Dissolving Lignin in Water through Enzymatic Sulfation with Aryl Sulfotransferase

Autor: Gadi Rothenberg, Ron Wever, Aloysius F. Hartog, Pepijn Prinsen, Anand Narani

Publikováno v: ChemSusChem, 10(10), 2267-2273. Wiley-VCH Verlag

We introduce the concept of using site-specific sulfation of various lignins for increasing their aqueous solubility and thereby their processability. Using p-nitrophenylsulfate as a sulfate source and an aryl sulfotransferase enzyme as catalyst, lig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a00cbfd5745b8f7fefb19b54f9d3e9da
https://doi.org/10.1002/cssc.201700376

Effects of rapamycin and curcumin treatment on the development of epilepsy after electrically induced status epilepticus in rats

Autor: Jan A. Gorter, Wytse J. Wadman, Eleonora Aronica, Lars E. Borm, Lieneke Kooijman, Erwin A. van Vliet, Aloysius F. Hartog, Cato M. Drion

Publikováno v: Epilepsia, 57(5), 688-697. Wiley-Blackwell

OBJECTIVE: Inhibition of the mammalian target of rapamycin (mTOR) pathway has been suggested as a possible antiepileptogenic strategy in temporal lobe epilepsy (TLE). Here we aim to elucidate whether mTOR inhibition has antiepileptogenic and/or antis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3c52e65d7356a3c32e6684f70d90b7
https://dare.uva.nl/personal/pure/en/publications/effects-of-rapamycin-and-curcumin-treatment-on-the-development-of-epilepsy-after-electrically-induced-status-epilepticus-in-rats(1dcd4f29-e8ec-430a-866e-89d012e4060a).html

Substrate engineering and its synthetic utility in the sulfation of primary aliphatic alcohol groups by a bacterial arylsulfotransferase

Autor: Ron Wever, Aloysius F. Hartog

Publikováno v: Advanced Synthesis & Catalysis, 357(12), 2629-2632. Wiley-VCH Verlag

The use of substrate engineering allowed the enzymatic sulfation by an arylsulfotransferase from Desulfitobacterium hafniense of a number of carbohydrate derivatives. Specific sulfation of carbohydrates chemically or enzymatically is notoriously diff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2307e558c65d0941c4ffe188f33d02d
https://doi.org/10.1002/adsc.201500482

Enzymatic Sulfation of Phenolic Hydroxy Groups of Various Plant Metabolites by an Arylsulfotransferase

Autor: Menzo Kircz, Rabab El Morabet, Arthur Marais, Ron Wever, Aloysius F. Hartog, Michael A. van der Horst

Publikováno v: European Journal of Organic Chemistry. 2015:534-541

The bacterial arylsulfate sulfotransferase (AST) from Desulfitobacterium hafniense was used as a catalytic tool to derivatize poorly sol. arom. compds. (polyphenols)​. As examples, we sulfated the natural occurring compds. p-​coumaric acid, 6-​

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d7a6fc6857f3de839d7a475709b1af1
https://doi.org/10.1002/ejoc.201402875

Antimicrobial effect of a modified vanadium chloroperoxidase on Enterococcus faecalis biofilms at root canal pH

Autor: Aloysius F. Hartog, Paul R. Wesselink, Michel A. Hoogenkamp, Aleksandra Bury, I.F. Persoon, Wim Crielaard, Ron Wever

Publikováno v: Persoon, I F, Hoogenkamp, M A, Bury, A, Wesselink, P R, Hartog, A F, Wever, R & Crielaard, W 2013, ' Antimicrobial effect of a modified vanadium chloroperoxidase on Enterococcus faecalis biofilms at root canal pH ', The Journal of Endodontics, vol. 39, no. 8, pp. 1035-1038 . https://doi.org/10.1016/j.joen.2013.04.038
The Journal of Endodontics, 39(8), 1035-1038. Elsevier Inc.
The Journal of Endodontics, 39(8), 1035-1038. Elsevier

IntroductionPrevious research showed an antimicrobial effect of vanadium chloroperoxidase (VCPO) on in vitro Enterococcus faecalis biofilms. The current study aimed to optimize the use of this enzyme at the root canal pH using a modified VCPO (mVCPO)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39403bfe19ca7a3be725b515e1591a21
https://doi.org/10.1016/j.joen.2013.04.038