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of 384
pro vyhledávání: '"Alternative cleavage and polyadenylation (APA)"'
Akademický článek
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Autor:
Dharmalingam P; Department of Biochemistry, Saveetha Dental College & Hospitals, Saveetha Institute of Medical & Technical Sciences, Saveetha University, Chennai, India., Mahalingam R; Laboratory of Neuroimmunology, Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Yalamanchili HK; Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.; Department of Pediatrics - Neurology, Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, Texas, USA.; Department of Pediatrics, USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas, USA., Weng T; Department of Biochemistry and Molecular Biology & Divisions of Critical Care, Pulmonary and Sleep Medicine, Department of Internal Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA., Karmouty-Quintana H; Department of Biochemistry and Molecular Biology & Divisions of Critical Care, Pulmonary and Sleep Medicine, Department of Internal Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA., Guha A; Department of Cardiology, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA., A Thandavarayan R; Department of Cardiology, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Publikováno v:
Journal of cellular physiology [J Cell Physiol] 2022 Jan; Vol. 237 (1), pp. 149-160. Date of Electronic Publication: 2021 Aug 11.
Autor:
Ashrith Guha, Harry Karmouty-Quintana, Hari Krishna Yalamanchili, Prakash Dharmalingam, Rajarajan Amirthalingam Thandavarayan, Rajasekaran Mahalingam, Tingting Weng
Publikováno v:
Journal of Cellular Physiology. 237:149-160
In the messenger RNA (mRNA) maturation process, the 3'-end of pre-mRNA is cleaved and a poly(A) sequence is added, this is an important determinant of mRNA stability and its cellular functions. More than 60%-70% of human genes have three or more poly
Autor:
Li, Zhuangyue
We hypothesize that DNA methylation regulates alternative cleavage and polyadenylation (APA) by modulating chromatin loops, and that abnormal DNA methylation could shift normal chromatin structure to achieve cancer-specific APA isoform expression. Se
Autor:
Cacioppo, Roberta1 (AUTHOR) rcacioppo@mrc-lmb.cam.ac.uk, Rad, Deniz1 (AUTHOR), Pagani, Giulia2 (AUTHOR), Gandellini, Paolo2 (AUTHOR), Lindon, Catherine1 (AUTHOR) acl34@cam.ac.uk
Publikováno v:
PLoS ONE. 11/11/2024, Vol. 19 Issue 11, p1-20. 20p.
Autor:
Chen, Qingchuan1 (AUTHOR), Liu, Zhouyang2 (AUTHOR), Tan, Yuen1 (AUTHOR), Pan, Siwei1 (AUTHOR), An, Wen1 (AUTHOR), Xu, Huimian1 (AUTHOR) xuhuimian@126.com
Publikováno v:
Cancer Medicine. Jan2023, Vol. 12 Issue 1, p879-897. 19p.
Autor:
Mehravar, Majid1 (AUTHOR), Ghaemimanesh, Fatemeh2 (AUTHOR), Poursani, Ensieh M.3 (AUTHOR) e-poursani@razi.tums.ac.ir
Publikováno v:
Cancer Biomarkers. 2022, Vol. 34 Issue 4, p563-570. 8p.
Publikováno v:
Frontiers in Immunology; 2024, p1-11, 11p
Publikováno v:
Pflugers Archiv
The human transcriptome is highly dynamic, with each cell type, tissue, and organ system expressing an ensemble of transcript isoforms that give rise to considerable diversity. Apart from alternative splicing affecting the “body” of the transcrip
Autor:
Qiang Zhang, Bin Tian
Publikováno v:
Biochemical Society Transactions; Jun2023, Vol. 51 Issue 3, p1111-1119, 9p