Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Alon Silberman"'
Autor:
Amir Bahat, Andres Goldman, Yehudit Zaltsman, Dilshad H. Khan, Coral Halperin, Emmanuel Amzallag, Vladislav Krupalnik, Michael Mullokandov, Alon Silberman, Ayelet Erez, Aaron D. Schimmer, Jacob H. Hanna, Atan Gross
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Reprogramming of mitochondria metabolism occurs during naïve to primed pluripotency differentiation in mouse embryonic stem cells (ESCs). Here the authors show that mitochondrial MTCH2 regulates mitochondrial fusion and that this fusion is required
Externí odkaz:
https://doaj.org/article/3b42662e2cea47e7be6870e3d559ad27
Autor:
Ayelet Erez, Eytan Ruppin, Igor Ulitsky, Sandesh C.S. Nagamani, Yair Anikster, Raya Eilam, Ben Pode-Shakked, Yehudit Zaltsman-Amir, Keren Bahar Halpern, Erez Persi, Sivan Galai, Noa Stettner, Julia Frug, Alona Sarver, Rom Keshet, Joo Sang Lee, Lital Adler, Shiran Rabinovich, Adi Jacob, Odeya Boukobza Assayag, Omer Goldman, Alon Silberman
Supplementary Figures 1-5 further support our findings regarding the contribution to the maintenance of intracellular pH for ASS1 downregulated cancer cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bf590f6c6dae26b958754b6195138c9
https://doi.org/10.1158/0008-5472.22422482
https://doi.org/10.1158/0008-5472.22422482
Autor:
Ayelet Erez, Eytan Ruppin, Igor Ulitsky, Sandesh C.S. Nagamani, Yair Anikster, Raya Eilam, Ben Pode-Shakked, Yehudit Zaltsman-Amir, Keren Bahar Halpern, Erez Persi, Sivan Galai, Noa Stettner, Julia Frug, Alona Sarver, Rom Keshet, Joo Sang Lee, Lital Adler, Shiran Rabinovich, Adi Jacob, Odeya Boukobza Assayag, Omer Goldman, Alon Silberman
Downregulation of the urea cycle enzyme argininosuccinate synthase (ASS1) by either promoter methylation or by HIF1α is associated with increased metastasis and poor prognosis in multiple cancers. We have previously shown that in normoxic conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a0c71bc872afa3968a802eb42fd39f4
https://doi.org/10.1158/0008-5472.c.6511238.v1
https://doi.org/10.1158/0008-5472.c.6511238.v1
Autor:
Benjamin Sredni, Yona Kalechman, Dan L. Longo, Michael Albeck, Alon Silberman, Elad Noy, Maor H. Pauker, Alain Berrebi, Itai Skornick, Adi Layani-Bazar
PDF file - 766K, Fig. S2: Chemoresistance of myelomonocytic leukemia cells induced by BM Stromal cells is abrogated by AS101.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32578aa034dc7b555d9b3ec6b8972914
https://doi.org/10.1158/0008-5472.22400336
https://doi.org/10.1158/0008-5472.22400336
Autor:
Benjamin Sredni, Yona Kalechman, Dan L. Longo, Michael Albeck, Alon Silberman, Elad Noy, Maor H. Pauker, Alain Berrebi, Itai Skornick, Adi Layani-Bazar
PDF file - 1318K, Fig S4. DTNB or AS101 sensitize high VLA-4 expressing lekemic cells from AML patients, to chemotherapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a1f1086fa643b75c8f4a45f4e78d15b
https://doi.org/10.1158/0008-5472.22400330.v1
https://doi.org/10.1158/0008-5472.22400330.v1
Autor:
Benjamin Sredni, Yona Kalechman, Dan L. Longo, Michael Albeck, Alon Silberman, Elad Noy, Maor H. Pauker, Alain Berrebi, Itai Skornick, Adi Layani-Bazar
PDF file - 129K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5241285e6927d0c444aa93dc9f36706a
https://doi.org/10.1158/0008-5472.22400318.v1
https://doi.org/10.1158/0008-5472.22400318.v1
Autor:
Benjamin Sredni, Yona Kalechman, Dan L. Longo, Michael Albeck, Alon Silberman, Elad Noy, Maor H. Pauker, Alain Berrebi, Itai Skornick, Adi Layani-Bazar
PDF file - 1086K, Fig. S5: Knocking out VLA-4 in mouse myelomonocytic leukemia cells or human AML leukemic cells induces drug sensitivity which is not further enhanced by AS101.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0461c693b69c0a18d52b59abfec84327
https://doi.org/10.1158/0008-5472.22400327.v1
https://doi.org/10.1158/0008-5472.22400327.v1
Autor:
Benjamin Sredni, Yona Kalechman, Dan L. Longo, Michael Albeck, Alon Silberman, Elad Noy, Maor H. Pauker, Alain Berrebi, Itai Skornick, Adi Layani-Bazar
PDF file - 981K, Fig. S6: Inhibition of pAkt mediates AS101's activity involving chemotherapy-induced AML cell death as tested by subG1 accumulation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246da1d8e8a5f6b817697d33028c877b
https://doi.org/10.1158/0008-5472.22400324.v1
https://doi.org/10.1158/0008-5472.22400324.v1
Autor:
Benjamin Sredni, Yona Kalechman, Dan L. Longo, Michael Albeck, Alon Silberman, Elad Noy, Maor H. Pauker, Alain Berrebi, Itai Skornick, Adi Layani-Bazar
Interaction between the integrin VLA-4 on acute myelogenous leukemia (AML) cells with stromal fibronectin is a decisive factor in chemotherapeutic resistance. In this study, we provide a rationale for a drug repositioning strategy to blunt integrin a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d0bb3743cdb83831c5ae03c53331db0
https://doi.org/10.1158/0008-5472.c.6505562
https://doi.org/10.1158/0008-5472.c.6505562
Autor:
Benjamin Sredni, Yona Kalechman, Dan L. Longo, Michael Albeck, Alon Silberman, Elad Noy, Maor H. Pauker, Alain Berrebi, Itai Skornick, Adi Layani-Bazar
PDF file - 1027K, Fig. S1: AS101 induces chemotherapy-induced apoptotic death by decreasing VLA-4 activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203cba1184d7a626118e6ab82fdbcb9d
https://doi.org/10.1158/0008-5472.22400339.v1
https://doi.org/10.1158/0008-5472.22400339.v1