Altered balance between self-reactive T helper (Th)17 cells and Th10 cells and between full-length forkhead box protein 3 (FoxP3) and FoxP3 splice variants in Hashimoto's thyroiditis

Autor: H. O. Madsen, B. Kristensen, Terry J. Smith, Laszlo Hegedüs, Claus Henrik Nielsen

Publikováno v: Kristensen, B, Hegedüs, L, Smith, T J & Nielsen, C H 2015, ' Altered balance between self-reactive T helper (Th)17 cells and Th10 cells and between full-length forkhead box protein 3 (FoxP3) and FoxP3 splice variants in Hashimoto's thyroiditis ', Clinical and Experimental Allergy, vol. 180, no. 1, pp. 58-69 . https://doi.org/10.1111/cei.12557

Summary T helper type 17 (Th17) cells play a pathogenic role in autoimmune disease, while interleukin (IL)-10-producing Th10 cells serve a protective role. The balance between the two subsets is regulated by the local cytokine milieu and by the relat

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https://pubmed.ncbi.nlm.nih.gov/25412700