Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Alon Schneider, Hait"'
1
Akademický článek
Deciphering the Role of Host Genetics in Susceptibility to Severe COVID-19
Autor: Madalina Elena Carter-Timofte, Sofie Eg Jørgensen, Mette Ratzer Freytag, Michelle Mølgaard Thomsen, Nanna-Sophie Brinck Andersen, Ali Al-Mousawi, Alon Schneider Hait, Trine H. Mogensen
Publikováno v: Frontiers in Immunology, Vol 11 (2020)
Coronavirus disease-19 (COVID-19) describes a set of symptoms that develop following infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Whilst COVID-19 disease is most serious in patients with significant co-morbidities, t
Externí odkaz: https://doaj.org/article/11aae9949eee4119a697730a8e31c421
Zobrazit plný text záznamu
2
Postpartum Disseminated Herpes Simplex Virus Type 1 Infection With Hemophagocytic Lymphohistiocytosis and Fulminant Neonatal Herpes Infection
Autor: Ali Al-Mousawi, Marie Helleberg, Jakob T Bay, Alon Schneider Hait, David Olagnier, Mette Ratzer Freytag, Sofie E. Jørgensen, Trine H. Mogensen, Michelle M. Thomsen
Publikováno v: Freytag, M R, Jørgensen, S E, Thomsen, M M, Al-Mousawi, A, Hait, A S, Olagnier, D, Bay, J T, Helleberg, M & Mogensen, T H 2022, ' Postpartum Disseminated Herpes Simplex Virus Type 1 Infection With Hemophagocytic Lymphohistiocytosis and Fulminant Neonatal Herpes Infection ', The Journal of Infectious Diseases, vol. 225, no. 1, pp. 157-162 . https://doi.org/10.1093/infdis/jiab290
The present study describes a 19-year-old woman with systemic herpes simplex virus (HSV)-1 infection postpartum, and a fatal course of neonatal herpesvirus infection. The mother experienced an unusual disease course with hemophagocytic lymphohistiocy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8bd0d514c2402a8293f6d2cb8d8480
https://doi.org/10.1093/infdis/jiab290
Zobrazit plný text záznamu
3
SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate
Autor: Christian K. Holm, Anne L. Thielke, Rasmus Ottosen, Thomas B. Poulsen, Jinrong Huang, Alice Knudsen, Lydia Bartsch, Siddharth Balachandran, Marie B. Iversen, Camilla G. Nielsen, Victoria H. Gilchrist, Trine H. Mogensen, Huy-Dung Hoang, Alon Schneider Hait, Sofie E. Jørgensen, Line S. Reinert, Suraj Peri, Jan Rehwinkel, Michael Lappe, Charlotte Möller, Michelle M. Thomsen, John Hiscott, Demi van der Horst, Esben B. Svenningsen, Anne Louise Hansen, Yonglun Luo, Jacob Thyrsted, Manja Idorn, Antonio Alcami, Ensieh Farahani, Julia Blay-Cadanet, Martin R. Jakobsen, Bruno Hernáez, Mirjam Schilling, David Olagnier, Søren R. Paludan, Angela Herengt, Tommy Alain
Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Olagnier, D, Farahani, E, Thyrsted, J, Blay-Cadanet, J, Herengt, A, Idorn, M, Hait, A, Hernaez, B, Knudsen, A, Iversen, M B, Schilling, M, Jørgensen, S E, Thomsen, M, Reinert, L S, Lappe, M, Hoang, H-D, Gilchrist, V H, Hansen, A L, Ottosen, R, Nielsen, C G, Møller, C, van der Horst, D, Peri, S, Balachandran, S, Huang, J, Jakobsen, M, Svenningsen, E B, Poulsen, T B, Bartsch, L, Thielke, A L, Luo, Y, Alain, T, Rehwinkel, J, Alcamí, A, Hiscott, J, Mogensen, T H, Paludan, S R & Holm, C K 2020, ' SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate ', Nature Communications, vol. 11, no. 1, 4938 . https://doi.org/10.1038/s41467-020-18764-3
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Olagnier, D P C, Farahani, E, Jensen, J T, Blay Cadanet, J, Herengt, A A P V, Idorn, M, Schneider Hait, A I, Hernaez, B, Knudsen, A, Iversen, M B, Schilling, M, Jørgensen, S E, Thomsen, M M, Reinert, L S, Lappe, M, Hoang, H D, Gilchrist, V H, Hansen, A L, Ottosen, R, Nielsen, C G, Møller, C, van der Horst, D, Peri, S, Balachandran, S, Huang, J, Jakobsen, M, Svenningsen, E B, Poulsen, T B, Bartsch, L, Thielke, A L, Luo, Y, Alain, T, Rehwinkel, J, Alcamí, A, Hiscott, J, Mogensen, T H, Paludan, S R & Holm, C K 2020, ' SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate ', Nature Communications, vol. 11, 4938 . https://doi.org/10.1038/s41467-020-18764-3
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
Versiones preprint disponibles en: http://hdl.handle.net/10261/216920 y http://hdl.handle.net/10261/217161
