Zobrazeno 1 - 10
of 1 346
pro vyhledávání: '"Alton B"'
Autor:
Alton B. Farris, Mariam P. Alexander, Ulysses G. J. Balis, Laura Barisoni, Peter Boor, Roman D. Bülow, Lynn D. Cornell, Anthony J. Demetris, Evan Farkash, Meyke Hermsen, Julien Hogan, Renate Kain, Jesper Kers, Jun Kong, Richard M. Levenson, Alexandre Loupy, Maarten Naesens, Pinaki Sarder, John E. Tomaszewski, Jeroen van der Laak, Dominique van Midden, Yukako Yagi, Kim Solez
Publikováno v:
Transplant International, Vol 36 (2023)
The Banff Digital Pathology Working Group (DPWG) was established with the goal to establish a digital pathology repository; develop, validate, and share models for image analysis; and foster collaborations using regular videoconferencing. During the
Externí odkaz:
https://doaj.org/article/3787b1837f31459b8eb3bb03b6acf0fb
Autor:
Robin Schmitz, Miriam Manook, Zachary Fitch, Imran Anwar, Isabel DeLaura, Danae Olaso, Ashley Choi, Janghoon Yoon, Yeeun Bae, Mingqing Song, Alton B. Farris, Jean Kwun, Stuart Knechtle
Publikováno v:
Frontiers in Transplantation, Vol 2 (2023)
IntroductionOne-third of HLA-incompatible kidney transplant recipients experience antibody mediated rejection (AMR) with limited treatment options. This study describes a novel treatment strategy for AMR consisting of proteasome inhibition and costim
Externí odkaz:
https://doaj.org/article/d6ea67d48a0748f3a4d2932d898a1dee
Autor:
Jacqueline G. O’Leary, MD, MPH, Alton B. Farris, MD, Howard M. Gebel, PhD, Sumeet K. Asrani, MD, Medhat Askar, PhD, Vanessa Garcia, BS, George J. Snipes, MD, Denise J. Lo, MD, Stuart J. Knechtle, MD, Goran B. Klintmalm, MD, PhD, Anthony J. Demetris, MD
Publikováno v:
Transplantation Direct, Vol 9, Iss 8, p e1500 (2023)
Background. Liver allografts protect renal allografts from the same donor from some, but not all, preformed donor specific alloantibodies (DSA). However, the precise mechanisms of protection and the potential for more subtle alterations/injuries with
Externí odkaz:
https://doaj.org/article/c5d023d96c18455eb233152ff43e79d3
Autor:
Michael Brandon Ware, Maggie Phillips, Christopher McQuinn, Mohammad Y. Zaidi, Hannah M. Knochelmann, Emily Greene, Brian Robinson, Cameron J. Herting, Thomas A. Mace, Zhengjia Chen, Chao Zhang, Matthew R. Farren, Amanda N. Ruggieri, Jacob S. Bowers, Reena Shakya, Alton B. Farris, Gregory Young, William E. Carson III, Bassel El-Rayes, Chrystal M. Paulos, Gregory B. Lesinski
Publikováno v:
JCI Insight, Vol 8, Iss 8 (2023)
This study aimed to enhance antitumor immune responses to pancreatic cancer via Ab-based blockade of IL-6 and cytotoxic T-lymphocyte–associated protein 4 (CTLA-4). Mice bearing s.c. or orthotopic pancreatic tumors were treated with blocking Abs to
Externí odkaz:
https://doaj.org/article/c9e661e36d174f30b84405ca8e2d56e4
Publikováno v:
Hepatology Communications, Vol 6, Iss 5, Pp 980-994 (2022)
Activation of extracellular signal–regulated kinase (ERK) 1/2 promotes hepatocyte proliferation in response to growth stimuli, but whether constitutive hepatocyte ERK1/2 signaling functions in liver physiology is unknown. To examine the role of ERK
Externí odkaz:
https://doaj.org/article/3879aec32238490c9a64f17f79a44bd9
Autor:
M. Alvaro Berbís, David S. McClintock, Andrey Bychkov, Jeroen Van der Laak, Liron Pantanowitz, Jochen K. Lennerz, Jerome Y. Cheng, Brett Delahunt, Lars Egevad, Catarina Eloy, Alton B. Farris, III, Filippo Fraggetta, Raimundo García del Moral, Douglas J. Hartman, Markus D. Herrmann, Eva Hollemans, Kenneth A. Iczkowski, Aly Karsan, Mark Kriegsmann, Mohamed E. Salama, John H. Sinard, J. Mark Tuthill, Bethany Williams, César Casado-Sánchez, Víctor Sánchez-Turrión, Antonio Luna, José Aneiros-Fernández, Jeanne Shen
Publikováno v:
EBioMedicine, Vol 88, Iss , Pp 104427- (2023)
Summary: Background: Artificial intelligence (AI) is rapidly fuelling a fundamental transformation in the practice of pathology. However, clinical integration remains challenging, with no AI algorithms to date in routine adoption within typical anato
Externí odkaz:
https://doaj.org/article/4b6861aefe91458ca64e641a24309825
Autor:
Dominic Sinibaldi, Gabor G Illei, Wendy I White, S Sam Lim, Jason Cobb, Ahmad Akhgar, Lingmin Zeng, Alton B Farris, Monica Battle, David Chain, Jennifer A Cann
Publikováno v:
Lupus Science and Medicine, Vol 10, Iss 1 (2023)
Objective Lupus nephritis (LN) is diagnosed by biopsy, but longitudinal monitoring assessment methods are needed. Here, in this preliminary and hypothesis-generating study, we evaluate the potential for using urine proteomics as a non-invasive method
Externí odkaz:
https://doaj.org/article/96a750e6e45844798878b7804593e4aa
Autor:
Catherine C. Cohen, Eduardo Castillo‐Leon, Alton B. Farris, Shelley A. Caltharp, Rebecca L. Cleeton, Elizabeth M. Sinclair, Diane E. Shevell, Morten A. Karsdal, Mette Juul Fisker Nielsen, Diana J. Leeming, Miriam B. Vos
Publikováno v:
Hepatology Communications, Vol 5, Iss 11, Pp 1860-1872 (2021)
Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease in children and may lead to cirrhosis requiring liver transplant. Thus, prompt diagnosis of advanced fibrosis is essential. Our objectives were to examine PRO‐C3 (a neo‐ep
Externí odkaz:
https://doaj.org/article/7a7dda75194c44619e8a03c2243eac4f
Autor:
Robin Schmitz, Zachary W. Fitch, Paul M. Schroder, Ashley Y. Choi, Miriam Manook, Janghoon Yoon, Mingqing Song, John S. Yi, Sanjay Khandelwal, Gowthami M. Arepally, Alton B. Farris, Edimara S. Reis, John D. Lambris, Jean Kwun, Stuart J. Knechtle
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Donor-specific antibodies in sensitized recipients may cause kidney transplant rejection. Here the authors show that complement component C3 inhibition prolongs graft survival by inhibiting T and B cell proliferation/activation and hence tissue injur
Externí odkaz:
https://doaj.org/article/9003312b88304e17b0bd7ab46a8e6ace
Publikováno v:
Kidney International Reports, Vol 6, Iss 6, Pp 1738-1742 (2021)
Externí odkaz:
https://doaj.org/article/c1911c142ba447bbb02a2a7e5f9d2d86