IRF5 promotes the proliferation of human thyroid cancer cells

Autor: Massimino Michele, Vigneri Paolo, Fallica Manuela, Fidilio Annamaria, Aloisi Alessandra, Frasca Francesco, Manzella Livia

Publikováno v: Molecular Cancer, Vol 11, Iss 1, p 21 (2012)

Abstract Background Interferon Regulatory Factor 5 is a transcription factor that regulates the expression of genes involved in the response to viral infection and in the stimulation of the immune system. Moreover, multiple studies have demonstrated

Externí odkaz: https://doaj.org/article/c15dde6562aa4257b492a17b1f7fc45e

Proteomic expression profile of injured rat peripheral nerves revealed biological networks and processes associated with nerve regeneration

Autor: Alessandro Sannino, Stefania De Domenico, Michel Salzet, Isabelle Fournier, Anna Maria Giudetti, Velia La Pesa, Alessandro Romano, Ilaria Cicalini, Eleonora Stanca, Daniele Vergara, Angelo Quattrini, Damiana Pieragostino, Federica Cerri, Elisa Storelli, Laura Aloisi, Michele Maffia, Julien Franck

Publikováno v: Journal of Cellular Physiology
Journal of Cellular Physiology, Wiley, 2018, 233 (8), pp.6207-6223. ⟨10.1002/jcp.26478⟩
Journal of Cellular Physiology, 2018, 233 (8), pp.6207-6223. ⟨10.1002/jcp.26478⟩

International audience; Peripheral nerve regeneration is regulated through the coordinated spatio-temporal activation of multiple cellular pathways. In this work, an integrated proteomics and bioinformatics approach was employed to identify different

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0794d2f97c2e7bd5a540f1e9adf217
https://www.hal.inserm.fr/inserm-02940755

Trop-2, Na ⁺ /K ⁺ ATPase, CD9, PKCα, cofilin assemble a membrane signaling super-complex that drives colorectal cancer growth and invasion.

Autor: Guerra E; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), University 'G. D'Annunzio', Chieti, Italy.; Department of Medical, Oral and Biotechnological Sciences, University 'G. D'Annunzio', Chieti, Italy., Relli V; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), University 'G. D'Annunzio', Chieti, Italy., Ceci M; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), University 'G. D'Annunzio', Chieti, Italy., Tripaldi R; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), University 'G. D'Annunzio', Chieti, Italy., Simeone P; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), University 'G. D'Annunzio', Chieti, Italy.; Department of Medicine and Aging Sciences, University 'G. D'Annunzio', Chieti, Italy.; Laboratory of Cytomorphology, Center for Advanced Studies and Technology (CAST), University 'G. D'Annunzio', Chieti, Italy., Aloisi AL; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), University 'G. D'Annunzio', Chieti, Italy., Pantalone L; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), University 'G. D'Annunzio', Chieti, Italy., La Sorda R; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), University 'G. D'Annunzio', Chieti, Italy., Lattanzio R; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), University 'G. D'Annunzio', Chieti, Italy.; Department of Innovative Technologies in Medicine & Dentistry, University 'G.D'Annunzio', Chieti, Italy., Sacchetti A; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), University 'G. D'Annunzio', Chieti, Italy.; Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands., Havas K; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), University 'G. D'Annunzio', Chieti, Italy.; FIRC Institute of Molecular Oncology (IFOM), Milan, Italy., Guarnieri S; Laboratory of Cell Physiology, Center for Advanced Studies and Technology (CAST), University 'G. D'Annunzio', Chieti, Italy.; Department of Neuroscience, Imaging and Clinical Sciences, University 'G. D'Annunzio', Chieti, Italy., Vergara D; Department of Biological and Environmental Sciences and Technologies, University of Salento, Lecce, Italy., Fournier I; Inserm U-1192, Laboratoire de Protéomique, Réponse Inflammatoire, Spectrométrie de Masse, Université de Lille 1, Cité Scientifique, Villeneuve D'Ascq Cedex, France., Salzet M; Inserm U-1192, Laboratoire de Protéomique, Réponse Inflammatoire, Spectrométrie de Masse, Université de Lille 1, Cité Scientifique, Villeneuve D'Ascq Cedex, France., Tinari N; Department of Medical, Oral and Biotechnological Sciences, University 'G. D'Annunzio', Chieti, Italy., Piantelli M; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), University 'G. D'Annunzio', Chieti, Italy.; Department of Medical, Oral and Biotechnological Sciences, University 'G. D'Annunzio', Chieti, Italy., Trerotola M; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), University 'G. D'Annunzio', Chieti, Italy. marco.trerotola@unich.it.; Department of Medical, Oral and Biotechnological Sciences, University 'G. D'Annunzio', Chieti, Italy. marco.trerotola@unich.it., Alberti S; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), University 'G. D'Annunzio', Chieti, Italy. salberti@unime.it.; Unit of Medical Genetics, Department of Biomedical Sciences, University of Messina, Messina, Italy. salberti@unime.it.

