Výsledky vyhledávání - "Altaf S. Kazi"

Admission plasma levels of the neuronal injury marker neuron-specific enolase are associated with mortality and delirium in sepsis

Autor: Dennis L. Kolson, Jessica A. Palakshappa, Alex Wysoczanski, John P. Reilly, Mark E. Mikkelsen, William D. Schweickert, Anna Tommasini, Nuala J. Meyer, Altaf S. Kazi, Thomas G. Dunn, Jason D. Christie, Michael G.S. Shashaty, Brian J. Anderson

Publikováno v: Journal of Critical Care. 36:18-23

Purpose Neuron-specific enolase (NSE) concentrations are prognostic following traumatic and anoxic brain injury and may provide a method to quantify neuronal injury in other populations. We determined the association of admission plasma NSE concentra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5265b1b935374ecc564522581400034
https://doi.org/10.1016/j.jcrc.2016.06.012

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Genetic Variation in the Prostaglandin E2 Pathway Is Associated with Primary Graft Dysfunction

Publikováno v: American Journal of Respiratory and Critical Care Medicine. 189:567-575

Rationale: Biologic pathways with significant genetic conservation across human populations have been implicated in the pathogenesis of primary graft dysfunction (PGD). The evaluation of the role of recipient genetic variation in PGD has thus far bee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad4587556da5bbc23f7ced2e1491b53
https://doi.org/10.1164/rccm.201307-1283oc

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Neutropenic sepsis is associated with distinct clinical and biological characteristics: a cohort study of severe sepsis

Autor: Michael G.S. Shashaty, Brian J. Anderson, Jason D. Christie, Dudley Charles, Mark E. Mikkelsen, John P. Reilly, Anna Tommasini, Thomas G. Dunn, Nuala J. Meyer, Kristin M. Hudock, Altaf S. Kazi

Publikováno v: Critical Care

Background Immunocompromised patients who develop sepsis while neutropenic are at high risk for morbidity and mortality; however, it is unknown if neutropenic sepsis is associated with distinct clinical and biological characteristics. Methods We cond

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd871e6b6a351fa7e992a3ec9dfda77f
https://doi.org/10.1186/s13054-016-1398-y

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Low Plasma Levels of Adiponectin Do Not Explain Acute Respiratory Distress Syndrome Risk: a Prospective Cohort Study of Patients with Severe Sepsis

Autor: Altaf S. Kazi, Caroline A. G. Ittner, Thomas G. Dunn, Nuala J. Meyer, Ryo Ueno, Jessica A. Palakshappa, Qufei Wu, John P. Reilly, Dudley Charles, Michael G.S. Shashaty, Brian J. Anderson, Jason D. Christie, Anna Tommasini

Publikováno v: Critical Care

Background Obesity is associated with the development of acute respiratory distress syndrome (ARDS) in at-risk patients. Low plasma levels of adiponectin, a circulating hormone-like molecule, have been implicated as a possible mechanism for this asso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588e9277c443c35ff65dfe0c9d1ed227
https://doi.org/10.1186/s13054-016-1244-2

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Binding of peroxiredoxin 6 to substrate determines differential phospholipid hydroperoxide peroxidase and phospholipase A2 activities

Autor: Chandra Dodia, Aron B. Fisher, Altaf S. Kazi, Sheldon I. Feinstein, Tea Shuvaeva, Yefim Manevich

Publikováno v: Archives of Biochemistry and Biophysics. 485:139-149

Peroxiredoxin 6 (Prdx6) differs from other mammalian peroxiredoxins both in its ability to reduce phospholipid hydroperoxides at neutral pH and in having phospholipase A(2) (PLA(2)) activity that is maximal at acidic pH. We previously showed an activ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::649479cb9c4bebd4eb1801342505ca60
https://doi.org/10.1016/j.abb.2009.02.008

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Oxidant stress stimulates expression of the human peroxiredoxin 6 gene by a transcriptional mechanism involving an antioxidant response element

Autor: Ibrul Chowdhury, Altaf S. Kazi, Yiqun Mo, Ling Gao, Aron B. Fisher, Sheldon I. Feinstein

Publikováno v: Free Radical Biology and Medicine. 46:146-153

Peroxiredoxin 6 (Prdx6) is a unique antioxidant enzyme that can reduce phospholipid and other hydroperoxides. A549 cells, a human lung-derived cell line, express both Prdx6 and Nrf2, a transcription factor that binds to antioxidant-response elements

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::48b1d8b91ec7dcb822c81dc8c9190289
https://doi.org/10.1016/j.freeradbiomed.2008.09.027

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Role of P63 (CKAP4) in binding of surfactant protein-A to type II pneumocytes

Autor: Aron B. Fisher, Daniel S. Gonder, Jian-Qin Tao, Sheldon I. Feinstein, Sandra R. Bates, Altaf S. Kazi, Kevin Yu

Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 295:L658-L669

We have recently described a putative receptor for lung surfactant protein-A (SP-A) on rat type II pneumocytes. The receptor, P63, is a 63-kDa type II transmembrane protein. Coincubation of type II cells with P63 antibody (Ab) reversed the inhibitory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bb451c9a50cfd5233f3aa4280319899
https://doi.org/10.1152/ajplung.90233.2008

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Role of the PI3-kinase signaling pathway in trafficking of the surfactant protein A receptor P63 (CKAP4) on type II pneumocytes

Autor: Li Zhang, Jian-Qin Tao, Aron B. Fisher, Altaf S. Kazi, Sheldon I. Feinstein, Sandra R. Bates

Surfactant protein A (SP-A) plays an important role in the maintenance of lung lipid homeostasis. Previously, an SP-A receptor, P63 (CKAP4), on type II pneumocyte plasma membranes (PM) was identified by chemical cross-linking techniques. An antibody

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c2824e349a2071acb3f2d651a62c941
https://europepmc.org/articles/PMC3006267/

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