A change in circulating chikungunya virus variant impacts Aedes aegypti vector competence and spatiotemporal distribution of disease in Malaysia.

Autor: Azman IK; Department of Medical Microbiology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia., Chan YF; Department of Medical Microbiology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia., Chua CL; Department of Medical Microbiology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia., Abd Mutalib ZA; Population and Demographic Statistics Division, Department of Statistics, Putrajaya, Malaysia., Dass SC; School of Mathematical & Computer Sciences, Heriot-Watt University Malaysia, Putrajaya, Malaysia., Gill BS; Institute for Medical Research, National Institutes of Health, Shah Alam, Malaysia., Ismail NH; Molecular Unit, Public Health Laboratory Kota Bharu, Kota Bharu, Malaysia., Jelip J; Vector-Borne Disease Section, Disease Control Division, Ministry of Health, Putrajaya, Malaysia., Wan MK; Vector-Borne Disease Section, Disease Control Division, Ministry of Health, Putrajaya, Malaysia., Lee WC; Department of Parasitology, Universiti Malaya, Kuala Lumpur, Malaysia.; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore., Vythilingam I; Department of Parasitology, Universiti Malaya, Kuala Lumpur, Malaysia., Alphey L; Department of Biology, University of York, York, United Kingdom.; York Biomedical Research Institute, University of York, York, United Kingdom., Sam IC; Department of Medical Microbiology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.

Publikováno v: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Oct 31; Vol. 18 (10), pp. e0012632. Date of Electronic Publication: 2024 Oct 31.

Expanding the transgene expression toolbox of the malaria vector Anopheles stephensi.

Autor: Southworth J; Department of Biosciences, Durham University, Durham, UK.; Arthropod Genetics, The Pirbright Institute, Pirbright, UK., Gonzalez E; Arthropod Genetics, The Pirbright Institute, Pirbright, UK., Nevard K; Arthropod Genetics, The Pirbright Institute, Pirbright, UK., Larrosa-Godall M; Arthropod Genetics, The Pirbright Institute, Pirbright, UK.; Department of Biology, University of York, York, UK., Alphey L; Arthropod Genetics, The Pirbright Institute, Pirbright, UK.; Department of Biology, University of York, York, UK.; York Biomedical Research Institute, University of York, York, UK., Anderson MAE; Arthropod Genetics, The Pirbright Institute, Pirbright, UK.; Department of Biology, University of York, York, UK.; York Biomedical Research Institute, University of York, York, UK.

Publikováno v: Insect molecular biology [Insect Mol Biol] 2024 Aug 11. Date of Electronic Publication: 2024 Aug 11.

A multiplexed, confinable CRISPR/Cas9 gene drive can propagate in caged Aedes aegypti populations.

Autor: Anderson MAE; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK.; The Department of Biology, University of York, Wentworth Way, York, YO10 5DD, UK., Gonzalez E; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK.; Animal and Plant Health Agency, Woodham Lane, Addlestone, Surrey, KT15 3NB, UK., Edgington MP; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK.; The Department of Biology, University of York, Wentworth Way, York, YO10 5DD, UK., Ang JXD; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK.; The Department of Biology, University of York, Wentworth Way, York, YO10 5DD, UK., Purusothaman DK; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK.; MRC-University of Glasgow Centre for Virus Research, Henry Wellcome Building, 464 Bearsden Road, Glasgow, G61 1QH, UK., Shackleford L; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK.; The Department of Biology, University of York, Wentworth Way, York, YO10 5DD, UK., Nevard K; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK., Verkuijl SAN; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK.; Department of Biology, University of Oxford, 11a Mansfield Road, Oxford, OX1 3SZ, UK., Harvey-Samuel T; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK., Leftwich PT; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK.; School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, Norfolk, NR4 7TJ, UK., Esvelt K; Media Laboratory, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Alphey L; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK. luke.alphey@york.ac.uk.; The Department of Biology, University of York, Wentworth Way, York, YO10 5DD, UK. luke.alphey@york.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2024 Jan 25; Vol. 15 (1), pp. 729. Date of Electronic Publication: 2024 Jan 25.

AePUb promoter length modulates gene expression in Aedes aegypti.

Autor: Anderson MAE; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK. michelle.anderson@york.ac.uk.; Department of Biology, University of York, Heslington, YO10 5DD, UK. michelle.anderson@york.ac.uk., Leftwich PT; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK.; School of Biological Sciences, University of East Anglia, Norwich, NR4 7TJ, UK., Wilson R; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK.; Department of Biology, University of York, Heslington, YO10 5DD, UK., Paladino LZC; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK., Basu S; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK.; Molecular Biology Team, R&D Division, Oxitec, Oxford, UK., Rooney S; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK.; Departments of Vector Biology and Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK., Adelman ZN; Department of Entomology, Texas A&M University, College Station, TX, USA., Alphey L; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK. luke.alphey@york.ac.uk.; Department of Biology, University of York, Heslington, YO10 5DD, UK. luke.alphey@york.ac.uk.

Publikováno v: Scientific reports [Sci Rep] 2023 Nov 21; Vol. 13 (1), pp. 20352. Date of Electronic Publication: 2023 Nov 21.

Optimizing CRE and PhiC31 mediated recombination in Aedes aegypti .

Autor: Carabajal Paladino LZ; Arthropod Genetics Group, The Pirbright Institute, Woking, United Kingdom., Wilson R; Arthropod Genetics Group, The Pirbright Institute, Woking, United Kingdom., Tng PYL; Arthropod Genetics Group, The Pirbright Institute, Woking, United Kingdom., Dhokiya V; Arthropod Genetics Group, The Pirbright Institute, Woking, United Kingdom., Keen E; Arthropod Genetics Group, The Pirbright Institute, Woking, United Kingdom., Cuber P; Arthropod Genetics Group, The Pirbright Institute, Woking, United Kingdom., Larner W; Arthropod Genetics Group, The Pirbright Institute, Woking, United Kingdom., Rooney S; Arthropod Genetics Group, The Pirbright Institute, Woking, United Kingdom., Nicholls M; Arthropod Genetics Group, The Pirbright Institute, Woking, United Kingdom., Uglow A; Arthropod Genetics Group, The Pirbright Institute, Woking, United Kingdom., Williams L; Arthropod Genetics Group, The Pirbright Institute, Woking, United Kingdom., Anderson MAE; Arthropod Genetics Group, The Pirbright Institute, Woking, United Kingdom., Basu S; Arthropod Genetics Group, The Pirbright Institute, Woking, United Kingdom., Leftwich PT; Arthropod Genetics Group, The Pirbright Institute, Woking, United Kingdom., Alphey L; Arthropod Genetics Group, The Pirbright Institute, Woking, United Kingdom.

Publikováno v: Frontiers in bioengineering and biotechnology [Front Bioeng Biotechnol] 2023 Sep 22; Vol. 11, pp. 1254863. Date of Electronic Publication: 2023 Sep 22 (Print Publication: 2023).