Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Altaf A. Kondkar"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/b3fd9fe8782f4b1bb9aea201f5bf318e
Autor:
Altaf A. Kondkar, Tahira Sultan, Taif A. Azad, Tanvir Khatlani, Abdulaziz A. Alshehri, Essam A. Osman, Glenn P. Lobo, Faisal A. Almobarak, Saleh A. Al-Obeidan
Publikováno v:
Biology, Vol 13, Iss 1, p 62 (2024)
Adult-onset glaucoma, an age-related neurodegenerative disease, is very prevalent among the elderly Arabs of Saudi origin. This study investigated the association between apolipoprotein E (APOE) gene variants (rs429358 and rs7412) and primary open-an
Externí odkaz:
https://doaj.org/article/73e7913bcd2e45bf8e1220c6953c7163
Autor:
Altaf A. Kondkar, Taif A. Azad, Tahira Sultan, Essam A. Osman, Faisal A. Almobarak, Glenn P. Lobo, Saleh A. Al-Obeidan
Publikováno v:
PLoS ONE, Vol 18, Iss 4 (2023)
Aim In a retrospective and exploratory case-control study, we examined the genetic association of two common polymorphisms in the 3’ untranslated region (UTR) of DICER1 (rs3742330) and DROSHA (rs10719) genes in primary open-angle glaucoma (POAG) an
Externí odkaz:
https://doaj.org/article/f1c7fa910cbc42f38c071f8aafb1a75c
Autor:
Altaf A. Kondkar, Tahira Sultan, Taif A. Azad, Essam A. Osman, Faisal A. Almobarak, Glenn P. Lobo, Saleh A. Al-Obeidan
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Objective: It is plausible that common disease mechanisms exist in glaucoma pathophysiology. Accordingly, we investigated the genetic association of two previously reported primary open-angle glaucoma (POAG)-related gene polymorphisms, rs2472493 (A >
Externí odkaz:
https://doaj.org/article/fffa71bc0ef44173943b20844a5917d7
Autor:
Altaf A. Kondkar, Tahira Sultan, Taif A. Azad, Essam A. Osman, Faisal A. Almobarak, Saleh A. Al-Obeidan
Publikováno v:
BMC Medical Genetics, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background Glaucoma is a polygenic neurodegenerative disease and the second most common cause of blindness in Saudi Arabia. To test the hypothesis that genetic variants in the genes involved in the bone morphogenic protein (BMP) signaling pa
Externí odkaz:
https://doaj.org/article/cd6faad0b9334fa5a1835ac04cfdf7e0
Autor:
Altaf A. Kondkar, Taif A. Azad, Abdullah S. Alobaidan, Tahira Sultan, Essam A. Osman, Faisal A. Almobarak, Glenn P. Lobo, Saleh A. Al-Obeidan
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Objective: Recent studies have demonstrated an association of single nucleotide polymorphisms (SNPs) rs35934224 in TXNRD2 and rs6478746 near LMX1B genes in primary open-angle glaucoma (POAG) among Europeans. We performed a retrospective, case-control
Externí odkaz:
https://doaj.org/article/764365d3dfad4c9386bec4409559fa58
Autor:
Altaf A. Kondkar, Taif A. Azad, Tahira Sultan, Faisal A. Al-Mobarak, Hatem Kalantan, Saleh A. Al-Obeidan
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-6 (2019)
Abstract Objective The genetic spectrum of primary open-angle glaucoma (POAG) in middle-eastern Saudi’s is still elusive. To this end, we investigated an association between rs693421, rs2499601 and their haplotypes at chromosome 1q43 locus with POA
Externí odkaz:
https://doaj.org/article/eda68b26a2db470ea08e5e9163c0885c
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/1c8cc649cfff4be3b91ae82e08771ea3
Autor:
Altaf A. Kondkar, Taif A. Azad, Tahira Sultan, Essam A. Osman, Faisal A. Almobarak, Saleh A. Al-Obeidan
Publikováno v:
Journal of Ophthalmology, Vol 2020 (2020)
Purpose. To determine the association between plasma 8-hydroxy-2′-deoxyguanosine (8-OHdG) levels, a marker for oxidative DNA damage, and patients with primary open-angle glaucoma (POAG) or its clinical phenotypes. Furthermore, we also examined the
Externí odkaz:
https://doaj.org/article/f5370fad22f647198037661817b44395
Autor:
Altaf A. Kondkar, Tahira Sultan, Faisal A. Almobarak, Hatem Kalantan, Khaled K. Abu-Amero, Saleh A. Al-Obeidan
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-5 (2018)
Abstract Objective Plexin domain containing 2 (PLXDC2), a cell surface transmembrane protein receptor for pigment epithelium derived factor, is expressed in many tissues including the eye. Polymorphism rs7081455 flanking PLXDC2 has been associated wi
Externí odkaz:
https://doaj.org/article/2f2b8ed72624411e89063c53d65fcf55