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The conotoxin Contulakin-G reverses hypersensitivity observed in rodent models of cancer-induced bone pain without inducing tolerance or motor disturbance.

Autor: Martin LF; Departments of Pharmacology.; Anesthesiology, and.; Comprehensive Center for Pain and Addiction, College of Medicine, The University of Arizona, Tucson, AZ, United States., Almuslim M; Departments of Pharmacology.; Department of Pharmacology, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia., Ismail KA; Anesthesiology, and., Ibrahim MM; Departments of Pharmacology.; Anesthesiology, and.; Comprehensive Center for Pain and Addiction, College of Medicine, The University of Arizona, Tucson, AZ, United States., Moutal A; Department of Pharmacology and Physiology, School of Medicine, Saint Louis University, St. Louis, MO, United States., Cheng K; Departments of Pharmacology., Stratton HJ; Departments of Pharmacology., Price TJ; Department of Neuroscience and Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX, United States., Vanderah TW; Departments of Pharmacology.; Anesthesiology, and.; Comprehensive Center for Pain and Addiction, College of Medicine, The University of Arizona, Tucson, AZ, United States., Olivera BM; Department of Biology, University of Utah, Salt Lake City, UT, United States., Khanna R; Department of Pharmacology & Therapeutics, College of Medicine, University of Florida, Gainesville, FL, United States.; Pain and Addiction Therapeutics (PATH) Collaboratory, College of Medicine, University of Florida, Gainesville, FL, United States., Patwardhan A; Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, Dallas, TX, United States.; Peter O'Donnell Jr. Brain Institute, Dallas, TX, United States.

Publikováno v: Pain [Pain] 2024 Sep 19. Date of Electronic Publication: 2024 Sep 19.