Dual role of a GTPase conformational switch for membrane fusion by mitofusin ubiquitylation

Autor: Schuster, Ramona, Anton, Vincent, Simões, Tânia, Altin, Selver, den Brave, Fabian, Hermanns, Thomas, Hospenthal, Manuela, Komander, David, Dittmar, Gunnar, Dohmen, R. Jürgen

Publikováno v: Life Science Alliance, 3 (1)

Mitochondria are essential organelles whose function is upheld by their dynamic nature. This plasticity is mediated by large dynamin-related GTPases, called mitofusins in the case of fusion between two mitochondrial outer membranes. Fusion requires u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71027c1b6e4eb23315a638fc02bb6510

Role of ubiquitin in the regulation of yeast and mammalian mitofusins

Autor: Altin, Selver

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______199::b46df7835d264fb28b1e2f64795e5782
https://kups.ub.uni-koeln.de/8557/

Dual role of a GTPase conformational switch for membrane fusion by mitofusin ubiquitylation.

Autor: Schuster R; Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany., Anton V; Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany., Simões T; Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany., Altin S; Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany., den Brave F; Department of Molecular Cell Biology, Max Planck Institute of Biochemistry, Martinsried, Germany., Hermanns T; Institute for Genetics, University of Cologne, Cologne, Germany., Hospenthal M; Institute of Molecular Biology and Biophysics, Eidgenössische Technische Hochschule Zürich, Zürich, Switzerland., Komander D; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.; Ubiquitin Signalling Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, Australia., Dittmar G; Proteomics of Cellular Signalling, Luxembourg Institute of Health, Strassen, Luxembourg., Dohmen RJ; Institute for Genetics, University of Cologne, Cologne, Germany., Escobar-Henriques M; Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany Mafalda.Escobar@uni-koeln.de.

Publikováno v: Life science alliance [Life Sci Alliance] 2019 Dec 19; Vol. 3 (1). Date of Electronic Publication: 2019 Dec 19 (Print Publication: 2020).