Therapeutic Potential of a Novel Vitamin D 3 Oxime Analogue, VD1-6, with CYP24A1 Enzyme Inhibitory Activity and Negligible Vitamin D Receptor Binding.

Autor: Alshabrawy, Ali K.^1,2 (AUTHOR) ali.alshabrawy@mymail.unisa.edu.au, Cui, Yingjie^3,4 (AUTHOR) yingjiecui@sina.cn, Sylvester, Cyan¹ (AUTHOR) cyan.sylvester@mymail.unisa.edu.au, Yang, Dongqing⁵ (AUTHOR) dongqing.yang@adelaide.edu.au, Petito, Emilio S.¹ (AUTHOR) emilio.petito@mymail.unisa.edu.au, Barratt, Kate R.¹ (AUTHOR) kate.barratt@unisa.edu.au, Sawyer, Rebecca K.¹ (AUTHOR) rebecca.sawyer@unisa.edu.au, Heatlie, Jessica K.¹ (AUTHOR) jessica_kate.heatlie@mymail.unisa.edu.au, Polara, Ruhi¹ (AUTHOR) polra001@mymail.unisa.edu.au, Sykes, Matthew J.¹ (AUTHOR) matt.sykes@unisa.edu.au, Atkins, Gerald J.⁵ (AUTHOR) gerald.atkins@adelaide.edu.au, Hickey, Shane M.¹ (AUTHOR) shane.hickey@unisa.edu.au, Wiese, Michael D.¹ (AUTHOR) michael.wiese@unisa.edu.au, Stringer, Andrea M.¹ (AUTHOR) andrea.stringer@unisa.edu.au, Liu, Zhaopeng³ (AUTHOR) liuzhaop@sdu.edu.cn, Anderson, Paul H.¹ (AUTHOR) paul.anderson@unisa.edu.au

Publikováno v: Biomolecules (2218-273X). Jul2022, Vol. 12 Issue 7, pN.PAG-N.PAG. 14p.

LC-MS/MS analysis of vitamin D3 metabolites in human serum using a salting-out based liquid-liquid extraction and DAPTAD derivatization

Autor: Doug A. Brooks, Amanda Bergamin, Shane M. Hickey, Deepti K Sharma, Michael D. Wiese, Peter D. O’Loughlin, Paul H. Anderson, Ali K. Alshabrawy

Publikováno v: Journal of Chromatography B. 1173:122654

LC-MS/MS has recently emerged as the best-practice for simultaneous analysis of vitamin D metabolites. We have developed and validated an LC-MS/MS method for simultaneous quantification of 25(OH)D3, 24,25(OH)2D3, and 3-epi-25(OH)D3 in human serum. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a206ff5c5843ca4b883b150b7409b7d
https://doi.org/10.1016/j.jchromb.2021.122654