Výsledky vyhledávání - "Alok, Krishen"

Estimation of risk of neuropsychiatric adverse events from varenicline, bupropion and nicotine patch versus placebo: secondary analysis of results from the EAGLES trial using Bayes factors

Autor: Emma Beard, Sarah E Jackson, Alok Krishen, A. Eden Evins, Robert West, Robert M. Anthenelli, David Lawrence, Thomas McRae, Neal L. Benowitz, Cristina Russ, Lisa St Aubin

Publikováno v: Addiction (Abingdon, England)
Addiction (Abingdon, England), vol 116, iss 10

Author(s): Beard, Emma; Jackson, Sarah E; Anthenelli, Robert M; Benowitz, Neal L; Aubin, Lisa St; McRae, Thomas; Lawrence, David; Russ, Cristina; Krishen, Alok; Evins, A Eden; West, Robert | Abstract: Background and aimsAnalysed using classical frequ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a209850935d939f2cc9d7ed963dd3c4
https://doi.org/10.1111/add.15440

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Cardiovascular adverse events in the drug-development program of bupropion for smoking cessation: A systematic retrospective adjudication effort

Autor: Matthew T. Roe, Jessie Kittle, Alok Krishen, Mingyan Huang, Marsha L. Marquess, Renato D. Lopes, Darren K. McGuire, Vic Hasselblad, Stuart D. Russell, John A. Ascher, Kenneth W. Mahaffey, Matthew Wilson, Brad J. Kolls

Publikováno v: Clinical Cardiology. 40:899-906

Background In 2011, the US Food and Drug Administration requested that GlaxoSmithKline perform retrospective adjudication of cardiovascular (CV) events reported in the bupropion drug-development trials for smoking cessation. Hypothesis Retrospective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6cfdb736a1ea85bd88f0369cb2ac109b
https://doi.org/10.1002/clc.22744

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Safety and efficacy of first-line smoking cessation pharmacotherapies in bipolar disorders: Subgroup analysis of a randomized clinical trial

Autor: Cristina Russ, Alok Krishen, Catherine R. Ayers, A. Eden Evins, Thomas McRae, Jaimee L. Heffner, David Lawrence, Lisa St Aubin, Robert M. Anthenelli, Robert West

Publikováno v: J Affect Disord

ObjectivesPost hoc analyses of EAGLES data to examine safety and efficacy of first-line smoking cessation pharmacotherapies in smokers with bipolar disorders (BD).MethodsSmokers with BD I/II (n = 285; 81.4% with BD I) and a comparison nonpsychiatric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d552f5a3676bc1d1833d11468628c79
https://europepmc.org/articles/PMC8936081/

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Predictors of Neuropsychiatric Adverse Events with Smoking Cessation Medications in the Randomized Controlled EAGLES Trial

Autor: Neal L. Benowitz, Michael Gaffney, Thomas McRae, Robert West, Alok Krishen, A. Eden Evins, David Lawrence, Cristina Russ, Robert M. Anthenelli, Lisa St Aubin

Publikováno v: Journal of general internal medicine, vol 34, iss 6
J Gen Intern Med

BACKGROUND: Pre-treatment factors that increase smokers’ risk of experiencing neuropsychiatric adverse events (NPSAEs) when quitting smoking are unknown. OBJECTIVE: To identify baseline smoker characteristics beyond the history of mental illness th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ad423f57a98fab13d13708375d706e
https://escholarship.org/uc/item/7g8426c4

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Neuropsychiatric Safety and Efficacy of Varenicline, Bupropion, and Nicotine Patch in Smokers With Psychotic, Anxiety, and Mood Disorders in the EAGLES Trial

Autor: Thomas McRae, Alok Krishen, Robert M. Anthenelli, Neal L. Benowitz, Robert West, Melissa Culhane Maravic, Lisa St Aubin, David Lawrence, A. Eden Evins, Cristina Russ

Publikováno v: Evins, A Eden; Benowitz, Neal L; West, Robert; Russ, Cristina; McRae, Thomas; Lawrence, David; et al.(2019). Neuropsychiatric Safety and Efficacy of Varenicline, Bupropion, and Nicotine Patch in Smokers With Psychotic, Anxiety, and Mood Disorders in the EAGLES Trial.. Journal of clinical psychopharmacology, 39(2), 108-116. doi: 10.1097/jcp.0000000000001015. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/3br1c3tx

