Zobrazeno 1 - 10
of 13 362
pro vyhledávání: '"Alpha-Glucosidase"'
Autor:
Giancarlo Parenti, Simona Fecarotta, Marianna Alagia, Federica Attaianese, Alessandra Verde, Antonietta Tarallo, Vincenza Gragnaniello, Athanasia Ziagaki, Maria Jose’ Guimaraes, Patricio Aguiar, Andreas Hahn, Olga Azevedo, Maria Alice Donati, Beata Kiec-Wilk, Maurizio Scarpa, Nadine A. M. E. van der Beek, Mireja Del Toro Riera, Dominique P. Germain, Hidde Huidekoper, Johanna M. P. van den Hout, Ans T. van der Ploeg, and the MetabERN Subnetwork for Lysosomal Disorders
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-23 (2024)
Abstract Clinical pathway recommendations (CPR) are based on existing guidelines and deliver a short overview on how to deal with a specific diagnosis, resulting therapy and follow-up. In this paper we propose a methodology for developing CPRs for Po
Externí odkaz:
https://doaj.org/article/ef4620eaa39f4a08bbe3b14b878a0993
Publikováno v:
罕见病研究, Vol 3, Iss 3, Pp 318-325 (2024)
ObjectiveTo investigate the clinical features and genetic characteristics of patients with late-onset Pompe disease(LOPD).MethodsA total of 13 patients diagnosed with LOPD in the First Affiliated Hospital of Zhejiang University School of Medicine fro
Externí odkaz:
https://doaj.org/article/7487c38618fc40b497f84eab5aefc6b0
Publikováno v:
Jurnal Kimia Sains dan Aplikasi, Vol 27, Iss 7, Pp 316-327 (2024)
Diabetes mellitus (DM) is a chronic metabolic disorder posing a significant health risk. Effective treatments are continually sought. Coumarin derivatives with oxime ester groups have shown potential as antidiabetic agents by inhibiting the α-glucos
Externí odkaz:
https://doaj.org/article/67383bdd7cc74f56aef6117283c8f3cd
Autor:
Sandra Milena Castellar-Leones, Fernando Ortiz-Corredor, Daniel Manrique-Hernández, Diana Sánchez-Peñarete, Edicson Ruiz-Ospina, Diana Soto-Peña, Cristian Correa-Arrieta
Publikováno v:
Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-5 (2024)
Abstract Background Pompe disease, a rare autosomal recessive disorder caused by acid alpha-glucosidase deficiency, results in progressive glycogen accumulation and multisystem dysfunction. Enzyme replacement therapy with recombinant human acid alpha
Externí odkaz:
https://doaj.org/article/dea8e376910644618a67679fbc33812e
Autor:
Niels B Dalsgaard, Lærke S Gasbjerg, Laura S Hansen, Dennis S Nielsen, Torben S Rasmussen, Filip K Knop
Publikováno v:
Endocrine Connections, Vol 13, Iss 7, Pp 1-7 (2024)
Aim: The alpha-glucosidase inhibitor acarbose is approved for the treatment of type 2 diabetes (T2D). It acts in the lumen of the gut by reducing intestinal hydrolysis and absorption of ingested carbohydrates. This reduces postprandial blood glucose
Externí odkaz:
https://doaj.org/article/fc39470700c2487790ef240db845be3a
Publikováno v:
Bibechana, Vol 21, Iss 3 (2024)
Beta vulgaris is an annual crop grown for its edible roots and leaves. It is traditionally used for the treatment of diabetes, cancer, obesity, heart problems, kidney problems, and liver diseases. The present work is centered on the phytochemical ana
Externí odkaz:
https://doaj.org/article/bba9cfec15c741068cca4ef742c61134
Autor:
Tumelo Akapelwa Muyenga, Samuel K. Dominion Bamitale, Dan Kibuule, Simbarashe Sithole, Stanley Mukanganyama, Carlen Rudolph, Luanne Venables, Anna C. Hattingh, Maryna van de Venter, Christian Chinyere Ezeala
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Diabetes affects 75% of people in low-income countries, where conventional drugs like metformin are available, but newer drugs like alpha-glucosidase inhibitors are not accessible to most Southern African patients. Aim To evaluate
Externí odkaz:
https://doaj.org/article/4bd815052ae5488597a5fd061eb9de69
Autor:
Atalanti Christou, Constantina Stavrou, Christodoulos Michael, George Botsaris, Vlasios Goulas
Publikováno v:
Microbiology Research, Vol 15, Iss 2, Pp 926-942 (2024)
Plants possess endless structural and chemical diversity, which is peerless with any synthetic library of small biomolecules, inspiring novel drug discovery. Plants are widely applied to encounter global health challenges such as antimicrobial resist
Externí odkaz:
https://doaj.org/article/9324357d5c2a48fcb3309ad60ef1b0cc
Publikováno v:
Journal of Pharmacy and Bioallied Sciences, Vol 16, Iss 6, Pp 1291-1294 (2024)
Diabetes mellitus is a persistent metabolic condition marked by elevated blood glucose levels due to compromised insulin secretion or functionality. The search for natural antidiabetic agents has gained attention due to their potential effectiveness
Externí odkaz:
https://doaj.org/article/14d348c31bfe4b65b47c8bc5f25a0a2c
Publikováno v:
Кубанский научный медицинский вестник, Vol 31, Iss 2, Pp 107-117 (2024)
Background. Infantile-onset form of Pompe disease (IOPD) comprises a progressive and fatal disease in the absence of pathogenetic treatment. Enzyme replacement therapy using biologically active recombinant human alglucosidase alfa is considered as a
Externí odkaz:
https://doaj.org/article/324f076bd1ad4835bfd9499f7e27858c