Antiviral strategies to inhibit Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) and the pathogenic consequences of COVID-19 ar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c770a0f99e983608245ee2ef5c88b25
https://doaj.org/article/7eb1ed3741cc4fbfa366937b0037cc35
Zobrazit plný text záznamu
4
Essential role of autophagy in restricting poliovirus infection revealed by identification of an ATG7 defect in a poliomyelitis patient
Autor: Trine H. Mogensen, Kristian Alsbjerg Skipper, Martin K. Thomsen, Ensieh Farahani, Sofie E. Jørgensen, Alon Schneider Hait, Jacob Giehm Mikkelsen, Lise Kay, Søren R. Paludan, Mariane H. Schleimann, Johanna Heinz, Michelle M. Thomsen, Yujia Cai, Nanna-Sophie Brinck Andersen, Simon Muller Larsen
Publikováno v: Brinck Andersen, N S, Jørgensen, S E, Skipper, K A, Larsen, S M, Heinz, J, Thomsen, M M, Farahani, E, Cai, Y, Hait, A S, Kay, L, Giehm Mikkelsen, J, Høgsbjerg Schleimann, M, Thomsen, M K, Paludan, S R & Mogensen, T H 2021, ' Essential role of autophagy in restricting poliovirus infection revealed by identification of an ATG7 defect in a poliomyelitis patient ', Autophagy, vol. 17, no. 9, pp. 2449-2464 . https://doi.org/10.1080/15548627.2020.1831800
Autophagy
Paralytic poliomyelitis is a rare disease manifestation following poliovirus (PV) infection. The disease determinants remain largely unknown. We used whole exome sequencing to uncover possible contributions of host genetics to the development of dise
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52af82cd582d877d97ab3fc590191c99
https://pure.au.dk/portal/da/publications/essential-role-of-autophagy-in-restricting-poliovirus-infection-revealed-by-identification-of-an-atg7-defect-in-a-poliomyelitis-patient(a498e2fb-f7a9-4eb3-8c46-a0a229da79ab).html
Zobrazit plný text záznamu
5
Whole-Exome Sequencing of Patients With Recurrent HSV-2 Lymphocytic Mollaret Meningitis
Autor: Mette Christiansen, Maibritt Mardahl, Alon Schneider Hait, Christian Brandt, Simon Muller Larsen, Michelle M. Thomsen, Trine H. Mogensen, Toke S. Barfod, Marie Helleberg
Publikováno v: Hait, A S, Thomsen, M M, Larsen, S M, Helleberg, M, Mardahl, M, Barfod, T S, Christiansen, M, Brandt, C & Mogensen, T H 2021, ' Whole-Exome Sequencing of Patients With Recurrent HSV-2 Lymphocytic Mollaret Meningitis ', The Journal of Infectious Diseases, vol. 223, no. 10, pp. 1776-1786 . https://doi.org/10.1093/infdis/jiaa589
Recurrent lymphocytic meningitis, also referred to as Mollaret meningitis, is a rare neurological disease characterized mainly by reactivation of herpes simplex virus 2 (HSV-2) from sensory ganglia. However, the underlying host immune determinants an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd312c0142897abf404d84833320541f
https://pure.au.dk/portal/da/publications/wholeexome-sequencing-of-patients-with-recurrent-hsv2-lymphocytic-mollaret-meningitis(bf70d9ec-a3f4-450f-aad6-1dd930710482).html
Zobrazit plný text záznamu
6
Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans
Autor: Søren R. Paludan, Alon Schneider Hait, Sathya Darmalinggam, Mette Christiansen, Simon Muller Larsen, Jørgen Kjems, Darshana D. Kadekar, Kristina Eriksson, Serge Mostowy, Liviu Ionut Moldovan, Nanna-Sophie Brinck Andersen, Vanessa Sancho-Shimizu, Trine H. Mogensen, Lasse Sommer Kristensen, Isobel Parkes, David Olagnier, Marie Helleberg, Demi van der Horst, Michelle M. Thomsen, Mette Ratzer Freytag, Kristian Alsbjerg Skipper, Stine H. Rahbek, Jacob Giehm Mikkelsen, Christian Brandt, Chiranjeevi Bodda, Fanghui Ren
Publikováno v: Hait, A S, Olagnier, D, Sancho-Shimizu, V, Skipper, K A, Helleberg, M, Larsen, S M, Bodda, C, Moldovan, L I, Ren, F, Brinck Andersen, N-S, Thomsen, M M, Freytag, M R, Darmalinggam, S, Parkes, I, Kadekar, D D, Rahbek, S H, van der Horst, D, Kristensen, L S, Eriksson, K, Kjems, J, Mostowy, S, Christiansen, M, Mikkelsen, J G, Brandt, C T, Paludan, S R & Mogensen, T H 2020, ' Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans ', Science Immunology, vol. 5, no. 54, eabc2691 . https://doi.org/10.1126/sciimmunol.abc2691
