Steven, Gorelik, Julia, Gourdie, Robert G.
Publikováno v:
In Journal of Molecular and Cellular Cardiology September 2024 194:32-45
Autor:
Qianqian Song, Anita Alvarez-Laviada, Sarah E. Schrup, Benedict Reilly-O’Donnell, Emilia Entcheva, Julia Gorelik
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract We present a novel framework, Opto-SICM, for studies of cellular interactions in live cells with high spatiotemporal resolution. The approach combines scanning ion conductance microscopy, SICM, and cell-type-specific optogenetic interrogatio
Externí odkaz:
https://doaj.org/article/b4bc18664cbd4e28900c83e810883c69
Autor:
Song, Qianqian1 (AUTHOR), Alvarez-Laviada, Anita1 (AUTHOR), Schrup, Sarah E.2 (AUTHOR), Reilly-O'Donnell, Benedict1 (AUTHOR), Entcheva, Emilia2 (AUTHOR) entcheva@gwu.edu, Gorelik, Julia1 (AUTHOR) j.gorelik@imperial.ac.uk
Publikováno v:
Communications Biology. 11/8/2023, Vol. 6 Issue 1, p1-11. 11p.
Autor:
Alvarez Laviada, A.
Voltage-gated calcium (Cav) channels are essential components of excitable cells. The function of neurons is highly dependent on the plasma membrane availability of Cav channels, which allow entry of Ca2+. Cav channels control a variety of processes,
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625770
Autor:
Peter T. Wright, Navneet K. Bhogal, Ivan Diakonov, Laura M.K. Pannell, Ruwan K. Perera, Nadja I. Bork, Sophie Schobesberger, Carla Lucarelli, Giuseppe Faggian, Anita Alvarez-Laviada, Manuela Zaccolo, Timothy J. Kamp, Ravi C. Balijepalli, Alexander R. Lyon, Sian E. Harding, Viacheslav O. Nikolaev, Julia Gorelik
Publikováno v:
Cell Reports, Vol 23, Iss 2, Pp 459-469 (2018)
Summary: Cardiomyocytes from the apex but not the base of the heart increase their contractility in response to β2-adrenoceptor (β2AR) stimulation, which may underlie the development of Takotsubo cardiomyopathy. However, both cell types produce com
Externí odkaz:
https://doaj.org/article/9fb32f6b27744542b14dddf7b8ced575
Autor:
Peter T. Wright, Jose L. Sanchez-Alonso, Carla Lucarelli, Anita Alvarez-Laviada, Claire E. Poulet, Sean O. Bello, Giuseppe Faggian, Cesare M. Terracciano, Julia Gorelik
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Introduction: We investigated the effect of partial mechanical unloading (PMU) of the heart on the physiology of calcium and beta-adrenoceptor-cAMP (βAR-cAMP) microdomains. Previous studies have investigated PMU using a model of heterotopic-heart an
Externí odkaz:
https://doaj.org/article/94beb745a43945ceb14700e29cd60b4a
Autor:
Rengasayee Veeraraghavan, Gregory S Hoeker, Anita Alvarez-Laviada, Daniel Hoagland, Xiaoping Wan, D Ryan King, Jose Sanchez-Alonso, Chunling Chen, Jane Jourdan, Lori L Isom, Isabelle Deschenes, James W Smyth, Julia Gorelik, Steven Poelzing, Robert G Gourdie
Publikováno v:
eLife, Vol 7 (2018)
Computational modeling indicates that cardiac conduction may involve ephaptic coupling – intercellular communication involving electrochemical signaling across narrow extracellular clefts between cardiomyocytes. We hypothesized that β1(SCN1B) –m
Externí odkaz:
https://doaj.org/article/32935da885304be98d92667cd78158c7
Autor:
Oladipupo Adeyemi, Anita Alvarez-Laviada, Francisca Schultz, Effendi Ibrahim, Michael Trauner, Catherine Williamson, Alexey V Glukhov, Julia Gorelik
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0183167 (2017)
BACKGROUND:Increased maternal serum bile acid concentrations in intrahepatic cholestasis of pregnancy (ICP) are associated with fetal cardiac arrhythmias. Ursodeoxycholic acid (UDCA) has been shown to demonstrate anti-arrhythmic properties via preven
Externí odkaz:
https://doaj.org/article/798b971d464547049ab66090493b7cbb
Autor:
Beata Wojciak-Stothard, Vahitha B. Abdul-Salam, Giuseppe Faggian, Michele Miragoli, Roman Y. Medvedev, Julia Gorelik, Anita Alvarez-Laviada, Jose L. Sanchez-Alonso, Eef Dries, Natalia A. Trayanova, Stefano Rossi, Tilo Schorn
Publikováno v:
Hypertension
Pulmonary hypertension is a complex disorder characterized by pulmonary vascular remodeling and right ventricular hypertrophy, leading to right heart failure. The mechanisms underlying this process are not well understood. We hypothesize that the str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69749498ed5a496fdcd1a460bb090727
https://doi.org/10.1161/hypertensionaha.120.14858
https://doi.org/10.1161/hypertensionaha.120.14858
Autor:
H. Surendran, Alice J. Francis, Jahn M. Firth, T. P. Collins, H.‐Y. Ke, Hsiang-Yu Yang, Anita Alvarez-Laviada, Kenneth T. MacLeod
Publikováno v:
The Journal of Physiology
Key points During compensated hypertrophy in vivo fractional shortening (FS) remains constant until heart failure (HF) develops, when FS decreases from 70% to 39%.Compensated hypertrophy is accompanied by an increase in I Na,late and a decrease in Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99c31879d079135842e604cc28412055
https://doi.org/10.1113/jp277038
https://doi.org/10.1113/jp277038