Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Alon Oyler-Yaniv"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Controlled cell death can be an efficient anti-viral strategy, but also leads to tissue damage and needs to be balanced. Oyler-Yaniv et al. combine mathematical modelling and microscopy to show that exposure to TNF in response to viral infection caus
Externí odkaz:
https://doaj.org/article/b1d41722ca9e4de692d6e4d06caafe69
Autor:
Alon Oyler-Yaniv, Oleg Krichevsky
Publikováno v:
Bio-Protocol, Vol 8, Iss 7 (2018)
We describe here a method to visualize concentration fields of cytokines around cytokine-secreting cells. The main challenge is that physiological cytokine concentrations can be very low, in the pico-molar range. Since it is currently impossible to m
Externí odkaz:
https://doaj.org/article/39f66c62552c4053b6a79bf328c5fcd7
Autor:
Edoardo Centofanti, Chad Wang, Sandhya Iyer, Oleg Krichevsky, Alon Oyler-Yaniv, Jennifer Oyler-Yaniv
Interferon-γ (IFNγ) is a critical anti-tumor cytokine that has varied effects on different cell types. The global effect of IFNγ in the tumor depends on which cells it acts upon and the spatial extent of its spread. Reported measurements of IFNγ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e13d865b1c2c823cae8bd644283064e2
https://doi.org/10.1101/2023.01.26.525713
https://doi.org/10.1101/2023.01.26.525713
Publikováno v:
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Rapid death of infected cells is an important antiviral strategy. However, fast decisions that are based on limited evidence can be erroneous and cause unnecessary cell death and subsequent tissue damage. How cells optimize their death decision makin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b2096b616e96dc197e537f587c9116
https://escholarship.org/uc/item/6b9166hk
https://escholarship.org/uc/item/6b9166hk
Early commitment to apoptosis is an important antiviral strategy. However, fast decisions that are based on limited evidence can be erroneous and cause unnecessary cell death and tissue damage. How cells optimize their decision making strategy to acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab429e9bdede16c1975fd7456fb3d459
https://doi.org/10.1101/2020.02.20.958942
https://doi.org/10.1101/2020.02.20.958942
Autor:
Grégoire Altan-Bonnet, Joel Kim, Kimon V. Argyropoulos, Kelly Piersanti, Alon Oyler-Yaniv, Carly G. K. Ziegler, Marcel R.M. van den Brink, M. Lia Palomba, Nihal Altan-Bonnet
Publikováno v:
SSRN Electronic Journal.
In cancer biology, functional interpretation of genomic alterations is critical to achieve the promise of genomic profiling in the clinic. For Chronic Lymphocytic Leukemia (CLL), a heterogeneous disease of B-lymphocytes maturing under constitutive B-
Autor:
Farokh Dotiwala, Benjamin M. Whitlock, Lance C. Kam, Claire Hivroz, Audrey Le Floc’h, Judy Lieberman, Roshni Basu, Nicolas Biais, Morgan Huse, Grégory Giannone, Julien Husson, Weiyang Jin, Alon Oyler-Yaniv
Publikováno v:
Cell. 165(1):100-110
The immunological synapse formed between a cytotoxic T lymphocyte (CTL) and an infected or transformed target cell is a physically active structure capable of exerting mechanical force. Here, we investigated whether synaptic forces promote the destru
Publikováno v:
Soft Matter. 11:8939-8947
We present the formalism and experimental implementation of scanning fluorescence correlation spectroscopy (SFCS) for the measurements of soft matter system structure and dynamics. We relate the SFCS function Fourier transform to the system intermedi
Autor:
Mojdeh Shakiba, Sheue-yann Cheng, Nina K. Min, Jennifer Oyler-Yaniv, Alon Oyler-Yaniv, Nihal Altan-Bonnet, Oleg Krichevsky, Grégoire Altan-Bonnet, Ying-Han Chen
Immune cells constantly survey the host for pathogens or tumors and secrete cytokines to alert surrounding cells of these threats. In vivo, activated immune cells secrete cytokines for several hours, yet an acute immune reaction occurs over days. Giv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b386603e0128882174af0aed12a4bd
https://europepmc.org/articles/PMC6611463/
https://europepmc.org/articles/PMC6611463/
Autor:
Carly G. K. Ziegler, Kimon V. Argyropoulos, Alon Oyler-Yaniv, Marcel R.M. van den Brink, Nihal Altan-Bonnet, Joel Kim, M. Lia Palomba, Kelly Piersanti, Grégoire Altan-Bonnet
Publikováno v:
Cell reports
SUMMARY In cancer biology, the functional interpretation of genomic alterations is critical to achieve the promise of genomic profiling in the clinic. For chronic lymphocytic leukemia (CLL), a heterogeneous disease of B-lymphocytes maturing under con