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Akademický článek

Physcion Protects Against Ethanol-Induced Liver Injury by Reprogramming of Circadian Clock

Autor: Youli Yao, Along Zuo, Qiyu Deng, Shikang Liu, Tianying Zhan, Maolin Wang, Haidong Xu, Junxian Ma, Yingying Zhao

Publikováno v: Frontiers in Pharmacology, Vol 11 (2020)

The circadian clock plays a key role in our daily physiology and metabolism. Alcohol consumption disrupts the circadian rhythm of metabolic genes in the liver; however, the potential contribution of circadian clock modulation to alcoholic liver disea

Externí odkaz: https://doaj.org/article/41b4b48b9d074228b068e69d14f4a827

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Akademický článek

Noninvasive 40-Hz Light Flicker Rescues Circadian Behavior and Abnormal Lipid Metabolism Induced by Acute Ethanol Exposure via Improving SIRT1 and the Circadian Clock in the Liver-Brain Axis

Autor: Youli Yao, Wenjiang Zhang, Ruibo Ming, Qiyu Deng, Along Zuo, Shengli Zhang, Ying Ying, Yingying Zhao, Junxian Ma

Publikováno v: Frontiers in Pharmacology, Vol 11 (2020)

Sirtuin 1 (SIRT1) is a protein deacetylase with important cellular functions, as it regulates numerous processes, including the circadian rhythm in peripheral tissues. Efforts are ongoing to reveal how Sirt1 can be used to treat diseases, such as alc

Externí odkaz: https://doaj.org/article/e5b258ca240b4e5996310bc88fb4dc96

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Qianjin Wenwu decoction suppresses renal interstitial fibrosis by enhancing the degradation of extracellular matrix in mice with unilateral ureteral obstruction

Autor: Chengshan JIN, Xiaotian WU, Yue YOU, Yuing WANG, Jing WU, Along ZUO, Yan ZHENG, Jianpeng GUO

Publikováno v: Chinese Journal of Natural Medicines. 21:253-262

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a0146def9ebe6f83b2fbfafd5364db2f
https://doi.org/10.1016/s1875-5364(23)60434-0

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Bioadhesion design of hydrogels: adhesion strategies and evaluation methods for biological interfaces

Autor: Huanhui Wang, Xuena Li, Maocheng Li, Shuangqing Wang, Along Zuo, Jianpeng Guo

Publikováno v: Journal of Adhesion Science and Technology. 37:335-369

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::382ba9a1f1f417e910a113c6a3b6acc7
https://doi.org/10.1080/01694243.2021.2020502

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A method for evaluating drug penetration and absorption through isolated buccal mucosa with highly accuracy and reproducibility

Autor: Shuangqing Wang, Lei Liu, Saige Meng, Yuling Wang, Daofeng Liu, Zhonggao Gao, Along Zuo, Jianpeng Guo

Publikováno v: Drug delivery and translational research. 12(11)

The purpose of the project is to establish a standardized operation method of the in vitro permeability model to maximize mucosal integrity and viability. The model drug lidocaine permeability, 20 kDa fluorescein isothiocyanate-dextran, HE staining,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e4b39e2de5ab96304e4edc4ccc32bed
https://pubmed.ncbi.nlm.nih.gov/35349106

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Docetaxel-Loaded PAMAM-Based Poly (γ-benzyl-L-glutamate)–b- D -α - Tocopheryl Polyethylene Glycol 1000 Succinate Nanoparticles in Human Breast Cancer And Human Cervical Cancer therapy

Autor: Yatao Yang, Gan Liu, Yingying Zhao, Ying Ying, Xiaomei Wang, Junxian Ma, Guimiao Lin, Lin Mei, Xiaoyan Huang, Along Zuo, Xianxiong Chen, Xinsheng Shu, Yingting Wang

Publikováno v: Journal of Microencapsulation. :1-33

Taxane-based chemotherapy-loaded drug delivery systems have great potential for cancer treatment. The docetaxel (DTX)-loaded PAMAM-based poly (γ-benzyl-l-glutamate)-b-d-α-tocopheryl polyethylene glycol 1000 succinate (PAM-PBLG-b-TPGS) nanoparticles

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7764eb05e949cac817ccb68aab6fed08
https://doi.org/10.1080/02652048.2019.1654002

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Preparation, in vitro and in vivo evaluation of chitosan-sodium alginate-ethyl cellulose polyelectrolyte film as a novel buccal mucosal delivery vehicle

Autor: Mingxin Li, Jianpeng Guo, Shuangqing Wang, Zhonggao Gao, Lei Liu, Along Zuo

Publikováno v: European Journal of Pharmaceutical Sciences. 168:106085

This paper describes the development of a film comprising chitosan (CS), sodium alginate (SA), and ethyl cellulose (EC) for buccal mucosal administration. A film of CS-SA unidirectional release drug-containing water-repellent layer EC was produced by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039c78c05960eeb4f23be30e3c81aa45
https://doi.org/10.1016/j.ejps.2021.106085

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Types and evaluation of in vitro penetration models for buccal mucosal delivery

Autor: Jianpeng Guo, Along Zuo, Shuangqing Wang

Publikováno v: Journal of Drug Delivery Science and Technology. 61:102122

Oral buccal mucosal delivery has the advantage of avoiding gastrointestinal drug degradation, reducing hepatic firstpass effects, and improving patient compliance. In recent years, it is becoming a drug delivery route that researchers have paid atten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14627269c5e55dafb609076df9a7d866
https://doi.org/10.1016/j.jddst.2020.102122

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Understanding the effect of anthocyanin extracted from Lonicera caerulea L. on alcoholic hepatosteatosis

Autor: Shuangqing Wang, Lei Liu, Youli Yao, Jianpeng Guo, Along Zuo

Publikováno v: Biomedicine & Pharmacotherapy, Vol 117, Iss, Pp-(2019)

Liver inflammation and excessive accumulation of lipids play a critical role in alcoholic liver diseases (ALD) pathogenesis. Plant polyphenols are widely used to prevent toxic liver damage. The anthocyanin from Lonicera caerulea L. was extracted and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1c2d3031318ee909e1f77e4433ea45
https://doi.org/10.1016/j.biopha.2019.109087

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