Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Almudena Hurtado Picó"'
Autor:
TO Lankisch, Almudena Hurtado Picó, Claudia Beutler, Andreas Fischer, Tobias Müller, Torsten Voigtländer, Thomas Berg, Oren Shibolet, Hussain Al–Abadi, Morgane Otten, Wilfried Veltzke Schlieker, Martin Volkmann, Daniel K. Podolsky, Eckart Schott, Angelika Dürr, Andreas Adler, Daniel C. Baumgart, Douglas M. Jefferson, Olaf Guckelberger, Korinna Jöhrens, Mario Anders, Dirk Meyer zum Büschenfelde, Andreas Sturm, Bertram Wiedenmann
Publikováno v:
Gastroenterology. 144:1116-1128
Background & Aims IgG4-related cholangitis is a chronic inflammatory biliary disease that involves different parts of the pancreatobiliary system, but little is known about its mechanisms of pathogenesis. A T-helper (Th) 2 cell cytokine profile predo
Autor:
Stefanie Jost, Amir M. Hossini, Almudena Hurtado Picó, Lothar F. Fecker, Magdalena Schmude, Xiaomin Wang, Jürgen Eberle, Henry Fechner, Constanze Schwarz
Publikováno v:
Experimental Dermatology. 19:e56-e66
The high mortality of melanoma demands the development of new strategies, and gene therapy may be considered provided improvements in efficacy and selectivity. Overexpression of the death ligand CD95L/FasL has been shown in previous studies as highly
Autor:
Henry Fechner, Wolfgang Poller, Almudena Hurtado Picó, Judith Wildner, Xiaomin Wang, Isaac Sipo, Stefan Weger, Sandra Pinkert, Lennart Suckau
Publikováno v:
Journal of Biotechnology. 127:560-574
Tight regulation of oncolytic adenoviruses (oAdV) represents an important requirement for their safe application. Here we describe a new doxycycline (Dox)-dependent oAdV with a bidirectional expression cassette, which drives the expression of the rev
Autor:
Wolfgang Poller, Henry Fechner, Almudena Hurtado Picó, Ulrike Siemetzki, Isaac Sipo, Jürgen Eberle, Xiaomin Wang
Publikováno v:
Molecular Therapy. 11(4):563-577
Restricted replication-competent adenoviruses (RRCAs) using tumor- and tissue-specific promoters (ttsP's) are new tools for cancer gene therapy. In this study we investigated viral and nonviral factors affecting "leakiness" of several ttsP's and thei
Autor:
Daniel S. Pratt, Peter Neuhaus, Andreas Pascher, Claudia Beutler, Bertram Wiedenmann, Tobias Mueller, Thomas Berg, Oren Shibolet, Daniel K. Podolsky, Almudena Hurtado Picó
Publikováno v:
Liver international : official journal of the International Association for the Study of the Liver. 31(10)
Background Pattern recognition receptors (PRRs) orchestrate the innate immune defence in human biliary epithelial cells (BECs). Tight control of PRR signalling provides tolerance to physiological amounts of intestinal endotoxins in human bile to avoi
Autor:
Lothar F, Fecker, Magdalena, Schmude, Stefanie, Jost, Amir M, Hossini, Almudena Hurtado, Picó, Xiaomin, Wang, Constanze, Schwarz, Henry, Fechner, Jürgen, Eberle
Publikováno v:
Experimental dermatology. 19(8)
The high mortality of melanoma demands the development of new strategies, and gene therapy may be considered provided improvements in efficacy and selectivity. Overexpression of the death ligand CD95L/FasL has been shown in previous studies as highly
Autor:
Judith Wildner, Sandra Pinkert, Wolfgang Poller, Henry Fechner, Lennart Suckau, Almudena Hurtado Picó, Isaac Sipo, Stefan Weger
Publikováno v:
Molecular Therapy. 13
Tight regulation of oncolytic adenoviruses (oAdV) represents an important requirement for their safe application. We have developed a new doxycycline (Dox)-dependent oAdV with a bidirectional expression cassette, which drives the expression of the re
Autor:
Jürgen Eberle, Henry Fechner, Almudena Hurtado Picó, Xiaomin Wang, Isaac Sipo, Iver Petersen, Wolfgang Poller, Stefan Weger
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 84(3)
Gene therapy is a new therapeutic approach for the treatment of human cancers. Gene expression systems that can be regulated by drugs have been developed to improve the safety and efficacy of therapeutic transgene delivery. One of the most promising