Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Alma W. Goldstein"'
Autor:
James Holms, Ruth S. Stanaszek, Alma W. Goldstein, Jerry R. Martin, Momir Cirovic, Alex Michael Nadzan, David Grampovnik, Paulett Johnson, Robert Hallas, Jack Tadanier
Publikováno v:
Carbohydrate Research. 96:185-203
Opening of the aziridine ring of 2-deoxy-1,2-epimino-2- epi -fortimicin B ( 10 ) has been effected with both chloride and azide. The reactions are both stereo- and regiospecific and give 2-chloro-2-deoxyfortimicin B ( 2c ) and 2-azido-2-deoxy-fortimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::660971a80efd21f7deb0e4532faf85d0
https://doi.org/10.1016/s0008-6215(00)81869-8
https://doi.org/10.1016/s0008-6215(00)81869-8
Autor:
Richard S. Egan, Jerry R. Martin, Francis E. Fischer, Ester Hirner, Ruth S. Stanaszek, Alma W. Goldstein, Jack Tadanier
Publikováno v:
The Journal of Organic Chemistry. 39:2495-2501
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d914621e85b02c7b43bb05ffa6de9e
https://doi.org/10.1021/jo00931a006
https://doi.org/10.1021/jo00931a006
Publikováno v:
Tetrahedron. 31:1985-1989
Erythromycin A is slowly metabolized to a new antibiotic, erythromycin E (5), when incubated with fermentations of certain strains of the producing organism Streptomyces erythreus. Erythromycin E contains a novel ortho ester grouping not previously e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcf9153866f92b99a94b2593f67b5e6f
https://doi.org/10.1016/0040-4020(75)80184-0
https://doi.org/10.1016/0040-4020(75)80184-0
Publikováno v:
The Journal of Antibiotics. 33:810-818
The synthesis of 2-deoxyfortimicins A (15) and B (11) and 1-deamino-2-deoxy 2-epi-amino-fortimicins A (18) and B (12) is described. Two routes have been developed for synthesis of the key intermediate 2-O-methanesulfonylfortimicin B (7). One route in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de06dbbd768e8f2a04e374116d47ebc9
https://doi.org/10.7164/antibiotics.33.810
https://doi.org/10.7164/antibiotics.33.810
Autor:
Richard S. Egan, Walter Keller-Schierlein, Jerry R. Martin, Rodger L. Foltz, Sandra L. Mueller, Lester A. Mitscher, Alma W. Goldstein
Publikováno v:
Helvetica Chimica Acta. 59:1886-1894
A further examination of the products from fermentation broths of Streptomyces violaceoniger has yielded small quantities of several lankamycin related antibiotics and metabolites. One of the antibiotics has been characterized as 3″-de-O-methyl-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c2b3903a8b85f2569494f40375a7de
https://doi.org/10.1002/hlca.19760590545
https://doi.org/10.1002/hlca.19760590545
Publikováno v:
The Journal of Organic Chemistry. 43:2351-2356
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88843e6c2f087b29bf4dab7b0fc96ed1
https://doi.org/10.1021/jo00406a010
https://doi.org/10.1021/jo00406a010
Publikováno v:
Tetrahedron. 32:2375-2378
3-O-(2″,6″-Dideoxy-α- l -ribo-hexopyranosyl)erythronolide B (6) and 3-O-(2″,6″-dideoxy-α- l -arabino-hexopyranosyl)erythronolide B (7), aberrant metabolites of erythromycin biosynthesis, have been isolated from the fermentation broth of a b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a19b9206750ff1771fd2984a6eb0033f
https://doi.org/10.1016/0040-4020(76)87017-2
https://doi.org/10.1016/0040-4020(76)87017-2
Publikováno v:
Carbohydrate Research. 85:61-71
Fortimicin A and a number of 4-N-acylfortimicins B, although stable as either the fully protonated hydrochloride or sulfate salts, undergo degradation as the free bases in aqueous solution. Detailed studies with fortimicin A and 4-N-acetylfortimicin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d97080e349be225d486c6f5e9c4b5e55
https://doi.org/10.1016/s0008-6215(00)84564-4
https://doi.org/10.1016/s0008-6215(00)84564-4
Autor:
Arthur C. Sinclair, Jerry R. Martin, Momir Cirovic, Richard S. Egan, Lester A. Mitscher, Alma W. Goldstein, Ruth S. Stanaszek, R. Larry De Vault, Paulette Collum, Earl E. Fager, Jack Tadanier, Sandra L. Mueller
Publikováno v:
The Journal of Antibiotics. 30:552-563
The structures of fortimicins A and B have been determined by PMR, CMR, mass spectra and CD combined with chemical degradations. Both antibiotics are pseudodisaccha-rides and incorporate a novel aminocyclitol, fortamine. Incontrast to the diaminocycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef809dd58b4633215009766e92a5aeab
https://doi.org/10.7164/antibiotics.30.552
https://doi.org/10.7164/antibiotics.30.552
Publikováno v:
Tetrahedron. 29:935-940
8- epi -erythronolide B ( 4 ) has been isolated as a product formed from the acid treatment of erythronolide B ( 3 ). When this compound was fed to a blocked mutant of the erythromycin producing organism, Streptomycetes erythreus (Abbott 2NU153), nea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::387decd1dd247f8aacb3099229a5b2d8
https://doi.org/10.1016/0040-4020(73)80042-0
https://doi.org/10.1016/0040-4020(73)80042-0