Zobrazeno 1 - 10
of 248
pro vyhledávání: '"Alpha S Yap"'
Autor:
Hiroko Katsuno-Kambe, Jessica L Teo, Robert J Ju, James Hudson, Samantha J Stehbens, Alpha S Yap
Publikováno v:
eLife, Vol 10 (2021)
Epithelial networks are commonly generated by processes where multicellular aggregates elongate and branch. Here, we focus on understanding cellular mechanisms for elongation using an organotypic culture system as a model of mammary epithelial anlage
Externí odkaz:
https://doaj.org/article/f8d14b1296864762afc74d5ceeffe548
Autor:
Rashmi Priya, Guillermo A Gomez, Srikanth Budnar, Bipul R Acharya, Andras Czirok, Alpha S Yap, Zoltan Neufeld
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 3, p e1005411 (2017)
Mechanical coherence of cell layers is essential for epithelia to function as tissue barriers and to control active tissue dynamics during morphogenesis. RhoA signaling at adherens junctions plays a key role in this process by coupling cadherin-based
Externí odkaz:
https://doaj.org/article/3e090f98abff4b48a5eb1481ba64b9e5
Autor:
Natasha Chaudhary, Guillermo A Gomez, Mark T Howes, Harriet P Lo, Kerrie-Ann McMahon, James A Rae, Nicole L Schieber, Michelle M Hill, Katharina Gaus, Alpha S Yap, Robert G Parton
Publikováno v:
PLoS Biology, Vol 12, Iss 4, p e1001832 (2014)
Several studies have suggested crosstalk between different clathrin-independent endocytic pathways. However, the molecular mechanisms and functional relevance of these interactions are unclear. Caveolins and cavins are crucial components of caveolae,
Externí odkaz:
https://doaj.org/article/b65d5687fee24cb6b8b50d7a8d75d575
Autor:
Sharon Tran, Juliani Juliani, Tiffany J. Harris, Marco Evangelista, Julian Ratcliffe, Sarah L. Ellis, David Baloyan, Camilla M. Reehorst, Rebecca Nightingale, Ian Y. Luk, Laura J. Jenkins, Sonia Ghilas, Marina H. Yakou, Chantelle Inguanti, Chad Johnson, Michael Buchert, James C. Lee, Peter De Cruz, Kinga Duszyc, Paul A. Gleeson, Benjamin T. Kile, Lisa A. Mielke, Alpha S. Yap, John M. Mariadason, W. Douglas Fairlie, Erinna F. Lee
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Autophagy-related genes have been closely associated with intestinal homeostasis. BECLIN1 is a component of Class III phosphatidylinositol 3-kinase complexes that orchestrate autophagy initiation and endocytic trafficking. Here we show intes
Externí odkaz:
https://doaj.org/article/fc863b699bb647f5926120d1c9e15000
Autor:
Michael Smutny, Selwin K Wu, Guillermo A Gomez, Sabine Mangold, Alpha S Yap, Nicholas A Hamilton
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22458 (2011)
The zonula adherens (ZA) of epithelial cells is a site of cell-cell adhesion where cellular forces are exerted and resisted. Increasing evidence indicates that E-cadherin adhesion molecules at the ZA serve to sense force applied on the junctions and
Externí odkaz:
https://doaj.org/article/fd20dcb6bea4444c8ad93a60fc2a7eb7
Autor:
Jack T H Wang, Markus C Kerr, Seetha Karunaratne, Angela Jeanes, Alpha S Yap, Rohan D Teasdale
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13763 (2010)
BackgroundMacropinocytosis is an actin-driven endocytic process, whereby membrane ruffles fold back onto the plasma membrane to form large (>0.2 µm in diameter) endocytic organelles called macropinosomes. Relative to other endocytic pathways, little
Externí odkaz:
https://doaj.org/article/90cddefc1f9142f5ad4eea4b89b19013
Publikováno v:
PLoS ONE, Vol 3, Iss 9, p e3254 (2008)
Previous studies have indicated that Epstein-Barr virus (EBV) can modulate the Wnt pathway in virus-infected cells and this effect is mediated by EBV-encoded oncogene latent membrane protein 1 (LMP1). Here we have reassessed the role of LMP1 in regul
Externí odkaz:
https://doaj.org/article/0584fcbf927441c3b92e408c20bfffd8
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 102077- (2023)
Summary: Extracellular matrix (ECM) provides fundamental support for epithelial tissues and controls cell function. The chemistry and mechanical properties of ECM components, including stiffness, elasticity, and fibrillar organization, influence epit
Externí odkaz:
https://doaj.org/article/1d74e25da1f64ad0ada5619b32ea463e
Autor:
Ygal Haupt, Robin Anderson, Ora Bernard, Stephen Fox, Alpha S. Yap, Yong-Hui Jiang, Yarra Levav-Cohen, Brendon Monahan, Cameron Johnstone, Mark Bishton, Elena A. Takano, Siddhartha Deb, Franco Caramia, Sherene Loi, Alexandra Rizzitelli, Nathan Godde, Ai-Leen Chan, Sue Haupt, Mariam Mansour
supplemental figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7ab8adad3aa2595a3e8217cefd229b
https://doi.org/10.1158/0008-5472.22410044.v1
https://doi.org/10.1158/0008-5472.22410044.v1
Autor:
Ygal Haupt, Robin Anderson, Ora Bernard, Stephen Fox, Alpha S. Yap, Yong-Hui Jiang, Yarra Levav-Cohen, Brendon Monahan, Cameron Johnstone, Mark Bishton, Elena A. Takano, Siddhartha Deb, Franco Caramia, Sherene Loi, Alexandra Rizzitelli, Nathan Godde, Ai-Leen Chan, Sue Haupt, Mariam Mansour
legends for supplemantry figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c8746b66f2a43a7c9f0e989a0730c9e
https://doi.org/10.1158/0008-5472.22410038.v1
https://doi.org/10.1158/0008-5472.22410038.v1