Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Almuth F, Kessler"'
Autor:
Mirjam Renovanz, Melina Hippler, Martin Voss, Jens Wehinger, Almuth F. Keßler, Jens Gempt, Minou Nadji-Ohl, Carolin Weiß Lucas, Marion Rapp, Martin Misch, Jan Coburger, Marcus Mehlitz, Jürgen Meixensberger, Naureen Keric, Ghazaleh Tabatabai, Maria Blettner, Melanie Schranz, Susanne Singer
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background Patients with high-grade gliomas (HGG) often suffer from high distress and require psychosocial support. However, due to neurological and neurocognitive deficits, adequate assessment of distress and support needs remains challengi
Externí odkaz:
https://doaj.org/article/b4d59cd38c304cdda9ec43e3eaac9abd
Autor:
Ellaine Salvador, Theresa Köppl, Julia Hörmann, Sebastian Schönhärl, Polina Bugaeva, Almuth F. Kessler, Malgorzata Burek, Ralf-Ingo Ernestus, Mario Löhr, Carsten Hagemann
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 185 (2023)
In a recent study, we showed in an in vitro murine cerebellar microvascular endothelial cell (cerebEND) model as well as in vivo in rats that Tumor-Treating Fields (TTFields) reversibly open the blood–brain barrier (BBB). This process is facilitate
Externí odkaz:
https://doaj.org/article/a19fe7c08e3444deaf7e275c1636f92f
Publikováno v:
Frontiers in Surgery, Vol 8 (2021)
Background: Removal of anteriorly located tumors of the upper cervical spine and craniovertebral junction (CVJ) is a particular surgical challenge. Extensive approaches are associated with pain, restricted mobility of neck and head and, in case of fo
Externí odkaz:
https://doaj.org/article/859df402dc3647bfbb42bb01835285f8
Autor:
Thomas Linsenmann, Camelia M. Monoranu, Balint Alkonyi, Thomas Westermaier, Carsten Hagemann, Almuth F. Kessler, Ralf-Ingo Ernestus, Mario Löhr
Publikováno v:
Interdisciplinary Neurosurgery, Vol 16, Iss , Pp 7-11 (2019)
Background: Cerebellar liponeurocytoma is an extremely rare tumour entity of the central nervous system. It is histologically characterised by prominent neuronal/neurocytic differentiation with focal lipidisation and corresponding histologically to W
Externí odkaz:
https://doaj.org/article/b8aec5d36b954167b0ef99618dd509de
Autor:
Mario Löhr, Almuth F. Kessler, Camelia-Maria Monoranu, Jens Grosche, Thomas Linsenmann, Ralf-Ingo Ernestus, Wolfgang Härtig
Publikováno v:
BMC Neurology, Vol 19, Iss 1, Pp 1-5 (2019)
Abstract Background Scattered extracellular deposits of amyloid within the brain parenchyma can be found in a heterogeneous group of diseases. Its condensed accumulation in the white matter without evidence for systemic amyloidosis is known as primar
Externí odkaz:
https://doaj.org/article/a2210cf4cba0425cb1276b7ce0ec9d4a
Autor:
Ellaine Salvador, Almuth F. Kessler, Dominik Domröse, Julia Hörmann, Clara Schaeffer, Aiste Giniunaite, Malgorzata Burek, Catherine Tempel-Brami, Tali Voloshin, Alexandra Volodin, Adel Zeidan, Moshe Giladi, Ralf-Ingo Ernestus, Mario Löhr, Carola Y. Förster, Carsten Hagemann
Publikováno v:
Biomolecules, Vol 12, Iss 10, p 1348 (2022)
Despite the availability of numerous therapeutic substances that could potentially target CNS disorders, an inability of these agents to cross the restrictive blood–brain barrier (BBB) limits their clinical utility. Novel strategies to overcome the
Externí odkaz:
https://doaj.org/article/b91b48214a2d4b4198e80fa053ef9dd0
Autor:
Maria Breun, Camelia M. Monoranu, Almuth F. Kessler, Cordula Matthies, Mario Löhr, Carsten Hagemann, Andreas Schirbel, Steven P. Rowe, Martin G. Pomper, Andreas K. Buck, Hans-Jürgen Wester, Ralf-Ingo Ernestus, Constantin Lapa
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
We have recently demonstrated CXCR4 overexpression in vestibular schwannomas (VS). This study investigated the feasibility of CXCR4-directed positron emission tomography/computed tomography (PET/CT) imaging of VS using the radiolabeled chemokine liga
Externí odkaz:
https://doaj.org/article/bf22db3301794e1282b9becb467c713c
Autor:
Hagemann, Jonas Feldheim, Almuth F. Kessler, Julia J. Feldheim, Dominik Schmitt, Christoph Oster, Lazaros Lazaridis, Martin Glas, Ralf-Ingo Ernestus, Camelia M. Monoranu, Mario Löhr, Carsten
Publikováno v:
Cancers; Volume 15; Issue 11; Pages: 2907
The metastatic suppressor BRMS1 interacts with critical steps of the metastatic cascade in many cancer entities. As gliomas rarely metastasize, BRMS1 has mainly been neglected in glioma research. However, its interaction partners, such as NFκB, VEGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::ea271d2427f0f05b8062c1ee9bec4af6
Autor:
Christel C. Herold-Mende, Matthias Simon, Andreas Unterberg, Andreas von Deimling, Juergen Debus, Amir Abdollahi, Manfred Westphal, Christian Senft, Steffi Urbschat, Ralf Ketter, Mario Loehr, Niels Grabe, Almuth F. Kessler, Konstaninos Gousias, Katrin Lamszus, Klaus Zweckberger, Gerhard Jungwirth, Melissa Schmidt, Felix Sahm, Andreas Mock, Saskia Roesch, Christine Jungk, Rolf Warta, Anna Theresa Ull, Fang Liu, Steffen Dettling, Carmen Rapp
Fig. S1: Workflow; Fig. S2: Representative gating strategy for TissueFAXS analysis; Fig. S3: Analysis of helper, cytotoxic and regulatory T cell infiltration and the proportion of PD-1-expressing T cells; Fig. S4: Association between the infiltration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e656ac20209e62f6340973ea9508fa
https://doi.org/10.1158/1078-0432.22470666
https://doi.org/10.1158/1078-0432.22470666
Autor:
Christel C. Herold-Mende, Matthias Simon, Andreas Unterberg, Andreas von Deimling, Juergen Debus, Amir Abdollahi, Manfred Westphal, Christian Senft, Steffi Urbschat, Ralf Ketter, Mario Loehr, Niels Grabe, Almuth F. Kessler, Konstaninos Gousias, Katrin Lamszus, Klaus Zweckberger, Gerhard Jungwirth, Melissa Schmidt, Felix Sahm, Andreas Mock, Saskia Roesch, Christine Jungk, Rolf Warta, Anna Theresa Ull, Fang Liu, Steffen Dettling, Carmen Rapp
Purpose:Clinically aggressive meningiomas (MGMs) are rare but treatment-resistant tumors in need for more effective therapies. Because tumor-infiltrating T lymphocytes (TILs) are essential for successful immunotherapy, we assessed TIL numbers and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e45d2edc74924eae29a13f43864624
https://doi.org/10.1158/1078-0432.c.6527649.v1
https://doi.org/10.1158/1078-0432.c.6527649.v1