Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alona Sarver"'
Autor:
Liat Buzaglo-Azriel, Yael Kuperman, Michael Tsoory, Yehudit Zaltsman, Liat Shachnai, Smadar Levin Zaidman, Elad Bassat, Inbal Michailovici, Alona Sarver, Eldad Tzahor, Michal Haran, Cecile Vernochet, Atan Gross
Publikováno v:
Cell Reports, Vol 18, Iss 5, Pp 1335-1336 (2017)
Externí odkaz:
https://doaj.org/article/cee4a0a2154141b08337a95fe87f1f32
Autor:
Ayelet Erez, Eytan Ruppin, Igor Ulitsky, Sandesh C.S. Nagamani, Yair Anikster, Raya Eilam, Ben Pode-Shakked, Yehudit Zaltsman-Amir, Keren Bahar Halpern, Erez Persi, Sivan Galai, Noa Stettner, Julia Frug, Alona Sarver, Rom Keshet, Joo Sang Lee, Lital Adler, Shiran Rabinovich, Adi Jacob, Odeya Boukobza Assayag, Omer Goldman, Alon Silberman
Supplementary Figures 1-5 further support our findings regarding the contribution to the maintenance of intracellular pH for ASS1 downregulated cancer cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bf590f6c6dae26b958754b6195138c9
https://doi.org/10.1158/0008-5472.22422482
https://doi.org/10.1158/0008-5472.22422482
Autor:
Ayelet Erez, Eytan Ruppin, Igor Ulitsky, Sandesh C.S. Nagamani, Yair Anikster, Raya Eilam, Ben Pode-Shakked, Yehudit Zaltsman-Amir, Keren Bahar Halpern, Erez Persi, Sivan Galai, Noa Stettner, Julia Frug, Alona Sarver, Rom Keshet, Joo Sang Lee, Lital Adler, Shiran Rabinovich, Adi Jacob, Odeya Boukobza Assayag, Omer Goldman, Alon Silberman
Downregulation of the urea cycle enzyme argininosuccinate synthase (ASS1) by either promoter methylation or by HIF1α is associated with increased metastasis and poor prognosis in multiple cancers. We have previously shown that in normoxic conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a0c71bc872afa3968a802eb42fd39f4
https://doi.org/10.1158/0008-5472.c.6511238.v1
https://doi.org/10.1158/0008-5472.c.6511238.v1
Autor:
Alexander Brandis, Julia Frug, Raya Eilam, Sandesh C.S. Nagamani, Muralidhar H. Premkumar, Niv Zmora, Nicola Brunetti-Pierri, Alon Silberman, Ram Mazkereth, Meirav Pevsner-Fischer, Alona Sarver, Noa Stettner, Diego di Bernardo, Shiri Gur-Cohen, Alon Harmelin, Steffen Jung, Ayelet Erez, Narin N. Carmel-Neiderman, Chava Rosen, Inbal E. Biton, Keren Bahar Halpern, Gillian Dank, Biana Bernshtein
Publikováno v:
Cell Reports
Summary Nitric oxide (NO) plays an established role in numerous physiological and pathological processes, but the specific cellular sources of NO in disease pathogenesis remain unclear, preventing the implementation of NO-related therapy. Argininosuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb3bb1a5f265f9ec17c0205634339f3
http://europepmc.org/articles/PMC5976577
http://europepmc.org/articles/PMC5976577
Autor:
Lital Adler, Noa Stettner, Shani Agron, David Dimmock, Shalev Itzkovitz, Daniel Helbling, Qin Sun, Alexander Brandis, Ayelet Erez, Eytan Ruppin, Alona Sarver, Shiran Rabinovich, Stanley H. Korman, Sandesh C.S. Nagamani, Keren Yizhak, Igor Ulitsky, Alon Silberman
Publikováno v:
Nature
Cancer cells hijack and remodel existing metabolic pathways for their benefit. Argininosuccinate synthase (ASS1) is a urea cycle enzyme that is essential in the conversion of nitrogen from ammonia and aspartate to urea. A decrease in nitrogen flux th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7e8de51e33226e8df183a26a94d9188
https://doi.org/10.1038/nature15529
https://doi.org/10.1038/nature15529
Autor:
Atan Gross, Yehudit Zaltsman, Michael Tsoory, Smadar Levin Zaidman, Eldad Tzahor, Yael Kuperman, Elad Bassat, Liat Buzaglo-Azriel, Michal Haran, Cecile Vernochet, Liat Shachnai, Inbal Michailovici, Alona Sarver
Publikováno v:
Cell Reports, Vol 18, Iss 5, Pp 1335-1336 (2017)
SummaryMitochondrial carrier homolog 2 (MTCH2) is a repressor of mitochondrial oxidative phosphorylation (OXPHOS), and its locus is associated with increased BMI in humans. Here, we demonstrate that mice deficient in muscle MTCH2 are protected from d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62156b697135ed8b8adbd87ecf1f7314
http://www.sciencedirect.com/science/article/pii/S2211124717301018
http://www.sciencedirect.com/science/article/pii/S2211124717301018
Autor:
Erez Persi, Ayelet Erez, Keren Bahar Halpern, Raya Eilam, Joo Sang Lee, Shiran Limanovich, Eytan Ruppin, Alona Sarver, Sandesh C.S. Nagamani, Yair Anikster, Alon Silberman, Rom Keshet, Adi Jacob, Igor Ulitsky, Alexander Brandis, Ben Pode, Odeya Boukobza
Publikováno v:
Cancer Research. 77:4987-4987
”pH gradient reversal”, namely the alkalinization of intracellular pH (pHi) and acidification of extracellular pH (pHe), is a unique phenotype of cancer cells which enable cancer survival, migration and invasion. Hence, not surprisingly, pH gradi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c02782f011591f70db5ae0d767093961
https://doi.org/10.1158/1538-7445.am2017-4987
https://doi.org/10.1158/1538-7445.am2017-4987