Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Almut Dufner"'
Autor:
Caterina Curato, Biana Bernshtein, Eva Zupancič, Almut Dufner, Diego Jaitin, Amir Giladi, Eyal David, Louise Chappell-Maor, Dena Leshkowitz, Klaus-Peter Knobeloch, Ido Amit, Helena F. Florindo, Steffen Jung
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Dendritic cells (DC) are unrivaled in their potential to prime naive T cells by presenting antigen and providing costimulation. DC are furthermore believed to decode antigen context by virtue of pattern recognition receptors and to polarize T cells t
Externí odkaz:
https://doaj.org/article/505d7b8f1a8545449ac06c8297fca0f3
Autor:
Klaus-Peter Knobeloch, Almut Dufner
Publikováno v:
Biochemical Society Transactions
Protein modification by ubiquitin is one of the most versatile posttranslational regulations and counteracted by almost 100 deubiquitinating enzymes (DUBs). USP8 was originally identified as a growth regulated ubiquitin-specific protease and is like
Autor:
Eyal David, Almut Dufner, Biana Bernshtein, Louise Chappell-Maor, Ido Amit, Caterina Curato, Klaus-Peter Knobeloch, Dena Leshkowitz, Steffen Jung, Amir Giladi, Eva Zupancic, Diego Jaitin, Helena F. Florindo
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
Frontiers in Immunology
Dendritic cells (DC) are unrivaled in their potential to prime naive T cells by presenting antigen and providing costimulation. DC are furthermore believed to decode antigen context by virtue of pattern recognition receptors and to polarize T cells t
Autor:
Almut Dufner, Klaus-Peter Knobeloch
Protein modification by ubiquitin plays a critical role in multiple cellular processes and is counteracted by the activity of ∼90 deubiquitinating enzymes (DUBs) encoded by the human genome. Beside...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b58345386b775c7df99db21fbedba2
https://europepmc.org/articles/PMC4825788/
https://europepmc.org/articles/PMC4825788/
Autor:
Thorsten Kurz, Andreas Schlosser, Marcus Groettrup, Thorsten Buch, Ari Waisman, Sandra Niendorf, Wolfgang W. A. Schamel, Anja Basters, Annette Aichem, Deborah Yablonski, Anne Schönle, Almut Dufner, Marco Prinz, Klaus-Peter Knobeloch, Agnes Kisser, Sonja Reissig
The modification of proteins by ubiquitin has a major role in cells of the immune system and is counteracted by various deubiquitinating enzymes (DUBs) with poorly defined functions. Here we identified the ubiquitin-specific protease USP8 as a regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb30f7a87eceff8380cd706f27ed121
https://www.zora.uzh.ch/id/eprint/123052/
https://www.zora.uzh.ch/id/eprint/123052/
Autor:
Brian A. Hemmings, George Thomas, Boudewijn M.T. Burgering, Almut Dufner, Mirjana Andjelkovic
Publikováno v:
Molecular and Cellular Biology. 19:4525-4534
Mitogens induce the coordinated activation of a number of anabolic events which culminate in cell growth and division (41). Recent studies have defined the distinction between growth and proliferation, demonstrating the dominance of growth in this pr
Autor:
Tak W. Mak, Almut Dufner, Alisha R. Elford, Håkan Hall, Pamela S. Ohashi, Gordon S. Duncan, Andrew Wakeham
Publikováno v:
Molecular and cellular biology. 28(5)
We have previously reported the cloning and characterization of CARD6, a caspase recruitment domain (CARD)-containing protein that is structurally related to the interferon (IFN)-inducible GTPases. CARD6 associates with microtubules and with receptor
Autor:
Almut Dufner, Tak W. Mak
Publikováno v:
Cell cycle (Georgetown, Tex.). 5(8)
In recent years, a number of proteins have been identified that contain a homotypic interaction motif called the caspase recruitment domain (CARD). Most proteins containing a CARD are involved in pathways regulating apoptosis or adaptive or innate im
Proteins containing a caspase recruitment domain (CARD) play pivotal roles in signal transduction leading to apoptosis and NF-κB activation and inflammation. Here we identify and characterize human and mouse CARD protein 6 (CARD6), CARD-containing p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5808fb208749ffcdff6c52864169eec
https://europepmc.org/articles/PMC1327733/
https://europepmc.org/articles/PMC1327733/
Autor:
Almut Dufner, George Thomas
Publikováno v:
Experimental cell research. 253(1)
The highly homologous 40S ribosomal protein S6 kinases (S6K1 and S6K2) play a key role in the regulation of cell growth by controlling the biosynthesis of translational components which make up the protein synthetic apparatus, most notably ribosomal