Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Almas Rathod"'
Autor:
Marylyn M Addo, Rika Draenert, Almas Rathod, Cori L Verrill, Benjamin T Davis, Rajesh T Gandhi, Gregory K Robbins, Nesli O Basgoz, David R Stone, Daniel E Cohen, Mary N Johnston, Theresa Flynn, Alysse G Wurcel, Eric S Rosenberg, Marcus Altfeld, Bruce D Walker
Publikováno v:
PLoS ONE, Vol 2, Iss 3, p e321 (2007)
CD8+ T cells impact control of viral infections by direct elimination of infected cells and secretion of a number of soluble factors. In HIV-1 infection, persistent HIV-1 specific IFN-gamma+ CD8+ T cell responses are detected in the setting of diseas
Externí odkaz:
https://doaj.org/article/819e2bbb021c4bb98a32c7dff1b61a14
Autor:
Marylyn M. Addo, Xu G. Yu, Philip J. R. Goulder, Bruce D. Walker, Michelle Yu, Eric S. Rosenberg, Marcus Altfeld, Almas Rathod
We have previously shown that Vpu is rarelytargeted by HIV-1-specific cytotoxic T lympho-cytes (CTL). The present report extends thesefindings and describes the characterization of thefirst CTL epitope within HIV-1 Vpu, identified inan individual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f80507c71fa1b03de9c1cc55dc20713
https://doi.org/10.1097/00002030-200205030-00015
https://doi.org/10.1097/00002030-200205030-00015
Autor:
James I. Mullins, Marcus Altfeld, Xu G. Yu, Paul K. Lee, Philip J. R. Goulder, Jason Harlow, Kristin M. O'Sullivan, Eric S. Rosenberg, Christian Brander, Todd M. Allen, Almas Rathod, Mary N. Johnston, Marylyn M. Addo, Bruce D. Walker, Raj Shankarappa, Bette T. Korber
An important first step in the development of an effective human immunodeficiency virus type 1 (HIV-1) vaccine is to understand the correlates of protective immunity in infected persons. An increasing body of evidence points to a central role of HIV-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4e4e6877061794bda65abe0de896731
https://doi.org/10.1128/jvi.77.13.7330-7340.2003
https://doi.org/10.1128/jvi.77.13.7330-7340.2003
Autor:
Bin Li, Todd M. Allen, Brian L. Block, Brett Baker, Christian Brander, Emily Cutrell, Ildiko Toth, Almas Rathod, Alissa C. Rothchild, Arne Schneidewind, Chanson J. Brumme, Nicole Frahm, Alicja Trocha, Mark A. Brockman, Florencia Pereyra, Eric J. Arts, Bruce D. Walker, Toshiyuki Miura, Zabrina L. Brumme, Michael A. Lobritz
Publikováno v:
Journal of Virology. 83:2743-2755
Human immunodeficiency virus type 1 (HIV-1) elite controllers (EC) maintain viremia below the limit of commercial assay detection (240-249 TW10 epitope. The typical escape mutation (T242N) within this epitope diminishes viral replication capacity in
Autor:
Eric S. Rosenberg, Bruce D. Walker, Rachel Rosenberg, Toshiyuki Miura, Peggy Ueda, Marylyn M. Addo, Zhigang Lu, Daniel E. Cohen, Florencia Pereyra, Elizabeth W Mackey, Almas Rathod, Yang Liu, Daniel Kaufmann, Brett Baker, Terri Wrin, Alicja Trocha, Christos J. Petropoulos
Publikováno v:
The Journal of Infectious Diseases. 197:563-571
Spontaneous control of human immunodeficiency virus (HIV) infection has been documented in a minority of HIV-infected individuals. The mechanisms behind this outcome remain largely unknown, and a better understanding of them will likely influence fut
Autor:
Brett Baker, Elizabeth W Mackey, Florencia Pereyra, Michael T. Waring, Mark A. Brockman, Daniel G. Kavanagh, Eric S. Rosenberg, Toshiyuki Miura, Kristin Moss, Ryan Ahern, Anthony D. Kelleher, Baogong Zhu, Sarah Palmer, Gordon J. Freeman, Daniel Kaufmann, Sylvie Le Gall, Almas Rathod, John Zaunders, Alicja Piechocka-Trocha, John M. Coffin, Bruce D. Walker
Publikováno v:
Nature Immunology. 8:1246-1254
In progressive viral infection, antiviral T cell function is impaired by poorly understood mechanisms. Here we report that the inhibitory immunoregulatory receptor CTLA-4 was selectively upregulated in human immunodeficiency virus (HIV)-specific CD4(
Publikováno v:
Journal of Allergy and Clinical Immunology. 118:324-330
A 15-year-old girl with perinatal HIV-1 infection has remained asymptomatic with undetectable plasma HIV-1 viremia for more than 5 years after discontinuing all antiretroviral therapy. Viral sequence analysis of proviral HIV-1 DNA revealed no evident
Autor:
Prinisha Rathnavalu, Senica Chetty, Isobella Honeyborne, Christian Brander, William H. Hildebrand, Rico Buchli, Almas Rathod, Eshia Moodley, Dhanwanthie Ramduth, Cheryl L. Day, Bruce D. Walker, Philip J. R. Goulder, Photini Kiepiela
Publikováno v:
ResearcherID
HIV-specific CTL play a central role in immune control of HIV. The basis for understanding the success or failure of this immune response requires identification of the specific epitopes targeted by CTL. However, in populations most severely affected
Autor:
Marylyn M. Addo, Bianca R. Mothé, Jason Harlow, Alessandro Sette, Eric S. Rosenberg, Elizabeth T. Kalife, Nicole Frahm, Galit Alter, Bruce D. Walker, Laura L. Reyor, John Sidney, Beth Perkins, Todd M. Allen, Xu G. Yu, Philip J. R. Goulder, Loren K. Robinson, Mathias Lichterfeld, Marcus Altfeld, Almas Rathod, Christian Brander
Publikováno v:
Journal of Virology. 79:5000-5005
Human immunodeficiency virus type 1 (HIV-1) mutates to escape immune selection pressure, but there is little evidence of selection mediated through HLA-A2, the dominant class I allele in persons infected with clade B virus. Moreover, HLA-A2-restricte
Autor:
James I. Mullins, Alysse G. Wurcel, Bruce D. Walker, Nicole Frahm, Laura Heath, Marylyn M. Addo, Beth Perkins, Yunzhen Cao, Xu G. Yu, Christopher J. Russell, Giancarlo Tanzi, Shaun C. Geer, Todd M. Allen, Philip J. R. Goulder, Christian Brander, Shan Mei, David Stone, Mark Parta, Feili Wej, Francesco M. Marincola, Almas Rathod, Mathias Lichterfeld, Marcus Altfeld, Daniel E. Cohen
Publikováno v:
AIDS Research and Human Retroviruses. 20:557-564
China is a region of the world with a rapidly spreading HIV-1 epidemic. Studies providing insights into HIV-1 pathogenesis in infected Chinese are urgently needed to support the design and testing of an effective HIV-1 vaccine for this population. HI