Hait, A S, Olagnier, D, Sancho-Shimizu, V, Skipper, K A, Helleberg, M, Larsen, S M, Bodda, C, Moldovan, L I, Ren, F, Andersen, N S B, Thomsen, M M, Freytag, M R, Darmalinggam, S, Parkes, I, Kadekar, D D, Rahbek, S H, van der Horst, D, Kristensen, L S, Eriksson, K, Kjems, J, Mostowy, S, Christiansen, M, Mikkelsen, J G, Brandt, C T, Paludan, S R & Mogensen, T H 2021, ' Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans ', Science immunology, vol. 5, no. 54, eabc2691 . https://doi.org/10.1126/SCIIMMUNOL.ABC2691
Science Immunology
Recurrent herpesvirus infections can manifest in different forms of disease, including cold sores, genital herpes, and encephalitis. There is an incomplete understanding of the genetic and immunological factors conferring susceptibility to recurrent
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e2d27ad827935f3a3c72318f2fa311
https://pure.au.dk/portal/da/publications/defects-in-lc3b2-and-atg4a-underlie-hsv2-meningitis-and-reveal-a-critical-role-for-autophagy-in-antiviral-defense-in-humans(660e28c6-e88f-4155-8813-69748e66d63d).html
Zobrazit plný text záznamu
9
Author Correction: SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate
Autor: Huy-Dung Hoang, Yonglun Luo, Jacob Thyrsted, Esben B. Svenningsen, Anne Louise Hansen, Sofie E. Jørgensen, Jinrong Huang, Camilla G. Nielsen, Rasmus Ottosen, Christian K. Holm, Alice Knudsen, Antonio Alcami, Marie B. Iversen, Lydia Bartsch, Trine H. Mogensen, Martin R. Jakobsen, Anne L. Thielke, Thomas B. Poulsen, Charlotte Möller, Alon Schneider Hait, Jan Rehwinkel, John Hiscott, Michael Lappe, Michelle M. Thomsen, Manja Idorn, Suraj Peri, Line S. Reinert, Ensieh Farahani, Søren R. Paludan, Angela Herengt, Tommy Alain, Siddharth Balachandran, Bruno Hernáez, Demi van der Horst, Victoria H. Gilchrist, Julia Blay-Cadanet, Mirjam Schilling, David Olagnier
Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Nature Communications
Olagnier, D, Farahani, E, Thyrsted, J, Blay-Cadanet, J, Herengt, A, Idorn, M, Hait, A, Hernaez, B, Knudsen, A, Iversen, M B, Schilling, M, Jørgensen, S E, Thomsen, M, Reinert, L S, Lappe, M, Hoang, H-D, Gilchrist, V H, Hansen, A L, Ottosen, R, Nielsen, C G, Møller, C, van der Horst, D, Peri, S, Balachandran, S, Huang, J, Jakobsen, M, Svenningsen, E B, Poulsen, T B, Bartsch, L, Thielke, A L, Luo, Y, Alain, T, Rehwinkel, J, Alcamí, A, Hiscott, J, Mogensen, T H, Paludan, S R & Holm, C K 2020, ' Author Correction : SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate ', Nature Communications, vol. 11, no. 1, 5419 . https://doi.org/10.1038/s41467-020-19363-y
Antiviral strategies to inhibit Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) and the pathogenic consequences of COVID-19 are urgently required. Here, we demonstrate that the NRF2 antioxidant gene expression pathway is suppressed in bio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4188a7a8fff0f36d3b4eac90957497
https://doaj.org/article/7a767ab0a50943a0a5a6e85eaa10ccfe
Zobrazit plný text záznamu
10
Cutting Edge: Genetic Association between IFI16 Single Nucleotide Polymorphisms and Resistance to Genital Herpes Correlates with IFI16 Expression Levels and HSV-2-Induced IFN-β Expression
Autor: Trine H. Mogensen, Petra Tunbäck, Leonid Padyukov, Alexandra Svensson, Kristina Eriksson, Jan-Åke Liljeqvist, Inger Nordström, Kerstin Schlüter, Søren R. Paludan, Alon Schneider Hait
Publikováno v: Eriksson, K, Svensson, A, Hait, A S, Schlüter, K, Tunbäck, P, Nordström, I, Padyukov, L, Liljeqvist, J-Å, Mogensen, T H & Paludan, S R 2017, ' Cutting Edge : Genetic Association between IFI16 Single Nucleotide Polymorphisms and Resistance to Genital Herpes Correlates with IFI16 Expression Levels and HSV-2-Induced IFN-β Expression ', Journal of Immunology, vol. 199, no. 8, pp. 2613-2617 . https://doi.org/10.4049/jimmunol.1700385
IFN-γ–inducible protein 16 (IFI16) is an immunological DNA sensor proposed to act in the cyclic GMP–AMP synthase–stimulator of IFN genes pathway. Because mice do not have a clear ortholog of IFI16, this system is not suitable for genetic studi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::946aad37b6fc7bd20a4a5dfc96d72eaa
https://pubmed.ncbi.nlm.nih.gov/28893956
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje