Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Almohanad A. Alkayyal"'
Autor:
Almohanad A. Alkayyal, Manar Darwish, Reham Ajina, Saleh Y. Alabbas, Mohammed A. Alotaibi, Abeer Alsofyani, Maha Bokhamseen, Maumonah Hakami, Omar A. Albaradie, Abdulaziz M. Moglan, Sharif Hala, Abdullah Faisal Alsahafi, Samer Zakri, Adnan Almuzaini, Khamis Alsharari, Feras Kaboha, Mustafa Y. Taher, Haggag S. Zein, Fayhan Alroqi, Ahmad Bakur Mahmoud
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
The coronavirus disease 2019 (COVID-19) pandemic imposes an urgent and continued need for the development of safe and cost-effective vaccines to induce preventive responses for limiting major outbreaks around the world. To combat severe acute respira
Externí odkaz:
https://doaj.org/article/29f72b40581943c8b85d543f6b8e86ba
Autor:
Rwaa H. Abdulal, Jana S. Malki, Ezdehar Ghazal, Ahdab A. Alsaieedi, Sarah A. Almahboub, Muhammad Yasir Khan, Reem M. Alsulaiman, Mazen M. Ghaith, Turki S. Abujamel, Magdah Ganash, Ahmad Bakur Mahmoud, Almohanad A. Alkayyal, Anwar M. Hashem
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
The use of oncolytic viruses (OVs) in combination with cytokines, such as IL-12, is a promising approach for cancer treatment that addresses the limitations of current standard treatments and traditional cancer immunotherapies. IL-12, a proinflammato
Externí odkaz:
https://doaj.org/article/b9b818696cbd481db8b9dbca51082bad
Autor:
Abdulaziz Molham Moglan, Omar A. Albaradie, Fares Fayez Alsayegh, Hussam Mohsen Alharbi, Yahya Marwan Samman, Mohammed M. Jalal, Nizar H. Saeedi, Ahmad Bakur Mahmoud, Almohanad A. Alkayyal
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundCancer incidence and mortality are increasing rapidly worldwide, necessitating further investigation into developing and optimizing emergent cancer therapies. Oncolytic viruses such as vesicular stomatitis virus encoding interferon β (VSV-
Externí odkaz:
https://doaj.org/article/86c52c55e2df4a1e996727dc23239ea6
Autor:
Sarah Mansouri, Lauren Daniel, Nawal Amhis, Maxime Leveille, Jeanette E. Boudreau, Almohanad A. Alkayyal, Yves Collin, Lee-Hwa Tai
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Pancreatic ductal adenocarcinoma (PDAC) is a high fatality cancer with one of the worst prognoses in solid tumors. Most patients present with late stage, metastatic disease and are not eligible for potentially curative surgery. Despite complete resec
Externí odkaz:
https://doaj.org/article/6f89bf5aaec346779c0d812dda59d59e
Autor:
Seyedeh-Raheleh Niavarani, Guillaume St-Cyr, Lauren Daniel, Christine Lawson, Hugo Giguère, Almohanad A. Alkayyal, Lee-Hwa Tai
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTriple negative breast cancer (TNBC) is the most aggressive and hard-to-treat subtype of breast cancer, affecting 10-20% of all women diagnosed with breast cancer. Surgery, chemotherapy and hormone/Her2 targeted therapies are the cornerst
Externí odkaz:
https://doaj.org/article/82195cfbb3194b929078551add46bff4
Autor:
Almohanad A. Alkayyal, Reham Ajina, Marco Cacciabue, Aaesha A. Alkayyal, Nizar H. Saeedi, Taofik Hussain Alshehry, Feras Kaboha, Mohammed A. Alotaibi, Nada Zaidan, Khalid Shah, Fayhan Alroqi, Ahmad Bakur Mahmoud
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Despite recent advances in the research on oncolytic viruses (OVs), a better understanding of how to enhance their replication is key to improving their therapeutic index. Understanding viral replication is important to improve treatment outcomes bas
Externí odkaz:
https://doaj.org/article/abfe7ad31fc745d88dd4b77df3668a34
Autor:
Guillaume St-Cyr, Daphné Penarroya, Lauren Daniel, Hugo Giguère, Almohanad A. Alkayyal, Lee-Hwa Tai
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
MiRNAs (miRNA, miR) play important functions in the tumor microenvironment (TME) by silencing gene expression through RNA interference. They are involved in regulating both tumor progression and tumor suppression. The pathways involved in miRNA proce
Externí odkaz:
https://doaj.org/article/bdfa51167109479a949ca1ed78f42341
Autor:
Mohammed M. Jalal, Rashid Mir, Abdullah Hamadi, Malik A. Altayar, Imadeldin Elfaki, Jameel Barnawi, Almohanad A. Alkayyal, Mouminah Amr, Jabali Hadeel, Mamdoh S. Moawadh, Basim S. O. Alsaedi, Marwan H. Alhelali, Aadil Yousif
Publikováno v:
Life, Vol 13, Iss 5, p 1200 (2023)
Stroke is a key cerebrovascular disease and important cause of death and disability worldwide, including in the kingdom of Saudi Arabia (KSA). It has a large economic burden and serious socioeconomic impacts on patients, their families and the commun
Externí odkaz:
https://doaj.org/article/09e0edaf7b2a49acb3bad43e1f4b97ed
Autor:
Ahmad Bakur Mahmoud, Reham Ajina, Sarah Aref, Manar Darwish, May Alsayb, Mustafa Taher, Shaker A. AlSharif, Anwar M. Hashem, Almohanad A. Alkayyal
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Glioblastoma multiforme (GBM) is the most common and aggressive malignant brain tumor of the central nervous system and has a very poor prognosis. The current standard of care for patients with GBM involves surgical resection, radiotherapy, and chemo
Externí odkaz:
https://doaj.org/article/9c4379e7569f421fa987f6e97a923bcd
Autor:
Tian-Meng Cui, Muhammad Altaf, Abdu Aldarhami, Abdulrahman S. Bazaid, Nizar H. Saeedi, Almohanad A. Alkayyal, Fahad M. Alshabrmi, Farman Ali, Mohammed Aladhadh, Muhammad Yasir Khan, Ahad Amer Alsaiari, Yue-Rong Ma
Publikováno v:
Molecules, Vol 28, Iss 8, p 3634 (2023)
Overexpression of the thymidine phosphorylase (TP) enzyme induces angiogenesis, which eventually leads to metastasis and tumor growth. The crucial role of TP in cancer development makes it an important target for anticancer drug discovery. Currently,
Externí odkaz:
https://doaj.org/article/b333bdd9062a4ac7a581ec6b78b5c363