Identification of markers for the selection of patients undergoing renal cell carcinoma-specific immunotherapy

Autor: Sebastian W. Melchior, Alois Harder, Friedrich Lottspeich, Rudolf Lichtenfels, Thomas M. Halder, Matthias Menig, Jürgen Bukur, Angelika Ackermann, Michael Kersten, Walburgis Brenner, Roland Kellner, Bernd Muehlenweg, Derek Atkins, Joachim Beck, Barbara Seliger

Publikováno v: PROTEOMICS. 3:979-990

Renal cell carcinoma (RCC) represents the most common malignant tumor in the kidney and is resistant to conventional therapies. The diagnosis of RCC is often delayed leading to progression and metastatic spread of the disease. Thus, validated markers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b56f74c727abbe0a85fdd0a6236e5b
https://doi.org/10.1002/pmic.200300404

Proteomic analysis of Brucella suis under oxygen deficiency reveals flexibility in adaptive expression of various pathways

Autor: Michael Kersten, Alois Harder, Séverine Loisel-Meyer, Holger C. Scholz, Sascha Al Dahouk, Stephan Köhler, Véronique Jubier-Maurin, Herbert Tomaso, Heinrich Neubauer

Publikováno v: Proteomics
Proteomics, Wiley-VCH Verlag, 2009, 9 (11), pp.3011-21. ⟨10.1002/pmic.200800266⟩

International audience; Low oxygen tension was proposed to be one of the environmental parameters characteristic of the patho-physiological conditions of natural infections by Brucella suis. We previously showed that various respiratory pathways may

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49a4109b21edeb0ea12a43aff2f0720f
https://hal.archives-ouvertes.fr/hal-00420519

Sample Preparation Procedure for Cellular Fungi

Autor: Alois Harder

Publikováno v: Methods in Molecular Biology™ ISBN: 9781603272094

A crucial step in quantitative proteomics is an artefact free and reproducible sample preparation protocol, which has to be adapted and optimized to nearly all types of cells. Here we provide a sample preparation method for quantitative proteomics of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::826020a2e2aebdb7b28311c09a8b1f90
https://doi.org/10.1007/978-1-60327-210-0_21

First identification and functional characterization of an immunogenic protein in unculturable haemotrophic Mycoplasmas (Mycoplasma suis HspA1)

Autor: Mathias Ritzmann, Max M. Wittenbrink, Katharina Hoelzle, Heinz-Adolf Schoon, Alois Harder, Heike Aupperle, Karl Heinritzi, Ludwig E. Hoelzle

The antigenic structures of the haemotrophic Mycoplasma suis, an epicellular parasite of porcine erythrocytes, are largely unknown due to its unculturability. In this study, serological proteome and mass spectrometry analyses allowed the characteriza

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f934b6150ac00186c04cc6c88fdece24

Comparison of yeast cell protein solubilization procedures for two-dimensional electrophoresis

Autor: Robert Wildgruber, Alois Harder, Arek Nawrocki, Angelika Görg, Peter Mose Larsen, Stephen J. Fey

Publikováno v: Harder, A, Wildgruber, R, Nawrocki, A, Fey, S J, Larsen, P M & Görg, A 1999, ' Comparison of Yeast Cell Protein Solubilization Procedures for Two-dimensional Electrophoresis ', Electrophoresis, vol. 20, no. 4-5, pp. 826-9 . https://doi.org/10.1002/(SICI)1522-2683(19990101)20:4/5<826::AID-ELPS826>3.0.CO;2-A
From Genome to Proteome: Advances in the Practice and Application of Proteomics

Udgivelsesdato: null-null Three different procedures for the solubilization of yeast (S. cerevisiae) cell proteins were compared on the basis of the obtained two-dimensional (2-D) polypeptide patterns. Major emphasis was laid on minimizing handling s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681fd3d2141aa55f38871709adeb20ad
https://pubmed.ncbi.nlm.nih.gov/10344254