Výsledky vyhledávání - "Altıntop Mehlika Dilek"

Akademický článek

In vitro evaluation of 2-pyrazoline derivatives as DPP-4 inhibitors

Autor: Temel Halide Edip, Altıntop Mehlika Dilek, Sever Belgin, Özdemir Ahmet, Akalın Çiftçi Gülşen

Publikováno v: Türk Biyokimya Dergisi, Vol 48, Iss 1, Pp 104-109 (2022)

In this study, the synthesis of three pyrazoline derivatives and the evaluation of their inhibitory effects on dipeptidyl peptidase (DPP-4) were aimed.

Externí odkaz: https://doaj.org/article/5797907e44084af6b3acebabecc72b3d

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Akademický článek

A new series of 2,4-thiazolidinediones endowed with potent aldose reductase inhibitory activity

Autor: Sever Belgin, Altıntop Mehlika Dilek, Demir Yeliz, Türkeş Cüneyt, Özbaş Kaan, Çiftçi Gülşen Akalın, Beydemir Şükrü, Özdemir Ahmet

Publikováno v: Open Chemistry, Vol 19, Iss 1, Pp 347-357 (2021)

5-(2-Hydroxy-3-methylbenzylidene)thiazolidine-2,4-dione (3) was identified as the most potent AR inhibitor in this series, exerting uncompetitive inhibition with a K i value of 0.445 ± 0.013 µM.

Externí odkaz: https://doaj.org/article/03a0d48773c847ef8df4ffe894c420df

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Akademický článek

Biological evaluation of a series of benzothiazole derivatives as mosquitocidal agents

Autor: Sever Belgin, Altıntop Mehlika Dilek, Özdemir Ahmet, Tabanca Nurhayat, Estep Alden S., Becnel James J., Bloomquist Jeffrey R.

Publikováno v: Open Chemistry, Vol 17, Iss 1, Pp 288-294 (2019)

Aedes aegypti is associated with the transmission of numerous human and animal diseases, such as yellow fever, dengue fever, chikungunya, and more recently Zika virus. Emerging insecticide resistance has created a need to develop new mosquitocidal ag

Externí odkaz: https://doaj.org/article/ba587ca705d6497fbe217b0b1b066fc2

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