Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Althea N. Waldhart"'
Autor:
Tracey Avequin, Kin H. Lau, Althea N. Waldhart, Hannah Guak, Holly Dykstra, Connie Krawczyk, Ning Wu
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107163- (2023)
Summary: Obese individuals experience low grade inflammation initiated within their adipose tissue. However, the early events that lead to the release of these inflammatory factors from adipose tissue are poorly characterized. To separate glucose eff
Externí odkaz:
https://doaj.org/article/0368fc9a315e495197f489861e05bdad
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106538- (2023)
Summary: While TXNIP (thioredoxin interacting protein) in the plasma membrane and vesicular location is known to negatively regulate cellular glucose uptake by facilitating glucose transporter endocytosis, the function of TXNIP in the nucleus is far
Externí odkaz:
https://doaj.org/article/83167db2dc5b46b2bdf2956d7379a0be
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105848- (2023)
Summary: Brown adipose tissue (BAT) has the ability to burn calories as heat. Utilizing BAT thermogenesis is thus an attractive way to combat obesity. However, the transcriptional network resulting in the lipid synthesis to oxidation shift during the
Externí odkaz:
https://doaj.org/article/ef8065ddfd0840fcaadee79c73ede1fe
Autor:
Althea N. Waldhart, Holly Dykstra, Anderson S. Peck, Elissa A. Boguslawski, Zachary B. Madaj, Jennifer Wen, Kelsey Veldkamp, Matthew Hollowell, Bin Zheng, Lewis C. Cantley, Timothy E. McGraw, Ning Wu
Publikováno v:
Cell Reports, Vol 19, Iss 10, Pp 2005-2013 (2017)
Growth factors, such as insulin, can induce both acute and long-term glucose uptake into cells. Apart from the rapid, insulin-induced fusion of glucose transporter (GLUT)4 storage vesicles with the cell surface that occurs in muscle and adipose tissu
Externí odkaz:
https://doaj.org/article/a58356eb6c39434f87cd0a17eaba62cb
Autor:
Cassi LaRose, Ning Wu, Holly Dykstra, Gongpu Zhao, Chelsea Fisk, Xing Meng, Althea N. Waldhart
Publikováno v:
Biochim Biophys Acta Biomembr
GLUT1 is a major glucose facilitator expressed ubiquitously among tissues. Upregulation of its expression plays an important role in the development of many types of cancer and metabolic diseases. Thioredoxin-interacting protein (TXNIP) is an α-arre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b582900de1e27177a9dcc6e3d7d067af
https://europepmc.org/articles/PMC8464517/
https://europepmc.org/articles/PMC8464517/
Autor:
Cassi LaRose, Xing Meng, Althea N. Waldhart, Gongpu Zhao, Chelsea Fisk, Ning Wu, Holly Dykstra
Publikováno v:
Archives of biochemistry and biophysics. 700
Fatty acids are essential cellular building blocks and a major energy source. Regardless of their metabolic fate, fatty acids first need to be activated by forming a thioester with a coenzyme A group. This reaction is carried out by acyl-CoA syntheta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c4a8fe8ab132eb2130dec991a419f06
https://pubmed.ncbi.nlm.nih.gov/33485846
https://pubmed.ncbi.nlm.nih.gov/33485846
Autor:
Brejnev M. Muhire, Xianlin Han, J. Andrew Pospisilik, Ning Wu, Holly Dykstra, Ben A. Johnson, Zachary Madaj, Emily Wolfrum, Althea N. Waldhart, Dean J. Pettinga, Vanessa Wegert
Publikováno v:
Cell reports
SUMMARY Hyperglycemia affects over 400 million individuals worldwide. The detrimental health effects are well studied at the tissue level, but the in vivo effects at the organelle level are poorly understood. To establish such an in vivo model, we us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae98048ad9100b0fcc057df5d888744
https://doi.org/10.1016/j.celrep.2021.109488
https://doi.org/10.1016/j.celrep.2021.109488
Autor:
Kelsey L. Veldkamp, Lewis C. Cantley, Timothy E. McGraw, Althea N. Waldhart, Ning Wu, Anderson Peck, Jennifer Wen, Holly Dykstra, Matthew T. Hollowell, Zachary Madaj, Bin Zheng, Elissa Boguslawski
Publikováno v:
Cell Reports, Vol 19, Iss 10, Pp 2005-2013 (2017)
Summary Growth factors, such as insulin, can induce both acute and long-term glucose uptake into cells. Apart from the rapid, insulin-induced fusion of glucose transporter (GLUT)4 storage vesicles with the cell surface that occurs in muscle and adipo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bedad0b5c4db987e0712ec34dece987
https://doi.org/10.1016/j.celrep.2017.05.041
https://doi.org/10.1016/j.celrep.2017.05.041