Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Alummoottil V. Joshua"'
Publikováno v:
Synthetic Communications. 38:434-440
A new short and highly efficient synthesis of (5)‐2,3‐dimethoxy‐N[(1‐ethyl‐2‐pyrrolidinyl)methyl]‐5‐iodobenzamide (epidepride, 1) from 3‐methoxy‐salicylaldehyde (o‐vanillin, 2) and 3‐methoxysalicyclic acid (6) was achieved by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3006427bdeb20e05619a42e9ca7a72c9
https://doi.org/10.1080/00397910701771199
https://doi.org/10.1080/00397910701771199
Autor:
Weizhong Zheng, Alexander J.B. McEwan, Sanjay K. Sharma, Alummoottil V. Joshua, Douglas N. Abrams
Publikováno v:
ChemInform. 40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c4eefff83ae4519e5929e5b8e9d71b7
https://doi.org/10.1002/chin.200909194
https://doi.org/10.1002/chin.200909194
Publikováno v:
ChemInform. 39
A new short and highly efficient synthesis of (5)‐2,3‐dimethoxy‐N[(1‐ethyl‐2‐pyrrolidinyl)methyl]‐5‐iodobenzamide (epidepride, 1) from 3‐methoxy‐salicylaldehyde (o‐vanillin, 2) and 3‐methoxysalicyclic acid (6) was achieved by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc2ab65564f31d9d4c877608690d19da
https://doi.org/10.1002/chin.200827116
https://doi.org/10.1002/chin.200827116
Autor:
Sanjay K. Sharma, Alexander J.B. McEwan, Alummoottil V. Joshua, Douglas N. Abrams, Weizhong Zheng
Publikováno v:
Bioorganicmedicinal chemistry letters. 18(20)
Synthesis of 4-amino-4,6-androstadiene-3,17-dione 7, an analog of formestane used in breast cancer therapy as an aromatase inhibitor, from 4-acetoxy-4-androstene-3,17-dione 2 is described. This is the first report of a 4-amino diene (4,6) system in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d46d84dabc1566c04adb19f0de5699
https://pubmed.ncbi.nlm.nih.gov/18815032
https://pubmed.ncbi.nlm.nih.gov/18815032
Autor:
Mathew T. Martin-Iverson, Sanjay K. Sharma, Alummoottil V. Joshua, John R. Scott, Alexander J.B. McEwan, Douglas N. Abrams, Alicia Strelkov, Peter H. Silverstone
Publikováno v:
ChemInform. 38
8-Iodo-11-(4-methylpiperazino)-5H-dibenzo[b,e][1,4]-diazepine: Iozapine, a potential D4-receptor ligand was synthesized using oxidative iodo-destannylation reaction. The preliminary biodistribution studies of radioiodinated iozapine have shown that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff1acbbad84488d805fdbe25ef18ff1
https://doi.org/10.1002/chin.200744161
https://doi.org/10.1002/chin.200744161
Autor:
John R. Scott, Carrie A. Morin, Michael Smylie, Alummoottil V. Joshua, Alexander J.B. McEwan, J. Wayne Logus, Thomas G. Salopek
Publikováno v:
European journal of nuclear medicine. 28(4)
The role of nuclear medicine in the management of patients with malignant melanoma has expanded in recent years with the introduction of lymphoscintigraphy and sentinel lymph node biopsy, intense interest in positron emission tomography (PET) imaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580710a0e91cd0e13acda640650aa6b4
https://pubmed.ncbi.nlm.nih.gov/11357490
https://pubmed.ncbi.nlm.nih.gov/11357490
Publikováno v:
Biochemistry. 21:419-428
The quinone antitumor antibiotics saframycins A and C bind to duplex DNA and G,C containing complementary oligodeoxyribonucleotides at pHs below 5.5 via selective protonation of the antibiotics at the N-12 positions in an equilibrium process. This bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d8be65f394141f9579b765eb6ce70d3
https://doi.org/10.1021/bi00532a001
https://doi.org/10.1021/bi00532a001
Autor:
J. William Lown, Alummoottil V. Joshua
Publikováno v:
Canadian Journal of Chemistry. 55:508-521
Bromonium nitrate (generated in situ by the reaction of bromine with silver nitrate in chloroform–pyridine) reacts trans-stereospecifically and regiospecifically in eiectrophilic additions to a series of Z–E pairs of alkenes to give bromoalkyl ni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::508a9e94959d189a6c459a08d34e99f9
https://doi.org/10.1139/v77-071
https://doi.org/10.1139/v77-071
Autor:
J. William Lown, Alummoottil V. Joshua
Publikováno v:
Biochemical Pharmacology. 28:2017-2026
The synthesis of 3,3-dimethyl-4-oxo-3,4-dihydroquinoline (16), 3,3-dimethyl-4-oxo-2-methoxy-1,2,3,4-tetrahydroquinoline (17). and of 1 1a-S-pyrrolo(1, 4)benzodiazepine (21) as models to study the mechanism of action of the pyrrolo(1, 4)benzodiazepine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29f56bc185532b06a5fc91df4a47c914
https://doi.org/10.1016/0006-2952(79)90218-1
https://doi.org/10.1016/0006-2952(79)90218-1
Autor:
Alummoottil V. Joshua, J. William Lown
Publikováno v:
Canadian Journal of Chemistry. 55:122-130
Iodonium nitrate (generated by reaction of iodine chloride with silver nitrate in chloroform–pyridine) reacts with a variety of unsaturated substrates to form the following: 1,4-conjugate addition products of the type alkenyl pyridinium nitrates; a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67428f3579e13e202e6a66f333450be3
https://doi.org/10.1139/v77-022
https://doi.org/10.1139/v77-022