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Daratumumab Plus Atezolizumab in Previously Treated Advanced or Metastatic NSCLC: Brief Report on a Randomized, Open-Label, Phase 1b/2 Study (LUC2001 JNJ-54767414).
Autor: Pillai RN; Department of Hematology and Medical Oncology, Winship Cancer Institute, Atlanta, Georgia., Ramalingam SS; Department of Hematology and Medical Oncology, Winship Cancer Institute, Atlanta, Georgia., Thayu M; Janssen Research & Development, LLC, Titusville, New Jersey., Lorenzini P; Janssen Research & Development, LLC, Spring House, Pennsylvania., Alvarez Arias DA; Janssen Research & Development, LLC, Spring House, Pennsylvania., Moy C; Janssen Research & Development, LLC, Spring House, Pennsylvania., Hutnick N; Janssen Research & Development, LLC, Spring House, Pennsylvania., Knoblauch R; Janssen Research & Development, LLC, Raritan, New Jersey., Feng H; Janssen Research & Development, LLC, Raritan, New Jersey., Kane C; Janssen Research & Development, LLC, Spring House, Pennsylvania., Horn L; Division of Hematology and Oncology, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Reck M; Department of Thoracic Oncology, LungenClinic Grosshansdorf, Airway Research Center North (ARCN), German Center for Lung Research, Grosshansdorf, Germany., Ponce S; Department of Medical Oncology, Hospital Universitario 12 de Octubre, Madrid, Spain.; Centro Nacional de Investigaciones Oncologicas, Madrid, Spain.
Publikováno v: JTO clinical and research reports [JTO Clin Res Rep] 2020 Oct 07; Vol. 2 (2), pp. 100104. Date of Electronic Publication: 2020 Oct 07 (Print Publication: 2021).
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4
Akademický článek
The ap-2 clathrin adaptor mediates endocytosis of an inhibitory killer cell Ig-like receptor in human NK cells.
Autor: Purdy AK; Immune Cell Development and Host Defense Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA 19111;, Alvarez Arias DA; Immune Cell Development and Host Defense Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA 19111;, Oshinsky J; Immune Cell Development and Host Defense Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA 19111;, James AM; Immune Cell Development and Host Defense Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA 19111;, Serebriiskii I; Developmental Therapeutics Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA 19111; and Kazan Federal University, Kazan 420008, Russia., Campbell KS; Immune Cell Development and Host Defense Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA 19111; kerry.campbell@fccc.edu.
Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2014 Nov 01; Vol. 193 (9), pp. 4675-83. Date of Electronic Publication: 2014 Sep 19.
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5
Akademický článek
Disruption of CD8+ Treg activity results in expansion of T follicular helper cells and enhanced antitumor immunity.
Autor: Alvarez Arias DA; Authors' Affiliations: Departments of Department of Gastroenterology, Hepatology, and Infectious Diseases, University of Düsseldorf, Düsseldorf, Germany., Kim HJ, Zhou P, Holderried TA, Wang X, Dranoff G, Cantor H
Publikováno v: Cancer immunology research [Cancer Immunol Res] 2014 Mar; Vol. 2 (3), pp. 207-16. Date of Electronic Publication: 2013 Dec 31.
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6
Akademický článek
In vivo discovery of immunotherapy targets in the tumour microenvironment.
Autor: Zhou P; 1] Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA [2]., Shaffer DR; 1] Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA [2] [3] Jounce Therapeutics, Cambridge, Massachusetts 02138, USA., Alvarez Arias DA; Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA., Nakazaki Y; Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA., Pos W; Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA., Torres AJ; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA., Cremasco V; Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA., Dougan SK; Whitehead Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA., Cowley GS; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA., Elpek K; 1] Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA [2] Jounce Therapeutics, Cambridge, Massachusetts 02138, USA., Brogdon J; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts 02139, USA., Lamb J; Genomics Institute of the Novartis Research Foundation, San Diego, California 92121, USA., Turley SJ; Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA., Ploegh HL; Whitehead Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA., Root DE; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA., Love JC; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA., Dranoff G; Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA., Hacohen N; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA., Cantor H; Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA., Wucherpfennig KW; Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.
Publikováno v: Nature [Nature] 2014 Feb 06; Vol. 506 (7486), pp. 52-7. Date of Electronic Publication: 2014 Jan 29.
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7
Akademický článek
Ubiquitylation of an internalized killer cell Ig-like receptor by Triad3A disrupts sustained NF-κB signaling.
Autor: Miah SM; Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA 19111, USA., Purdy AK, Rodin NB, MacFarlane AW 4th, Oshinsky J, Alvarez-Arias DA, Campbell KS
Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2011 Mar 01; Vol. 186 (5), pp. 2959-69. Date of Electronic Publication: 2011 Jan 26.
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8
Akademický článek
Unexpected role of clathrin adaptor AP-1 in MHC-dependent positive selection of T cells.
Autor: Alvarez Arias DA; Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Boston, MA 02115, USA., McCarty N, Lu L, Maldonado RA, Shinohara ML, Cantor H
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2010 Feb 09; Vol. 107 (6), pp. 2556-61. Date of Electronic Publication: 2010 Jan 25.
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9
Akademický článek
Protein kinase C regulates expression and function of inhibitory killer cell Ig-like receptors in NK cells.
Autor: Alvarez-Arias DA; Division of Basic Science, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA 19111, USA., Campbell KS
Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2007 Oct 15; Vol. 179 (8), pp. 5281-90.
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