Publikováno v: Oncogene [Oncogene] 2022 Mar; Vol. 41 (12), pp. 1795-1808. Date of Electronic Publication: 2022 Feb 07.

Trop-2 Induces Tumor Growth Through AKT and Determines Sensitivity to AKT Inhibitors.

Autor: Guerra E; Unit of Cancer Pathology, CeSI-MeT, University 'G. d'Annunzio,' Chieti, Italy., Trerotola M; Unit of Cancer Pathology, CeSI-MeT, University 'G. d'Annunzio,' Chieti, Italy., Tripaldi R; Unit of Cancer Pathology, CeSI-MeT, University 'G. d'Annunzio,' Chieti, Italy., Aloisi AL; Unit of Cancer Pathology, CeSI-MeT, University 'G. d'Annunzio,' Chieti, Italy., Simeone P; Unit of Cancer Pathology, CeSI-MeT, University 'G. d'Annunzio,' Chieti, Italy., Sacchetti A; Unit of Cancer Pathology, CeSI-MeT, University 'G. d'Annunzio,' Chieti, Italy., Relli V; Unit of Cancer Pathology, CeSI-MeT, University 'G. d'Annunzio,' Chieti, Italy., D'Amore A; Unit of Cancer Pathology, CeSI-MeT, University 'G. d'Annunzio,' Chieti, Italy., La Sorda R; Unit of Cancer Pathology, CeSI-MeT, University 'G. d'Annunzio,' Chieti, Italy., Lattanzio R; Unit of Cancer Pathology, CeSI-MeT, University 'G. d'Annunzio,' Chieti, Italy. Department of Medical, Oral and Biotechnological Sciences, University 'G. d'Annunzio,' Chieti, Italy., Piantelli M; Unit of Cancer Pathology, CeSI-MeT, University 'G. d'Annunzio,' Chieti, Italy. Department of Medical, Oral and Biotechnological Sciences, University 'G. d'Annunzio,' Chieti, Italy., Alberti S; Unit of Cancer Pathology, CeSI-MeT, University 'G. d'Annunzio,' Chieti, Italy. Department of Neuroscience, Imaging and Clinical Sciences, Unit of Physiology and Physiopathology, University 'G. d'Annunzio,' Chieti, Italy. s.alberti@unich.it.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2016 Aug 15; Vol. 22 (16), pp. 4197-205. Date of Electronic Publication: 2016 Mar 28.

The Trop-2 signalling network in cancer growth.

Autor: Guerra E; Unit of Cancer Pathology, Department of Oncology and Experimental Medicine and CeSI, Foundation University 'G. d'Annunzio', Chieti, Italy., Trerotola M, Aloisi AL, Tripaldi R, Vacca G, La Sorda R, Lattanzio R, Piantelli M, Alberti S

Publikováno v: Oncogene [Oncogene] 2013 Mar 21; Vol. 32 (12), pp. 1594-600. Date of Electronic Publication: 2012 May 07.