Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Alpna Seth"'
Autor:
Alpna Seth, Douglas S. Bowman, David L. Raden, Fredric S. Fay, Fernando A. Gonzalez, Roger J. Davis
Publikováno v:
The Journal of Cell Biology
The mitogen-activated protein (MAP) kinase signal transduction pathway represents an important mechanism by which growth factors regulate cell function. Targets of the MAP kinase pathway are located within several cellular compartments. Signal transd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ce4a9bf323d09747680e57f7fb7316
https://doi.org/10.1083/jcb.122.5.1089
https://doi.org/10.1083/jcb.122.5.1089
Publikováno v:
Molecular and Cellular Biology. 13:4125-4136
The product of the c-myc gene (c-Myc) is a sequence-specific DNA-binding protein that has previously been demonstrated to be required for cell cycle progression. Here we report that the c-Myc DNA binding site confers cell cycle regulation to a report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937c65386dd37c3169fe0eabdccff9b4
https://doi.org/10.1128/mcb.13.7.4125
https://doi.org/10.1128/mcb.13.7.4125
Publikováno v:
Proceedings of the National Academy of Sciences. 90:3216-3220
The product of the human c-myc protooncogene (Myc) is a sequence-specific DNA binding protein. Here, we demonstrate that the placement of the specific Myc DNA binding site CACGTG upstream of a luciferase reporter gene conferred Myc-stimulated express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9f62f232c251bd35d9484c3fc23ec4
https://doi.org/10.1073/pnas.90.8.3216
https://doi.org/10.1073/pnas.90.8.3216
Publikováno v:
Journal of Biological Chemistry. 267:24796-24804
The nucleus is an important target of signal transduction by growth factor receptors that stimulate mitogen-activated protein (MAP) kinases. We tested the hypothesis that MAP kinases have a signaling role within the nucleus by examining the effect of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aeae24a9b16d08309aaea30cf106a52f
https://doi.org/10.1016/s0021-9258(18)35834-4
https://doi.org/10.1016/s0021-9258(18)35834-4
Autor:
Tom Curran, Alpna Seth, Debra A. Latour, Cory Abate, Roger J. Davis, Ingrid C. Northwood, Elvira Alvarez, Fernando A. Gonzalez
Publikováno v:
Journal of Biological Chemistry. 266:15277-15285
A growth factor-stimulated (MAP2-related) protein kinase, ERT, that phosphorylates the epidermal growth factor receptor at Thr669 has been purified from KB human tumor cells by Northwood and co-workers (Northwood, I. C., Gonzalez, F. A., Wartmann, M.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b1618dbba9fca765a601560d1e7e645
https://doi.org/10.1016/s0021-9258(18)98613-8
https://doi.org/10.1016/s0021-9258(18)98613-8
Autor:
Jonathan R. Lamb, Alpna Seth, Lawrence J. Stern, Don C. Wiley, Richard D. Klausner, Tom H. M. Ottenhoff, Isaac Engel, Michael John Owen
Publikováno v:
Nature. 369(6478)
SUPERANTIGENS are proteins that in association with class II major histocompatibility complex (MHC)-bearing cells can stimulate vir-tually all T cells that express particular classes of the variable β-domains of the T-cell receptor (TCR)1. This mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274c8f493ec54755d31b1b7f374ef2aa
https://pubmed.ncbi.nlm.nih.gov/8183371
https://pubmed.ncbi.nlm.nih.gov/8183371
Publikováno v:
Cell. 72(2)
Treatment of cells with agents that stimulate the release of arachidonic acid causes increased serine phosphorylation and activation of cytosolic phospholipase A2 (cPLA2). Here we report that cPLA2 is a substrate for mitogen-activated protein (MAP) k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::484c701f186e3051f161e8fd1ba9dee6
https://pubmed.ncbi.nlm.nih.gov/8381049
https://pubmed.ncbi.nlm.nih.gov/8381049
Publikováno v:
The Journal of biological chemistry. 266(35)
The c-myc gene encodes a sequence-specific DNA-binding protein (c-Myc) that forms leucine zipper complexes and can act as a transcription factor. Growth factor stimulation of cells causes the phosphorylation of the c-Myc transcriptional activation do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbc5757d0c860fdb5e1ece8c1961d501
https://pubmed.ncbi.nlm.nih.gov/1748630
https://pubmed.ncbi.nlm.nih.gov/1748630
Publikováno v:
Scopus-Elsevier
ResearcherID
ResearcherID
It has been reported that the sequence Tyr20-X-Arg-Phe23 present within the cytoplasmic tail of the transferrin receptor may represent a tyrosine internalization signal (Collawn, J.F., Stangel, M., Kuhn, L.A., Esekogwu, V., Jing, S., Trowbridge, I.S.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b6d35576e0fcdea3562597a14406d2
http://www.scopus.com/inward/record.url?eid=2-s2.0-0025955191&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0025955191&partnerID=MN8TOARS
