Examining sterically demanding lysine analogs for histone lysine methyltransferase catalysis.

Autor: Temimi AHKA; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands., Tran V; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands., Teeuwen RS; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands., Altunc AJ; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands., Amatdjais-Groenen HIV; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands., White PB; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands., Lenstra DC; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands., Proietti G; Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, 5230, Odense, Denmark., Wang Y; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands.; Department of Blood Transfusion, China-Japan Union Hospital, Jilin University, 126 Xiantai Street, Changchun, 130033, P.R. China., Wegert A; Mercachem B.V., Kerkenbos 1013, 6546 BB, Nijmegen, The Netherlands., Blaauw RH; Chiralix B.V., Kerkenbos 1013, 6546 BB, Nijmegen, The Netherlands., Qian P; Chemistry and Material Science Faculty, Shandong Agricultural University, 271018, Tai'an, Shandong, P.R. China., Ren W; Chemistry and Material Science Faculty, Shandong Agricultural University, 271018, Tai'an, Shandong, P.R. China., Guo H; Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TN, 37996, USA. hguo1@utk.edu., Mecinović J; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands. mecinovic@sdu.dk.; Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, 5230, Odense, Denmark. mecinovic@sdu.dk.

Publikováno v: Scientific reports [Sci Rep] 2020 Feb 28; Vol. 10 (1), pp. 3671. Date of Electronic Publication: 2020 Feb 28.