Zobrazeno 1 - 10
of 266
pro vyhledávání: '"Altanserin"'
Akademický článek
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Autor:
Susanne Nikolaus, Hans-Jörg Wittsack, Christina Antke, Markus Beu, Hubertus Hautzel, Cvetana Decheva, Eduards Mamlins, Yuriko Mori, Joseph P. Huston, Gerald Antoch, Hans-Wilhelm Müller
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Purpose: The 5-HT2A receptor (R) is known to modulate dopamine (DA) release in the mammalian brain. Altanserin (ALT) and 2,5-dimethoxy-4-iodoamphetamine (DOI) act as 5-HT2AR antagonist and agonist, respectively. In the present study, we assessed the
Externí odkaz:
https://doaj.org/article/924d4bbe6b6649778627c980bb761157
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Makoto Higuchi, Jun Maeda, Yoko Ikoma, Hiroyuki Takuwa, Kazunori Kawamura, Tetsuya Suhara, Asuka Nishino, Ming-Rong Zhang, Takayuki Obata
Publikováno v:
Annals of Nuclear Medicine. 35:955-965
Positron emission tomography (PET) has been used to investigate changes in the concentration of endogenous neurotransmitters. Recently, this technique has been applied to the imaging of serotonin2A receptors using [18F]altanserin. In these measuremen
Autor:
Rebeca Diez-Alarcia, Aintzane García-Bea, Carolina Muguruza, Abraham Martín, Jordi Llop, Vanessa Gómez-Vallejo, Guadalupe Rivero, Luis F. Callado, J. Javier Meana
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Addi. Archivo Digital para la Docencia y la Investigación
instname
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Translational Psychiatry
Addi. Archivo Digital para la Docencia y la Investigación
instname
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Translational Psychiatry
The status of serotonin 5HT2A receptors (5HT2ARs) in schizophrenia has been controversial. In vivo positron emission tomography neuroimaging and in vitro post-mortem binding studies have reported conflicting results about 5HT2AR density. Radiotracers
Autor:
Brice Ozenne, Gitte M. Knudsen, Patrick M. Fisher, Marie Spies, Peter S. Jensen, Arafat Nasser
Publikováno v:
Human Brain Mapping
Spies, M, Nasser, A, Ozenne, B, Jensen, P S, Knudsen, G M & Fisher, P M 2020, ' Common HTR2A variants and 5-HTTLPR are not associated with human in vivo serotonin 2A receptor levels ', Human Brain Mapping, vol. 41, no. 16, pp. 4518-4528 . https://doi.org/10.1002/hbm.25138
Spies, M, Nasser, A, Ozenne, B, Jensen, P S, Knudsen, G M & Fisher, P M 2020, ' Common HTR2A variants and 5-HTTLPR are not associated with human in vivo serotonin 2A receptor levels ', Human Brain Mapping, vol. 41, no. 16, pp. 4518-4528 . https://doi.org/10.1002/hbm.25138
The serotonin 2A receptor (5‐HT2AR) is implicated in the pathophysiology and treatment of various psychiatric disorders. [18F]altanserin and [11C]Cimbi‐36 positron emission tomography (PET) allow for high‐resolution imaging of 5‐HT2AR in the
Autor:
Eduards Mamlins, Hubertus Hautzel, Cvetana Decheva, Gerald Antoch, Joseph P. Huston, Hans-Jörg Wittsack, Hans-Wilhelm Müller, Markus Beu, Yuriko Mori, Susanne Nikolaus, Christina Antke
Publikováno v:
Frontiers in Neuroscience
Frontiers in Neuroscience, Vol 15 (2021)
Frontiers in Neuroscience, Vol 15 (2021)
Purpose: The 5-HT2A receptor (R) is known to modulate dopamine (DA) release in the mammalian brain. Altanserin (ALT) and 2,5-dimethoxy-4-iodoamphetamine (DOI) act as 5-HT2AR antagonist and agonist, respectively. In the present study, we assessed the
Autor:
Yasuyuki Kimura, Tetsuya Suhara, Ming-Rong Zhang, Hiroki Hashimoto, Satoshi Kuwabara, Hiroshi Ito, Takehito Ito, Shigeki Hirano, Chie Seki, Kazuho Kojima, Makiko Yamada, Makoto Higuchi, Keita Yokokawa, Keisuke Takahata, Kazunori Kawamura, Yoko Ikoma
Publikováno v:
bioRχiv.
Rationale The tendency to avoid punishment, called behavioral inhibition system, is an essential aspect of motivational behavior. Behavioral inhibition system is related to negative affect, such as anxiety, depression and pain, but its neural basis h
Autor:
Gitte M. Knudsen, Siv Thorlund Peitersen, Mengfei Xiong, Matthias M. Herth, Lene Lundgaard Donovan, Nikolaj Speth, Andreas Kjaer, Arafat Nasser, Fraser G. Edgar, Ida Vang Andersen, Hanne D. Hansen, Mikael Palner, Vladimir Shalgunov, Simone L. Baerentzen, Nakul Ravi Raval, Stina Syvänen, Elina T. L’Estrade
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-11 (2020)
EJNMMI Research
Shalgunov, V, Xiong, M, L’Estrade, E T, Raval, N R, Andersen, I V, Edgar, F G, Speth, N R, Baerentzen, S L, Hansen, H D, Donovan, L L, Nasser, A, Peitersen, S T, Kjaer, A, Knudsen, G M, Syvänen, S, Palner, M & Herth, M M 2020, ' Blocking of efflux transporters in rats improves translational validation of brain radioligands ', EJNMMI Research, vol. 10, no. 1, 124 . https://doi.org/10.1186/s13550-020-00718-x
EJNMMI Research
Shalgunov, V, Xiong, M, L’Estrade, E T, Raval, N R, Andersen, I V, Edgar, F G, Speth, N R, Baerentzen, S L, Hansen, H D, Donovan, L L, Nasser, A, Peitersen, S T, Kjaer, A, Knudsen, G M, Syvänen, S, Palner, M & Herth, M M 2020, ' Blocking of efflux transporters in rats improves translational validation of brain radioligands ', EJNMMI Research, vol. 10, no. 1, 124 . https://doi.org/10.1186/s13550-020-00718-x
Background Positron emission tomography (PET) is a molecular imaging technique that can be used to investigate the in vivo pharmacology of drugs. Initial preclinical evaluation of PET tracers is often conducted in rodents due to the accessibility of
Autor:
J. John Mann, Chester A. Mathis, Jamie Zelazny, Wayne C. Drevets, Zhiqun Gong, Harry Rubin-Falcone, Allison V. Metts, David A. Brent, R. Todd Ogden
Publikováno v:
Archives of Suicide Research. 23:122-133
Objective: To determine serotonin system abnormalities related to major depression or previous suicidal behavior.Methods: [11C]WAY100635, [18F]altanserin and positron emission tomography were used ...