Výsledky vyhledávání - "Almudena Albillos"

Akademický článek

Monkey adrenal chromaffin cells express α6β4* nicotinic acetylcholine receptors.

Autor: Alicia Hernández-Vivanco, Arik J Hone, Mick L Scadden, Beatriz Carmona-Hidalgo, J Michael McIntosh, Almudena Albillos

Publikováno v: PLoS ONE, Vol 9, Iss 4, p e94142 (2014)

Nicotinic acetylcholine receptors (nAChRs) that contain α6 and β4 subunits have been demonstrated functionally in human adrenal chromaffin cells, rat dorsal root ganglion neurons, and on noradrenergic terminals in the hippocampus of adolescent mice

Externí odkaz: https://doaj.org/article/382a78ac57c8414f9c6b09511bb074ad

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Expression of α3β2β4 nicotinic acetylcholine receptors by rat adrenal chromaffin cells determined using novel conopeptide antagonists

Autor: J. Michael McIntosh, Joanna Gajewiak, Lola Rueda-Ruzafa, Arik J. Hone, Almudena Albillos, Tino Dyhring, Thomas J. Gordon, Sean Christensen

Publikováno v: J Neurochem

Adrenal chromaffin cells release neurotransmitters in response to stress and may be involved in conditions such as post-traumatic stress and anxiety disorders. Neurotransmitter release is triggered, in part, by activation of nicotinic acetylcholine r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97507ef81c745f8f27765b6a68424e95
https://doi.org/10.1111/jnc.14966

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Therapeutic concentrations of varenicline increase exocytotic release of catecholamines from human chromaffin cells in the presence of nicotine

Autor: Amanda Jiménez-Pompa, Sara Sanz-Lázaro, Arik Hone, Lola Rueda-Ruzafa, José Medina-Polo, Carmen González-Enguita, Jesús Blázquez, Cristobal de los Rios, J McIntosh, Almudena Albillos

Background and Purpose: Cardiovascular side effects from varenicline, and a case report of a hypertensive crisis event in a patient with pheochromocytoma being treated with varenicline, have been reported. The goal of the present study was to determi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d22651a0af92d37f38efd910f8cc5100
https://doi.org/10.22541/au.164864792.27829166/v1

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Cross Talk between α7 and α3β4 Nicotinic Receptors Prevents Their Desensitization in Human Chromaffin Cells

Autor: Amanda Jiménez-Pompa, Sara Sanz-Lázaro, Romidan Ewere Omodolor, José Medina-Polo, Carmen González-Enguita, Jesús Blázquez, J. Michael McIntosh, Almudena Albillos

Publikováno v: J Neurosci

The physical interaction and functional cross talk among the different subtypes of neuronal nicotinic acetylcholine receptors (nAChRs) expressed in the various tissues is unknown. Here, we have investigated this issue between the only two nAChRs subt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b81b928997732ad2fdb5ae3bb598fc
https://pubmed.ncbi.nlm.nih.gov/34965978

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The firing frequency of spontaneous action potentials and their corresponding evoked exocytosis are increased in chromaffin cells of CC l 4 ‐induced cirrhotic rats with respect to control rats

Autor: Amanda Jiménez-Pompa, Sarai López‐García, Almudena Albillos, Agustín Albillos, Jose Carlos Caba-González, Beatriz Carmona-Hidalgo, Alicia Hernández-Vivanco, Sara Sanz-Lázaro, M. Ubeda, Leticia Muñoz

Publikováno v: Journal of Neurochemistry. 148:359-372

High catecolamine plasma levels because of sympathetic nervous system over-activity contribute to cirrhosis progression. The aim of this study was to investigate whether chromaffin cells of the adrenal gland might potentiate the deleterious effect ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::62cc2c2d462feca8d866c842a5f47535
https://doi.org/10.1111/jnc.14618

