Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alpha Lee"'
Autor:
Zhaojun Li, Hope Bretscher, Yunwei Zhang, Géraud Delport, James Xiao, Alpha Lee, Samuel D. Stranks, Akshay Rao
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
The low photoluminescence of monolayer transition metal disulfides remains a challenge for their optoelectronic application. Here the authors present an effective and green method to enhance the photoluminescence of monolayer MoS2 and WS2, and a deta
Externí odkaz:
https://doaj.org/article/5db2bf44d5f646e3a1f025cb45db1e54
Autor:
Emma King-Smith, Felix Faber, Usa Reilly, Anton Sinitskiy, Qingyi Yang, Bo Liu, Dennis Hyek, Alpha Lee
Structural diversification of lead molecules is a key component of drug discovery to explore chemical space. Late stage functionalizations (LSFs) are versatile methodologies capable of installing functional handles on richly decorated intermediates t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3dec14f4b80ad9edd74d1765f524d38
https://doi.org/10.21203/rs.3.rs-2741247/v1
https://doi.org/10.21203/rs.3.rs-2741247/v1
Autor:
Emma King-Smith, Simon Berritt, Louise Bernier, Xinjun Hou, Jacquelyn Klug-McLeod, Jason Mustakis, Neal Sach, Joseph Tucker, Qingyi Yang, Roger Howard, Alpha Lee
High-throughput experimentation (HTE) has the potential to improve our understanding of organic chemistry by systematically interrogating reactivity across diverse chemical spaces. Notable bottlenecks include few publicly available large-scale datase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe10aa2abc0085ed30e2d72972a8424
https://doi.org/10.21203/rs.3.rs-2262919/v1
https://doi.org/10.21203/rs.3.rs-2262919/v1
Autor:
Ruben Sanchez-Garcia, Dávid Havasi, Gergely Takács, Matthew C. Robinson, Alpha Lee, Frank von Delft, Charlotte M. Deane
Compound availability is a critical property for design prioritization across the drug discovery pipeline. Historically, and despite their multiple limitations, compound-oriented synthetic accessibility scores have been used as proxies for this probl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::279e2482bc589687266a72bad22f13b8
https://doi.org/10.26434/chemrxiv-2022-gvk2k-v6
https://doi.org/10.26434/chemrxiv-2022-gvk2k-v6
Autor:
Alpha Lee
Publikováno v:
Journal of Biological Chemistry. 299:103456
Autor:
Ruben Sanchez-Garcia, Dávid Havasi, Gergely Takács, Matthew C. Robinson, Alpha Lee, Frank von Delft, Charlotte M. Deane
Compound availability is a critical property for design prioritization across the drug discovery pipeline. Historically, and despite its multiple limitations, compound-oriented synthetic accessibility scores have been used as proxies for this problem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8a49dcf751251f573d4b2bbc6cdb576
https://doi.org/10.26434/chemrxiv-2022-gvk2k
https://doi.org/10.26434/chemrxiv-2022-gvk2k
The COVID-19 pandemic is a stark reminder that a barren global antiviral pipeline has grave humanitarian consequences. Future pandemics could be prevented by accessible, easily deployable broad-spectrum oral antivirals and open knowledge bases that d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b7c6e31fcc5eff3442a22094ef899e9
https://doi.org/10.33774/chemrxiv-2021-585ks-v2
https://doi.org/10.33774/chemrxiv-2021-585ks-v2
Publikováno v:
ECS Meeting Abstracts. :521-521
Accurate forecasting of Li-ion battery performance is important for easing consumer concerns about the safety and reliability of electric vehicles. Most research on battery health prognostics focuses on the R&D setting where cells are subjected to th
Autor:
Frank, von Delft, Mark, Calmiano, John, Chodera, Ed, Griffen, Alpha, Lee, Nir, London, Tatiana, Matviuk, Ben, Perry, Matt, Robinson, Annette, von Delft
Publikováno v:
Nature. 594(7863)
Herein we provide a living summary of the data generated during the COVID Moonshot project focused on the development of SARS-CoV-2 main protease (Mpro) inhibitors. Our approach uniquely combines crowdsourced medicinal chemistry insights with high th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bba749a7ef9eaed19818bb2c63016fe
https://doi.org/10.26434/chemrxiv.13158218
https://doi.org/10.26434/chemrxiv.13158218