Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Altug Koc"'
Autor:
Caner Karaca, Ezgi Demir Karaman, Asim Leblebici, Hasan Kurter, Hulya Ellidokuz, Altug Koc, Ender Berat Ellidokuz, Zerrin Isik, Yasemin Basbinar
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Metastatic colorectal cancer (CRC) is still in need of effective treatments. This study applies a holistic approach to propose new targets for treatment of primary and liver metastatic CRC and investigates their therapeutic potential in-vitr
Externí odkaz:
https://doaj.org/article/e617b716505c4d7e8ab10b11c98fc827
Autor:
Zerrin Isik, Asım Leblebici, Ezgi Demir Karaman, Caner Karaca, Hulya Ellidokuz, Altug Koc, Ender Berat Ellidokuz, Yasemin Basbinar
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0267973 (2022)
Adenomatous polyps of the colon are the most common neoplastic polyps. Although most of adenomatous polyps do not show malign transformation, majority of colorectal carcinomas originate from neoplastic polyps. Therefore, understanding of this transfo
Externí odkaz:
https://doaj.org/article/0cc662cdfd824d5cb28f28d5690d8b1e
Autor:
Altug Koc, Ozge Ozer Kaya, Berk Ozyilmaz, Yasar B. Kutbay, Ozgur Kirbiyik, Taha R. Ozdemir, Kadri M. Erdogan, Merve Saka Guvenc, Deniz C. Oztekin, Mehmet Ozeren, Halil G. Pala, Atalay Ekin, Cenk Gezer, Alkim G. Sahingoz Yildirim, Bahar Konuralp Atakul, Secil Kurtulmus, Ugur Turhan, Cuneyt E. Taner
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 7, Iss 7, Pp n/a-n/a (2019)
Abstract Background Next‐generation sequencing (NGS) and discovery of fetal cell‐free DNA (cfDNA) in the maternal circulation render possible prenatal screening for trisomy 21 (Down syndrome), trisomy 18, trisomy 13, and sex chromosome aneuploidi
Externí odkaz:
https://doaj.org/article/64aa45006b664fc4a1c3f66f8b9cc2f2
Autor:
Elcin Bora, Ahmet Okay Caglayan, Altug Koc, Tufan Cankaya, Hande Ozkalayci, Mehmet Kocabey, Demet Kemer, Suleyman Aksoy, Zumre Arican Alicikus, Isil Basara Akin, Merih Guray Durak, Duygu Gurel, Tugba Yavuzsen, Ali Sevinc, Isil Somali, Ilknur Gorken, Pinar Balci, Aziz Karaoglu, Serdar Saydam, Ayfer Ulgenalp
Publikováno v:
Cancer Genetics. :118-133
Breast cancer, a worldwide leading cause of cancer in women, may occur in familial cases. Germline mutations in BRCA1/2 genes are responsible for 15% of the familial cases. With the power of next generation sequencing (NGS) analysis, it is possible t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe0be5a3332e50787514b42a27d0564
https://doi.org/10.1016/j.cancergen.2022.02.006
https://doi.org/10.1016/j.cancergen.2022.02.006
Autor:
Pınar Günay Aslan, Ahmet Oktay Çağlayan, Elçin Bora, Altuğ Koç, Hilal Yücel, Ayfer Ülgenalp, Yeşil Öztürk, Gül Şeker, Mesut Akarsu
Publikováno v:
The Turkish Journal of Gastroenterology, Vol 35, Iss 5, Pp 374-384 (2024)
Background/Aims: Peutz–Jeghers syndrome (PJS) is a rare hereditary disorder linked to increased cancer risk due to specific genetic variants in the STK11 gene. This study aimed to assess disease manifestations, genetic profiles, and genotype–phen
Externí odkaz:
https://doaj.org/article/1ffdba67604b4e03b2a1534108671dca
Autor:
Berk Ozyilmaz, Yasar B. Kutbay, Kadri Murat Erdoğan, Taha Reşid Özdemir, Merve Saka Guvenc, Altug Koc, Ozgur Kirbiyik, Ozge Ozer Kaya
Publikováno v:
J Pediatr Genet
Prader–Willi, Angelman, Beckwith–Wiedemann, and Russell–Silver are imprinting syndromes. In this study, we aimed to compare the efficiency of single nucleotide polymorphism (SNP) microarray analysis with methylation-specific Multiplex ligation-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84cdd4a47f5c87a86a2e62363682a7d0
https://doi.org/10.1055/s-0039-1698420
https://doi.org/10.1055/s-0039-1698420
Autor:
Merve Saka Guvenc, Gül Caner Mercan, Kadri Murat Erdoğan, Samira Özkara, Altug Koc, Ozge Ozer Kaya, Berk Ozyilmaz, Ozgur Kirbiyik, Taha Reşid Özdemir, Yasar B. Kutbay
Publikováno v:
Turkish Archives of Otorhinolaryngology, Vol 57, Iss 3, Pp 140-148 (2019)
Objective The aim of this study is to investigate the efficiency of a first-line molecular genetic evaluation approach, in children with deafness. Methods Patients who were found to have sensorineural hearing loss by age-appropriate audiological test
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dcd48e1e1ed6a666c2e1690fcb000a4
https://doi.org/10.5152/tao.2019.4320
https://doi.org/10.5152/tao.2019.4320
Autor:
Taha Reşid Özdemir, Can Ozturk, Altug Koc, Yasar B. Kutbay, Kadri Murat Erdoğan, Ozge Kaya Ozer, Ozgur Kirbiyik, Berk Ozyilmaz, Merve Saka Guvenc
Publikováno v:
International journal of immunogenetics. 46(4)
Periodic fever syndromes (PFSs) are a family of clinical disorders, which are characterized by recurrent episodes of fever in the absence of microbial, autoimmune or malign conditions. Most common types of PFSs are associated with four genes: MEFV, M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e019f1c115b04f9d1bc43af8c6ea9c0
https://pubmed.ncbi.nlm.nih.gov/31135083
https://pubmed.ncbi.nlm.nih.gov/31135083
Publikováno v:
Neurology India. 69:181
The chromosome 22q11.2 region is highly susceptible to both microdeletions and microduplications that have been known to be responsible for multiple congenital anomaly disorders. We describe a patient of 22q11.2 duplication syndrome presenting with b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890c8696711e0502977c549f492d080e
https://doi.org/10.4103/0028-3886.310061
https://doi.org/10.4103/0028-3886.310061
Autor:
Tuncay Goksel, Su Özgür, Aslı Tetik Vardarlı, Altuğ Koç, Haydar Soydaner Karakuş, Taha Reşid Özdemir, Kadri Murat Erdoğan, Ceyda Aldağ, Ali Veral, Berna Komurcuoglu, Pınar Gursoy, Mehmet Emin Arayici, Asim Leblebici, Türkan Yiğitbaşı, Hülya Ellidokuz, Yasemin Basbinar
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
IntroductionLung cancer (LC) is a leading cause of cancer-related mortality worldwide. Approximately 80% of LC cases are of the non-small cell lung cancer (NSCLC) type, and approximately two-thirds of these cases are diagnosed in advanced stages. Onl
Externí odkaz:
https://doaj.org/article/57288c4ea24c40eeb23772fa84cf3f73