Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alondra Schweizer Burguete"'
Autor:
Alondra Schweizer Burguete, Sandra Almeida, Fen-Biao Gao, Robert Kalb, Michael R Akins, Nancy M Bonini
Publikováno v:
eLife, Vol 4 (2015)
Microsatellite expansions are the leading cause of numerous neurodegenerative disorders. Here we demonstrate that GGGGCC and CAG microsatellite repeat RNAs associated with C9orf72 in amyotrophic lateral sclerosis/frontotemporal dementia and with poly
Externí odkaz:
https://doaj.org/article/bd92b12218bd45eb980c3adf35682bbb
Publikováno v:
Cell. 132:286-298
SummaryGCC185 is a large coiled-coil protein at the trans Golgi network that is required for receipt of transport vesicles inbound from late endosomes and for anchoring noncentrosomal microtubules that emanate from the Golgi. Here, we demonstrate tha
Publikováno v:
Nature Methods. 1:55-60
We present a new method for the rapid identification of amino acid residues that contribute to protein-protein interfaces. Tail-interacting protein of 47 kDa (TIP47) binds Rab9 GTPase and the cytoplasmic domains of mannose 6-phosphate receptors and i
Publikováno v:
Hereditas. 133:217-228
The concept of recent hominoid divergences has been a mainstay in molecular primatology since the 1970's. However, the ages allocated to the calibration points used to establish these divergence times and the estimates resulting from their applicatio
Autor:
Michelle J. Holder, Anita Chamba, John D. Pound, Alondra Schweizer Burguete, Aristides G. Eliopoulos, Anita Challa, Lawrence S. Young, Richard J. Armitage, Christopher D. Gregory, Gillian Grafton, Hector Martinez-Valdez, John R. Gordon
Publikováno v:
Blood. 99:3411-3418
Population size is governed through cells reacting to a variety of intrinsic and extrinsic cues. Tumors, while liberated from many of the homeostatic constraints placed on physiologic counterparts, can nonetheless remain subject to both social and en
Autor:
Alondra Schweizer Burguete, Melker Göransson, Pierre Åman, Anita Olofsson, Sofia Thelin-Järnum
Publikováno v:
International Journal of Cancer. 97:446-450
CHOP in 12q13, also called GADD153 or DDIT3, encodes a transcription factor of the C/EBP type. As a result of t(12;16) translocations, CHOP is rearranged and fused to TLS in 16p11 in about 90% of myxoid liposarcomas/round cell liposarcomas (MLS/RCLS)
Autor:
Ian G. Ganley, Khambhampaty Sridevi, Ryan M. Nottingham, Suzanne R. Pfeffer, Jonathan V. Reddy, Alondra Schweizer Burguete
Publikováno v:
Molecular biology of the cell. 17(10)
Mannose 6-phosphate receptors (MPRs) deliver newly synthesized lysosomal enzymes to endosomes and then recycle to the Golgi. MPR recycling requires Rab9 GTPase; Rab9 recruits the cytosolic adaptor TIP47 and enhances its ability to bind to MPR cytopla
Publikováno v:
Methods in enzymology. 403
TIP47 (tail interacting protein of 47 kDa) is a cytosolic protein that is essential for the transport of mannose 6-phosphate receptors (MPRs) from endosomes to the trans-Golgi. This protein is recruited from the cytosol onto the surface of late endos
Publikováno v:
Current Protocols in Protein Science
This unit describes a rapid and efficient method to screen a polypeptide for amino acid residues that contribute to protein-protein interaction interfaces. Cysteine residues are introduced as positional probes in a protein at random by co-expression