Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Alus M. Xiaoli"'
Autor:
Xiaofan Yu, Gabrielle Benitez, Peter Tszki Wei, Sofia V. Krylova, Ziyi Song, Li Liu, Meifan Zhang, Alus M. Xiaoli, Henna Wei, Fenfen Chen, Simone Sidoli, Fajun Yang, Kosaku Shinoda, Jeffrey E. Pessin, Daorong Feng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Aging, chronic high-fat diet feeding, or housing at thermoneutrality induces brown adipose tissue (BAT) involution, a process characterized by reduction of BAT mass and function with increased lipid droplet size. Single nuclei RNA sequencing
Externí odkaz:
https://doaj.org/article/7996ce0e511449b6b2d79881227087c6
Autor:
Zhou Fang, Haekyung Lee, Junying Liu, Karen A. Wong, Lewis M. Brown, Xiang Li, Alus M. Xiaoli, Fajun Yang, Ming Zhang
Publikováno v:
Cells, Vol 12, Iss 18, p 2282 (2023)
Myocardial ischemia/reperfusion (I/R) elicits an acute inflammatory response involving complement factors. Recently, we reported that myocardial necrosis was decreased in complement C3−/− mice after heart I/R. The current study used the same hear
Externí odkaz:
https://doaj.org/article/59fb6c00be984157ae75f63323815bc9
Autor:
Ziyi Song, Alus M. Xiaoli, Youlei Li, Gerile Siqin, Tian Wu, Randy Strich, Jeffrey E. Pessin, Fajun Yang
Publikováno v:
Molecular Metabolism, Vol 64, Iss , Pp 101548- (2022)
Objective: Cyclin C (CCNC) is the most conserved subunit of the Mediator complex, which is an important transcription cofactor. Recently, we have found that CCNC facilitates brown adipogenesis in vitro by activating C/EBPα-dependent transcription. H
Externí odkaz:
https://doaj.org/article/d4d1c30ab04043c6b3e5456afaf91239
Autor:
Dou Yeon Youn, Alus M. Xiaoli, Haihong Zong, Junichi Okada, Li Liu, Jacob Pessin, Jeffrey E. Pessin, Fajun Yang
Publikováno v:
Molecular Metabolism, Vol 48, Iss , Pp 101227- (2021)
Objective: Liver glycogen levels are dynamic and highly regulated by nutrient availability as the levels decrease during fasting and are restored during the feeding cycle. However, feeding in the presence of fructose in water suppresses glycogen accu
Externí odkaz:
https://doaj.org/article/623a6c256989414b9c58ce4c2e506581
Publikováno v:
Nutrients, Vol 10, Iss 10, p 1383 (2018)
De novo lipogenesis (DNL) is a complex and highly regulated process in which carbohydrates from circulation are converted into fatty acids that are then used for synthesizing either triglycerides or other lipid molecules. Dysregulation of DNL contrib
Externí odkaz:
https://doaj.org/article/e174976d770046e48586ce1677ab0f62
Autor:
Jacob B. Pessin, Fajun Yang, Yuling Chi, Li Liu, Alus M. Xiaoli, Jeffrey E. Pessin, Irwin J. Kurland, Yunping Qiu, Dou Yeon Youn
Publikováno v:
Physiol Genomics
Excessive long-term consumption of dietary carbohydrates, including glucose, sucrose, or fructose, has been shown to have significant impact on genome-wide gene expression, which likely results from changes in metabolic substrate flux. However, there
Autor:
Jeffrey E. Pessin, Yuling Chi, Jacob B. Pessin, Fajun Yang, Dou Yeon Youn, Alus M. Xiaoli, Li Liu
Publikováno v:
J Biol Chem
The liver maintains metabolic homeostasis by integrating the regulation of nutrient status with both hormonal and neural signals. Many studies on hepatic signaling in response to nutrients have been conducted in mice. However, no in-depth study is cu
Autor:
Alus M. Xiaoli, Li Liu, Fajun Yang, Jacob B. Pessin, Jeffrey E. Pessin, Dou Yeon Youn, Haihong Zong, Junichi Okada
Publikováno v:
Molecular Metabolism, Vol 48, Iss, Pp 101227-(2021)
Molecular Metabolism
Molecular Metabolism
Objective Liver glycogen levels are dynamic and highly regulated by nutrient availability as the levels decrease during fasting and are restored during the feeding cycle. However, feeding in the presence of fructose in water suppresses glycogen accum
Publikováno v:
J Biol Chem
The sterol regulatory element-binding proteins (SREBPs) are a family of transcription factors best known for stimulating the expression of genes encoding key lipogenic enzymes. However, SREBP functions beyond lipid metabolism are less understood. Her
Autor:
Jacob B. Pessin, Alus M. Xiaoli, Dou Yeon Youn, Li Liu, Jeffrey E. Pessin, Fajun Yang, Yuling Chi
C57BL/6J and BALB/cJ mouse strains were analyzed by deep mRNA sequencing of the liver in the fasted state and following ingestion of standard laboratory mouse chow supplemented with plain drinking water or water containing 20% glucose, sucrose or fru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::555b8d4ce8975e6f2167f7fa29959571
https://doi.org/10.1101/2020.11.11.378497
https://doi.org/10.1101/2020.11.11.378497