Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Altholactone"'
Autor:
Ali R. Elnaas, Darren Grice, Jianying Han, Yunjiang Feng, Angela Di Capua, Tin Mak, Joseph A. Laureanti, Garry W. Buchko, Peter J. Myler, Gregory Cook, Ronald J. Quinn, Miaomiao Liu
Publikováno v:
Molecules, Vol 25, Iss 10, p 2384 (2020)
Elucidation of the mechanism of action of compounds with cellular bioactivity is important for progressing compounds into future drug development. In recent years, phenotype-based drug discovery has become the dominant approach to drug discovery over
Externí odkaz:
https://doaj.org/article/f67b691dc6334238809aabf8ec0b7f0f
Akademický článek
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Publikováno v:
Molecules, Vol 16, Iss 6, Pp 4560-4566 (2011)
The antimicrobial activity of altholactone, a naturally extracted styryllactone isolated from Goniothalamus malayanus, was determined against Gram positive (S. aureus ATTC 25923, S. aureus ATTC 25392, and E. faecalis ATTC 29212) and Gram negative (E.
Externí odkaz:
https://doaj.org/article/60086067a8db48a79ae000c9852271a6
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Chunwa Jiang, Muqaddas Masood, Azhar Rasul, Wei Wei, Ya Wang, Muhammad Ali, Muhammad Mustaqeem, Jiang Li, Xiaomeng Li
Publikováno v:
Molecules, Vol 22, Iss 2, p 240 (2017)
Altholactone, a natural compound isolated from Goniothalamus spp., has demonstrated anti-inflammatory and anticancer activities, but its molecular mechanisms are still not fully defined. Nuclear factor kappa B (NF-κB) and signal transducer and activ
Externí odkaz:
https://doaj.org/article/94dbda18e0274d9e828329c6a0241c79
Publikováno v:
Tetrahedron Letters. 59:4024-4027
Syntheses of (+)-altholactone isolated from Goniothalamus giganteus and its C-7 epimer (+)-7-epi-altholactone, (−)-etharvensin and (+)-alumheptolide-A were achieved. The lactone ring of these compounds was constructed using Pd-catalyzed carbonylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e7e8f1d95052ede0d93c1d55ace9f2a
https://doi.org/10.1016/j.tetlet.2018.09.062
https://doi.org/10.1016/j.tetlet.2018.09.062
Akademický článek
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Autor:
Jirayut Euanorasetr, Bamroong Munyoo, Onanong Vorasin, Watanalai Panbangred, Mayura Junhom, Patoomratana Tuchinda, Srisurang Tantimavanich
Publikováno v:
Journal of Asian Natural Products Research. 18:462-474
Altholactone exhibited the anti-fungal activity with a high MIC value of 128 μg ml−1 against Cryptococcus neoformans and Saccharomyces cerevisiae. Fifteen ester derivatives of altholactone 1–15 were modified by esterification and their structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9489c064ce29d6eb594c1c19407945ba
https://doi.org/10.1080/10286020.2015.1133611
https://doi.org/10.1080/10286020.2015.1133611
Autor:
Puey Ounjai, Arthit Chairoungdua, Panupong Mahalapbutr, Thanyada Rungrotmongkol, Bamroong Munyoo, Sarunya Kitdumrongthum, Kanoknetr Suksen, Patoomratana Tuchinda, Somrudee Reabroi
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 127, Iss, Pp 110149-(2020)
Topoisomerase IIα enzyme (Topo IIα) plays a critical function in DNA replication process and is considered to be a promising target of anti-cancer drugs. In the present study, we reported that the altholactone derivatives modified by adding a halog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61d9bccc5f43fa61621e5565ae74363
https://doi.org/10.1016/j.biopha.2020.110149
https://doi.org/10.1016/j.biopha.2020.110149
Autor:
Gregory M. Cook, Jianying Han, Miaomiao Liu, Garry W. Buchko, Ronald J. Quinn, Yunjiang Feng, Joseph A. Laureanti, Tin Mak, Ali R. Elnaas, Darren Grice, Peter J. Myler, Angela Di Capua
Publikováno v:
Molecules
Volume 25
Issue 10
Molecules, Vol 25, Iss 2384, p 2384 (2020)
Volume 25
Issue 10
Molecules, Vol 25, Iss 2384, p 2384 (2020)
Elucidation of the mechanism of action of compounds with cellular bioactivity is important for progressing compounds into future drug development. In recent years, phenotype-based drug discovery has become the dominant approach to drug discovery over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e4ba3caafcf264c00d275db82df6141
https://doi.org/10.3390/molecules25102384
https://doi.org/10.3390/molecules25102384