Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alon Diament"'
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 1, p e1005951 (2018)
Ribosome queuing is a fundamental phenomenon suggested to be related to topics such as genome evolution, synthetic biology, gene expression regulation, intracellular biophysics, and more. However, this phenomenon hasn't been quantified yet at a genom
Externí odkaz:
https://doaj.org/article/d12bcf18cefb4475b9766deed626efc8
Autor:
Alon Diament, Tamir Tuller
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 5, p e1004298 (2015)
The study of the 3D architecture of chromosomes has been advancing rapidly in recent years. While a number of methods for 3D reconstruction of genomic models based on Hi-C data were proposed, most of the analyses in the field have been performed on d
Externí odkaz:
https://doaj.org/article/9ea3f7f59b1342018916ca09f3bb1920
Autor:
Zachary Levine, Iris Kalka, Dmitry Kolobkov, Hagai Rossman, Anastasia Godneva, Smadar Shilo, Ayya Keshet, Daphna Weissglas-Volkov, Tal Shor, Alon Diament, Yeela Talmor Barkan, Yaron Aviv, Tom Sharon, Adina Weinberger, Eran Segal, Sneak Peek Administrator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f350fd6375afca843d1d37c8ac12d422
https://doi.org/10.2139/ssrn.4414850
https://doi.org/10.2139/ssrn.4414850
Autor:
Noam Shahar, Meital Avitan, Tamir Tuller, Yael Feldman, Shimshi Atar, Iddo Weiner, Alon Diament, Shira Landman, Iftach Yacoby, Shira Schweitzer
Publikováno v:
Bioinformatics. 35:3365-3371
Motivation Regulation of the amount of protein that is synthesized from genes has proved to be a serious challenge in terms of analysis and prediction, and in terms of engineering and optimization, due to the large diversity in expression machinery a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee06c7d3d09cee6bef9126f7168789ad
https://doi.org/10.1093/bioinformatics/btz080
https://doi.org/10.1093/bioinformatics/btz080
Publikováno v:
Bioinformatics
Motivation The COP9 signalosome is a highly conserved multi-protein complex consisting of eight subunits, which influences key developmental pathways through its regulation of protein stability and transcription. In Arabidopsis thaliana, mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a304d418fd8a26ccdf32e028d911e7c5
https://doi.org/10.1093/bioinformatics/bty1053
https://doi.org/10.1093/bioinformatics/bty1053
Autor:
Larissa Fine, Alon Diament, Dana Yacobi, Boaz Apt, Rachel Cohen-Kupiec, Shir Bahiri Elitzur, Tamir Tuller
Publikováno v:
RNA Biol
The well-established Shine-Dalgarno model suggests that translation initiation in bacteria is regulated via base-pairing between ribosomal RNA (rRNA) and mRNA. However, little is currently known about the contribution of such interactions to the rest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fbd23ba77b345168c706e209b4172f4
https://doi.org/10.1101/2020.07.24.220731
https://doi.org/10.1101/2020.07.24.220731
Publikováno v:
Bioinformatics (Oxford, England).
Motivation MicroRNAs (miRNAs) are short (∼24nt), non-coding RNAs, which downregulate gene expression in many species and physiological processes. Many details regarding the mechanism which governs miRNA-mediated repression continue to elude researc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc24e0e1bd02a7e1960163dff443f2f1
https://pubmed.ncbi.nlm.nih.gov/33320173
https://pubmed.ncbi.nlm.nih.gov/33320173
Autor:
Tamir Tuller, Alon Diament
Publikováno v:
Nucleic Acids Research
It has recently been shown that the organization of genes in eukaryotic genomes, and specifically in 3D, is strongly related to gene expression and function and partially conserved between organisms. However, previous studies of 3D genomic organizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d607954383cd007416574725a8f211
http://europepmc.org/articles/PMC5416853
http://europepmc.org/articles/PMC5416853
Publikováno v:
DNA Research
DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes
DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes
Deciphering the way gene expression regulatory aspects are encoded in viral genomes is a challenging mission with ramifications related to all biomedical disciplines. Here, we aimed to understand how the evolution shapes the bacteriophage lambda gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::941ab65e60d32edc43f99fa9d24dfeda
https://doi.org/10.1093/dnares/dsx005
https://doi.org/10.1093/dnares/dsx005
Autor:
Tamir Tuller, Alon Diament
Publikováno v:
Seminars in celldevelopmental biology. 90
The regulation of gene expression is mediated via the complex three-dimensional (3D) conformation of the genetic material and its interactions with various intracellular factors. Various experimental and computational approaches have been developed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1788ef037fcfae61147bbc09fe4eaeb4
https://pubmed.ncbi.nlm.nih.gov/30030143
https://pubmed.ncbi.nlm.nih.gov/30030143