Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alshaimaa Adawy"'
Autor:
Anna Willms, Hella Schupp, Michelle Poelker, Alshaimaa Adawy, Jan Frederik Debus, Torsten Hartwig, Tim Krichel, Jürgen Fritsch, Steven Singh, Henning Walczak, Silvia von Karstedt, Heiner Schäfer, Anna Trauzold
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-12 (2021)
Abstract TNF-related apoptosis-inducing ligand (TRAIL) receptor 2 (TRAIL-R2) can induce apoptosis in cancer cells upon crosslinking by TRAIL. However, TRAIL-R2 is highly expressed by many cancers suggesting pro-tumor functions. Indeed, TRAIL/TRAIL-R2
Externí odkaz:
https://doaj.org/article/01faaca6a4584d9ebb8d543b9bdea437
Autor:
Johanna Ebmeyer, Stefanie Hessel-Pras, Albert Braeuning, Colin J. Henderson, Georgia Guenther, Alshaimaa Adawy, Anne-Margarethe Enge, Alfonso Lampen, Raymond Reif, Jan G. Hengstler
Publikováno v:
Archives of Toxicology. 94:219-229
Pyrrolizidine alkaloids (PAs) are widely occurring phytotoxins which can induce severe liver damage in humans and other mammalian species by mechanisms that are not fully understood. Therefore, we investigated the development of PA hepatotoxicity in
Autor:
Saša Frank, Kathrin Gianmoena, Carsten Watzl, Alshaimaa Adawy, Jan G. Hengstler, Katharina Grgas, Joanna Stewart, Cheng Cheng Zhang, Rosemarie Marchan, Fredrik Pontén, Birte Hellwig, Heiko Hayen, Alexander Schriewer, Cristina Cadenas, Dennis Franckenstein, Jörg Rahnenführer, Maren Claus, Michaela S. Lesjak, Patrick Micke, Sonja Vosbeck, Annika Glotzbach, Sonja Thaler, Karolina Edlund, Katrin Madjar, Adil Mardinoglu, Marcus Schmidt, Heiko U. Käfferlein
Publikováno v:
International journal of cancer, 145(4):901-915
Cadenas, C, Vosbeck, S, Edlund, K, Grgas, K, Madjar, K, Hellwig, B, Adawy, A, Glotzbach, A, Stewart, J D, Lesjak, M S, Franckenstein, D, Claus, M, Hayen, H, Schriewer, A, Gianmoena, K, Thaler, S, Schmidt, M, Micke, P, Pontén, F, Mardinoglu, A, Zhang, C, Käfferlein, H U, Watzl, C, Frank, S, Rahnenführer, J, Marchan, R & Hengstler, J G 2019, ' LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer ', International Journal of Cancer, vol. 145, no. 4, pp. 901-915 . https://doi.org/10.1002/ijc.32138
International Journal of Cancer
Cadenas, C, Vosbeck, S, Edlund, K, Grgas, K, Madjar, K, Hellwig, B, Adawy, A, Glotzbach, A, Stewart, J D, Lesjak, M S, Franckenstein, D, Claus, M, Hayen, H, Schriewer, A, Gianmoena, K, Thaler, S, Schmidt, M, Micke, P, Pontén, F, Mardinoglu, A, Zhang, C, Käfferlein, H U, Watzl, C, Frank, S, Rahnenführer, J, Marchan, R & Hengstler, J G 2019, ' LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer ', International Journal of Cancer, vol. 145, no. 4, pp. 901-915 . https://doi.org/10.1002/ijc.32138
International Journal of Cancer
Endothelial lipase (LIPG) is a cell surface associated lipase that displays phospholipase A1 activity towards phosphatidylcholine present in high‐density lipoproteins (HDL). LIPG was recently reported to be expressed in breast cancer and to support
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dbe3d59641ddfcbd0139fa73f899671
https://eprints.soton.ac.uk/436970/
https://eprints.soton.ac.uk/436970/
Autor:
Ufuk Mert, Verena Haselmann, Anna Trauzold, Anna Willms, Johannes Lemke, Juergen Fritsch, Cynthia Colmorgen, Pierre Teichmann, Silvia von Karstedt, Elisabeth Scharff, Alshaimaa Adawy
Publikováno v:
Cancers
Volume 11
Issue 8
Cancers, Vol 11, Iss 8, p 1167 (2019)
Volume 11
Issue 8
Cancers, Vol 11, Iss 8, p 1167 (2019)
Binding of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to the plasma membrane TRAIL-R1/-R2 selectively kills tumor cells. This discovery led to evaluation of TRAIL-R1/-R2 as targets for anti-cancer therapy, yet the corresponding c
Autor:
Nadine Rommerswinkel, Jan G. Hengstler, Bernd Niggemann, Alshaimaa Adawy, Thomas Dittmar, Silvia Keil, Kurt S. Zänker
Publikováno v:
Cellular signalling. 52
The interplay of ErbB receptor homo- and heterodimers plays a crucial role in the pathology of breast cancer since activated signal transduction cascades coordinate proliferation, survival and migration of cells. EGF and β-Heregulin are well charact
Autor:
Marcus Schmidt, Georgia Günther, Wiebke Schormann, Nachiket Vartak, Jutta Schröder, Alshaimaa Adawy, Ahmed Ghallab, Jan G. Hengstler, Raymond Reif
Members of the receptor tyrosine kinase family (RTK) have been shown to be present in the nucleus of cells; however, the mechanisms underlying their trafficking to the nucleus, and their relevance once there are poorly understood. In the present stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9ae45171bf497f043b04c4d0814f6ec
https://europepmc.org/articles/PMC4759164/
https://europepmc.org/articles/PMC4759164/