Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Aluya Oseghale"'
Autor:
Martin Leustik, Maritza Romero, Helena Pillich, Norman L. Block, Ferenc G. Rick, Jonathan Lawson, Alexander Verin, Aluya Oseghale, Umapathy Siddaramappa, Boris Gorshkov, Evgeny Zemskov, Supriya Sridhar, Istvan Czikora, Rudolf Lucas, Andrew V. Schally, Trinad Chakraborty
Publikováno v:
Toxins, Vol 5, Iss 7, Pp 1244-1260 (2013)
Severe pneumonia is the main single cause of death worldwide in children under five years of age. The main etiological agent of pneumonia is the G+ bacterium Streptococcus pneumoniae, which accounts for up to 45% of all cases. Intriguingly, patients
Externí odkaz:
https://doaj.org/article/f087281299e04b3983ec7d671837bb53
Publikováno v:
Experimental biology and medicine (Maywood, N.J.). 244(2)
Individuals with sickle cell disease have severe anemia due to the production of abnormal hemoglobin S, chronic red blood cell hemolysis, and increased oxidative stress leading to endothelial cell dysfunction, vasculopathy, and progressive organ dama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::969e8d0b2c488f6d350c0c5e26976dc7
https://pubmed.ncbi.nlm.nih.gov/30674214
https://pubmed.ncbi.nlm.nih.gov/30674214
Autor:
Hongyan Xu, Aluya Oseghale, Kenneth R. Peterson, Xingguo Zhu, Ada Rephaeli, Betty S. Pace, Abraham Nudelman, Biaoru Li
Publikováno v:
Blood Cells, Molecules, and Diseases. 79:102345
Pharmacologic induction of fetal hemoglobin (HbF) is an effective strategy for treating sickle cell disease (SCD) by ameliorating disease severity. Hydroxyurea is the only FDA-approved agent that induces HbF, but significant non-responders and requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27c4d70a69a17de04d91173e897d370
https://doi.org/10.1016/j.bcmd.2019.102345
https://doi.org/10.1016/j.bcmd.2019.102345
Autor:
Ferenc G. Rick, Umapathy N. Siddaramappa, Istvan Czikora, Maritza J. Romero, Jonathan Lawson, Andrew V. Schally, Trinad Chakraborty, Evgeny A. Zemskov, Alexander D. Verin, Rudolf Lucas, Norman L. Block, Martin Leustik, Aluya Oseghale, Supriya Sridhar, Boris A. Gorshkov, Helena Pillich
Publikováno v:
Toxins
Toxins, Vol 5, Iss 7, Pp 1244-1260 (2013)
Toxins, Vol 5, Iss 7, Pp 1244-1260 (2013)
Severe pneumonia is the main single cause of death worldwide in children under five years of age. The main etiological agent of pneumonia is the G+ bacterium Streptococcus pneumoniae, which accounts for up to 45% of all cases. Intriguingly, patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9abe0c485806fc680a3b8a020d7a38c7
http://europepmc.org/articles/PMC3737495
http://europepmc.org/articles/PMC3737495
Agonist of growth hormone-releasing hormone reduces pneumolysin-induced pulmonary permeability edema
Autor:
Trinad Chakraborty, Guang Yang, Alexander D. Verin, Norman L. Block, Richard E. White, Aluya Oseghale, Rudolf Lucas, Andrew V. Schally, Michael A. Matthay, Ferenc G. Rick, Supriya Sridhar, Boris A. Gorshkov, Nagavedi S. Umapathy, Evgeny A. Zemskov
Publikováno v:
Proceedings of the National Academy of Sciences. 109:2084-2089
Aggressive treatment with antibiotics in patients infected with Streptococcus pneumoniae induces release of the bacterial virulence factor pneumolysin (PLY). Days after lungs are sterile, this pore-forming toxin can still induce pulmonary permeabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbef5840e3ddc7572185892c9e9af396
https://doi.org/10.1073/pnas.1121075109
https://doi.org/10.1073/pnas.1121075109
Publikováno v:
Blood. 128:1292-1292
Sickle cell disease (SCD) is a pro-inflammatory condition. Levels of TNF-α, IL-6, IL-8, and IL-10 are elevated. There is clear evidence of endothelial cells (EC) dysfunction, and increased leukocyte, and erythrocyte adhesion in patients even in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b124e306ac448e4d9e2066a6982239e
https://doi.org/10.1182/blood.v128.22.1292.1292
https://doi.org/10.1182/blood.v128.22.1292.1292
Publikováno v:
Blood. 128:2480-2480
Introduction: Patients with sickle cell disease (SCD) are suspected to have more pulmonary fibrosis. High resolution computerized tomography can detect interstitial fibrosis although the etiology of this pathology is understudied. A restrictive patte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afcfb550a4eccd280a2dd9fa81187651
https://doi.org/10.1182/blood.v128.22.2480.2480
https://doi.org/10.1182/blood.v128.22.2480.2480
Autor:
Supriya Sridhar, Istvan Czikora, Rudolf Lucas, Sebastian Circo, Robert W. Caldwell, Trinad Chakraborty, Evgeny A. Zemskov, Maritza J. Romero, Stephen D. Cederbaum, Aluya Oseghale, David J. Fulton
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
Frontiers in Immunology
Frontiers in Immunology
The integrity of epithelial and endothelial barriers in the lower airspaces of the lungs has to be tightly regulated, in order to prevent leakage and to assure efficient gas exchange between the alveoli and capillaries. Both G(-) and G(+) bacterial t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59aa816579d9ea2b6a890993786b765
Autor:
Michael A. Matthay, Boris A. Gorshkov, Supruya Sridhar, Norman L. Block, Trinad Chakraborty, Richard E. White, Rudolf Lucas, Ferenc G. Rick, Nagavedi S. Umapathy, Andrew V. Schally, Evgeny A. Zemskov, Aluya Oseghale, Guang Yang
Publikováno v:
B96. MECHANISMS AND MARKERS OF PULMONARY ENDOTHELIAL BARRIER DISRUPTION AND REPAIR.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59b10600f17e1afecf3b93945ab4759c
https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3664
https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3664
Autor:
Martin Leustik, Trinad Chakraborty, Hamid Hossain, Richard E. White, Bernhard Fischer, Mario B. Marrero, Jean-Francois Pittet, Albrecht Wendel, Rudolf Lucas, Aluya Oseghale, Guang Yang
Publikováno v:
The FASEB Journal. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d6791e64212285a91cb68c9308f4307
https://doi.org/10.1096/fasebj.25.1_supplement.1039.22
https://doi.org/10.1096/fasebj.25.1_supplement.1039.22