Unraveling the therapeutic potential of Satureja nabateorum extract: inducing apoptosis and cell cycle arrest through p53, Bax/Bcl-2, and caspase-3 pathways in human malignant cell lines, with in silico insights.

Autor: Huwaimel B; Department of Pharmaceutical Chemistry, College of Pharmacy, University of Hail, Hail, Saudi Arabia.; Medical and Diagnostic Research Centre, University of Hail, Hail, Saudi Arabia., Mohammed HA; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Qassim University, Buraydah, Saudi Arabia., Elkashlan AM; Department of Biochemistry, Faculty of Pharmacy, University of Sadat City, Sadat City, Egypt., Alnajjar R; CADD Uunit, PharmD, Faculty of Pharmacy, Libyan International Medical University, Benghazi, Libya.; Department of Chemistry, University of Cape Town, Rondebosch, South Africa., Altamimi OA; Department of Pharmaceutical Chemistry, College of Pharmacy, University of Hail, Hail, Saudi Arabia., Alorainan MM; Department of Pharmaceutical Chemistry, College of Pharmacy, University of Hail, Hail, Saudi Arabia., Altuwayhir MK; Department of Pharmaceutical Chemistry, College of Pharmacy, University of Hail, Hail, Saudi Arabia., Algharby SF; Department of Pharmaceutical Chemistry, College of Pharmacy, University of Hail, Hail, Saudi Arabia., Almahmoud SA; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Qassim University, Buraydah, Saudi Arabia., Abouzied AS; Department of Pharmaceutical Chemistry, College of Pharmacy, University of Hail, Hail, Saudi Arabia.; Medical and Diagnostic Research Centre, University of Hail, Hail, Saudi Arabia.; Department of Pharmaceutical Chemistry, National Organization for Drug Control and Research (NODCAR), Giza, Egypt.

Publikováno v: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2024 Oct 26, pp. 1-18. Date of Electronic Publication: 2024 Oct 26.