Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Althea A. Capul"'
Publikováno v:
Journal of Virology. 85:3172-3178
Arenaviruses are negative-strand RNA viruses that cause human diseases such as lymphocytic choriomeningitis, Bolivian hemorrhagic fever, and Lassa hemorrhagic fever. No licensed vaccines exist, and current treatment is limited to ribavirin. The proto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd893911e5ec78d9e202ccc16a032872
https://doi.org/10.1128/jvi.02081-10
https://doi.org/10.1128/jvi.02081-10
Structural characterization of the Z RING-eIF4E complex reveals a distinct mode of control for eIF4E
Autor:
Laurent Volpon, Michael J. Osborne, Katherine L. B. Borden, Juan Carlos de la Torre, Althea A. Capul
Publikováno v:
Proceedings of the National Academy of Sciences. 107:5441-5446
The eukaryotic translation initiation factor eIF4E, a potent oncogene, is highly regulated. One class of eIF4E regulators, including eIF4G and the 4E-binding proteins (4E-BPs), interact with eIF4E using a conserved YXXXXLΦ-binding site. The structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea212867cb589722583ade227f0cea5
https://doi.org/10.1073/pnas.0909877107
https://doi.org/10.1073/pnas.0909877107
Autor:
Nágila Francinete Costa Secundino, Althea A. Capul, Phillip G. Lawyer, Stephen M. Beverley, David B. Sacks, Nicola Kimblin, Salvatore J. Turco, Nathan C. Peters
Publikováno v:
Cellular Microbiology. 12:906-918
Leishmania synthesize abundant phosphoglycan-containing molecules made up of [Gal-Man-PO(4)] repeating units, including the surface lipophosphoglycan (LPG), and the surface and secreted proteophosphoglycan (PPG). The vector competence of Phlebotomus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64eaadb62e6b98ca3c46f68a66239a89
https://doi.org/10.1111/j.1462-5822.2010.01439.x
https://doi.org/10.1111/j.1462-5822.2010.01439.x
Autor:
Suzanne M. Hickerson, Althea A. Capul, Stephen M. Beverley, Tamara Barron, Salvatore J. Turco
Publikováno v:
Infection and Immunity. 75:4629-4637
Abundant surface Leishmania phosphoglycans (PGs) containing [Gal(β1,4)Man(α1-PO 4 )]-derived repeating units are important at several points in the infectious cycle of this protozoan parasite. PG synthesis requires transport of activated nucleotide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dcf89ceb6677129ddb8b61c0bcd00c9
https://doi.org/10.1128/iai.00735-07
https://doi.org/10.1128/iai.00735-07
Autor:
Althea A. Capul, Mar Perez, Emily Burke, Michael J. Buchmeier, Juan Carlos de la Torre, Stefan Kunz
Publikováno v:
Journal of Virology. 81:9451-9460
Generation of infectious arenavirus-like particles requires the virus RING finger Z protein and surface glycoprotein precursor (GPC) and the correct processing of GPC into GP1, GP2, and a stable signal peptide (SSP). Z is the driving force of arenavi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089fe79ade9d31ebbb285738d8bd89d3
https://doi.org/10.1128/jvi.00499-07
https://doi.org/10.1128/jvi.00499-07
Autor:
Kristeene A. Knopp, Cyrille J. Bonhomme, Althea A. Capul, Elvin J. Lauron, Michael J. Buchmeier, Lydia H. Bederka
Publikováno v:
Virology. 409(2)
The glycoprotein of lymphocytic choriomeningitis virus (LCMV) contains nine potential N-linked glycosylation sites. We investigated the function of these N-glycosylations by using alanine-scanning mutagenesis. All the available sites were occupied on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64007e026faf94b37ead17f0a428e16e
https://pubmed.ncbi.nlm.nih.gov/21056893
https://pubmed.ncbi.nlm.nih.gov/21056893
Autor:
Stephen M. Beverley, Dong Liu, Chahnaz Kebaier, Nazzy Pakpour, Phillip Scott, Althea A. Capul, Jude E. Uzonna
Publikováno v:
Infection and immunity. 77(8)
The precise role of Leishmania glycoconjugate molecules including phosphoglycans (PGs) and lipophosphoglycan (LPG) on host cellular responses is still poorly defined. Here, we investigated the interaction of Leishmania major LPG2 null mutant ( lpg2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb5b921873ec0bcc6ed06cc6aadb4e08
https://pubmed.ncbi.nlm.nih.gov/19487470
https://pubmed.ncbi.nlm.nih.gov/19487470
Publikováno v:
Virology. 382(1)
Several arenaviruses cause hemorrhagic fever (HF) disease in humans for which there are no licensed vaccines, and current therapy is limited to the use of ribavirin (Rib) that is only partially effective and associated with significant side effects.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07aabc10fbaec7d98b2b67e185e62e3a
https://pubmed.ncbi.nlm.nih.gov/18929379
https://pubmed.ncbi.nlm.nih.gov/18929379
In the protozoan parasite Leishmania, abundant surface and secreted molecules such as lipophosphoglycan (LPG)1 and proteophosphoglycans (PPGs) contain extensive galactose residues in the form of phosphoglycans (PGs) containing [Gal-Man-PO4] repeating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fafed6a7324f7456ee1555677c73951d
https://europepmc.org/articles/PMC2807729/
https://europepmc.org/articles/PMC2807729/
Publikováno v:
Journal of virology. 79(7)
We examined herpes simplex virus (HSV)-infected human HEp-2 cells or porcine cells that express herpes virus entry mediator (HVEM) for virus and receptor protein interactions. Antibody to HVEM, or its viral ligand gD, coimmunoprecipitated several sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2803ab550cf5d67874d138233524447
https://pubmed.ncbi.nlm.nih.gov/15767456
https://pubmed.ncbi.nlm.nih.gov/15767456