Author(s): Evins, A Eden; Benowitz, Neal L; West, Robert; Russ, Cristina; McRae, Thomas; Lawrence, David; Krishen, Alok; St Aubin, Lisa; Maravic, Melissa Culhane; Anthenelli, Robert M | Abstract: BACKGROUND:Neuropsychiatric safety and relative effica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e944bbb58912de5d812b22b93896e69a
http://www.escholarship.org/uc/item/3br1c3tx

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A Randomized, Placebo-controlled Trial of the Analgesic Efficacy and Safety of the p38 MAP Kinase Inhibitor, Losmapimod, in Patients With Neuropathic Pain From Lumbosacral Radiculopathy

Autor: Madeline Kelly, Joanne Green, Robert Lai, Jonathan Bullman, Thor Ostenfeld, Praveen Anand, Alok Krishen, Joachim Scholz

Publikováno v: The Clinical Journal of Pain. 31:283-293

Preclinical studies have demonstrated involvement of p38 mitogen-activated protein kinase signaling pathways in the development of persistent pain after peripheral nerve injury. A double-blind, randomized, placebo-controlled study was undertaken to e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bf56b2e451568b0ce44d7b98b4f752a
https://doi.org/10.1097/ajp.0000000000000122

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Factors associated with the efficacy of smoking cessation treatments and predictors of smoking abstinence in EAGLES

Autor: Robert, West, A Eden, Evins, Neal L, Benowitz, Cristina, Russ, Thomas, McRae, David, Lawrence, Lisa, St Aubin, Alok, Krishen, Melissa C, Maravic, Robert M, Anthenelli

Publikováno v: Addiction (Abingdon, England)

Aims To assess (1) how far the efficacies of front‐line smoking cessation pharmacotherapies vary as a function of smoker characteristics and (2) associations between these characteristics and success of smoking cessation attempts. Design Prospectiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b558002fe3583a793ccd244698f6f553
https://pubmed.ncbi.nlm.nih.gov/29508470

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Cardiovascular adverse events in the drug-development program of bupropion for smoking cessation: A systematic retrospective adjudication effort

Autor: Jessie, Kittle, Renato D, Lopes, Mingyan, Huang, Marsha L, Marquess, Matthew D, Wilson, John, Ascher, Alok, Krishen, Vic, Hasselblad, Brad J, Kolls, Matthew T, Roe, Darren K, McGuire, Stuart D, Russell, Kenneth W, Mahaffey

Publikováno v: Clinical cardiology. 40(10)

BACKGROUND: In 2011, the US Food and Drug Administration requested that GlaxoSmithKline perform retrospective adjudication of cardiovascular (CV) events reported in the bupropion drug‐development trials for smoking cessation. HYPOTHESIS: Retrospect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2f11c9e950ec25039f7006094d580d4b
https://pubmed.ncbi.nlm.nih.gov/28605035

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Relief of Menstrual Symptoms and Migraine with a Single-Tablet Formulation of Sumatriptan and Naproxen Sodium

Autor: Susan A. McDonald, Michael P. Diamond, Jeanne E. Ballard, Vincent T. Martin, Shelly E. Lener, Alok Krishen, Frederick J. Derosier, Lisa K. Mannix

Publikováno v: Journal of Women's Health. 23:389-396

Dysmenorrhea and menstrual migraine may share a common pathogenic pathway. Both appear to be mediated, in part, by an excess of prostaglandin production that occurs during menstruation.Data were pooled from two replicate randomized controlled trials

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcaac34808090a36f1ef5ab347a6fa33
https://doi.org/10.1089/jwh.2013.4577

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Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial

Autor: David Lawrence, Thomas McRae, Cristina Russ, A. Eden Evins, Robert West, Alok Krishen, John A. Ascher, Lisa St Aubin, Neal L. Benowitz, Robert M. Anthenelli

Publikováno v: Lancet (London, England), vol 387, iss 10037

Summary Background Substantial concerns have been raised about the neuropsychiatric safety of the smoking cessation medications varenicline and bupropion. Their efficacy relative to nicotine patch largely relies on indirect comparisons, and there is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aef3f9d0e5c1cccf466f2e60e95078f
https://escholarship.org/uc/item/7278r2jj

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