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Therapeutic concentrations of varenicline increases exocytotic release of catecholamines from human and rat adrenal chromaffin cells in the presence of nicotine

Autor: Lola Rueda-Ruzafa, José Medina-Polo, Carmen González-Enguita, Cristóbal de los Ríos, Sara Sanz-Lázaro, Arik J. Hone, Amanda Jiménez-Pompa, Almudena Albillos, Jesús Blázquez, J. Michael McIntosh

Publikováno v: Biblos-e Archivo. Repositorio Institucional de la UAM
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Cardiovascular side effects of varenicline and a case report of a hypertensive crisis in a varenicline-prescribed patient with pheochromocytoma have been reported. The goal of the present study was to determine whether such side effects might derive,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d775eedc3dc0687c9695610b90e2fa2
https://doi.org/10.1016/j.neuropharm.2021.108632

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Human native Cav1 channels in chromaffin cells: contribution to exocytosis and firing of spontaneous action potentials

Autor: Juan Passas, Almudena Albillos, Nuria García-Magro, Cristina de Castro-Guerín, Sergio Alonso y Gregorio, Jose Carlos Caba-González, Alicia Hernández-Vivanco, Beatriz Carmona-Hidalgo, Alberto Perez-Alvarez, Sara Sanz-Lázaro, Jesús Blázquez, Amanda Jiménez-Pompa, Angel Tabernero, Carmen González-Enguita

Publikováno v: European Journal of Pharmacology. 796:115-121

The present study was performed to evaluate the Ca v 1 channel subtypes expressed in human chromaffin cells and the role that these channels play in exocytosis and cell excitability. Here we show that human chromaffin cells obtained from organ donors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::713234482dbde679179784935c7eab14
https://doi.org/10.1016/j.ejphar.2016.12.009

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Therapeutic concentrations of varenicline in the presence of nicotine increase action potential firing in human adrenal chromaffin cells

Autor: Almudena Albillos, Juan Passas, J. Michael McIntosh, Arik J. Hone, Cristina de Castro-Guerín, Lola Rueda-Ruzafa, Jesús Blázquez, Carmen González-Enguita

Publikováno v: Journal of Neurochemistry. 140:37-52

Varenicline is a nicotinic acetylcholine receptor (nAChR) agonist used to treat nicotine addiction but a live debate persists concerning its mechanism of action in reducing nicotine consumption. Although initially reported as α4β2-selective, vareni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9ef8b73a30d1807bc8ec89bbca1602
https://doi.org/10.1111/jnc.13883

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The firing frequency of spontaneous action potentials and their corresponding evoked exocytosis are increased in chromaffin cells of CCl

Autor: Sara, Sanz-Lázaro, Amanda, Jiménez-Pompa, Beatriz, Carmona-Hidalgo, María, Ubeda, Leticia, Muñoz, Jose Carlos, Caba-González, Alicia, Hernández-Vivanco, Sarai, López-García, Agustín, Albillos, Almudena, Albillos

Publikováno v: Journal of neurochemistry. 148(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cc497328aca7ac62afca104b8eb8d5f3
https://pubmed.ncbi.nlm.nih.gov/30347483

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α-Conotoxins Identify the α3β4* Subtype as the Predominant Nicotinic Acetylcholine Receptor Expressed in Human Adrenal Chromaffin Cells

Autor: Paul Whiteaker, J. Michael McIntosh, Layla Azam, Almudena Albillos, Juan Passas, Jon Lindstrom, Linda Lucero, Arik J. Hone, Jesús Blázquez

Publikováno v: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

Ligands that selectively inhibit human α3β2 and α6β2 nicotinic acetylcholine receptor (nAChRs) and not the closely related α3β4 and α6β4 subtypes are lacking. Current α-conotoxins (α-Ctxs) that discriminate among these nAChR subtypes in rat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c52a484cc40a73dfe1ee440f57e796bc
https://doi.org/10.1124/mol.115.100982

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