Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alma Papusha"'
Publikováno v:
PLoS Genetics, Vol 6, Iss 5, p e1000948 (2010)
The formation of single-stranded DNA (ssDNA) at double-strand break (DSB) ends is essential in repair by homologous recombination and is mediated by DNA helicases and nucleases. Here we estimated the length of ssDNA generated during DSB repair and an
Externí odkaz:
https://doaj.org/article/9bb2e09e45ac4bd3b021e9a9f0cdd6e4
Autor:
Zhenxin Yan, Bo Xia, Guangyu Wang, Kaifu Chen, Nhung Pham, Guang Peng, Grzegorz Ira, Yang Yu, Alma Papusha
Publikováno v:
Nature
Insertions of mobile elements1–4, mitochondrial DNA5 and fragments of nuclear chromosomes6 at DNA double-strand breaks (DSBs) threaten genome integrity and are common in cancer7–9. Insertions of chromosome fragments at V(D)J recombination loci ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e94491db657969c2fb500a35b49cfb4
https://doi.org/10.1038/s41586-018-0769-8
https://doi.org/10.1038/s41586-018-0769-8
Autor:
Hengyao Niu, Yang Yu, Jianjie Zhou, Youngho Kwon, Patrick Sung, Xuewen Pan, Grzegorz Ira, Shuangyi Zhu, Jingjing Wang, Alma Papusha, Dandan Cui, Xuefeng Chen
Publikováno v:
Nucleic Acids Research
DNA double-strand breaks (DSBs) are one of the most cytotoxic types of DNA lesion challenging genome integrity. The activity of cyclin-dependent kinase Cdk1 is essential for DSB repair by homologous recombination and for DNA damage signaling. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4282dec3fb9be8360af4fc3bb5422e3e
https://doi.org/10.1093/nar/gkv1544
https://doi.org/10.1093/nar/gkv1544
Autor:
Jaclyn N. Bonner, Xiaolan Zhao, Barnabas Szakal, Grzegorz Ira, Dana Branzei, Xiaoyu Xue, Yu-Hung Chen, Alma Papusha, Hengyao Niu, Patrick Sung, Dorina Saro, Koyi Choi
Publikováno v:
Genes & Development. 29:1000-1005
Budding yeast Mph1 helicase and its orthologs drive multiple DNA transactions. Elucidating the mechanisms that regulate these motor proteins is central to understanding genome maintenance processes. Here, we show that the conserved histone fold MHF c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb48b65fd4f12154a2114ddcf6f790be
https://doi.org/10.1101/gad.259143.115
https://doi.org/10.1101/gad.259143.115
Autor:
Xiaofeng Zheng, Hengyao Niu, Koyi Choi, Lucy Lu, Alma Papusha, Grzegorz Ira, Xiaoyu Xue, Xiaolan Zhao, Hardeep Kaur, Roberto A. Donnianni, Michael Lichten, Sandeep Kumar, Patrick Sung, Jaclyn N. Bonner
We identified Mte1 (Mph1-associated telomere maintenance protein 1) as a multifunctional regulator of Saccharomyces cerevisiae Mph1, a member of the FANCM family of DNA motor proteins important for DNA replication fork repair and crossover suppressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::040e549d1432e577e57ebf435d4bee88
https://europepmc.org/articles/PMC4803054/
https://europepmc.org/articles/PMC4803054/
Autor:
Dandan Cui, Grzegorz Ira, Xuewen Pan, Jiangwu Tang, Alma Papusha, Xiaotian Zhang, Chia Dwo Chu, Xuefeng Chen, Kaifu Chen
Publikováno v:
Nature. 489:576-580
Chromosomal double-strand breaks (DSBs) are resected by 5' nucleases to form 3' single-stranded DNA substrates for binding by homologous recombination and DNA damage checkpoint proteins. Two redundant pathways of extensive resection have been describ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e49a4d11aea39be8a3bd40adef08194a
https://doi.org/10.1038/nature11355
https://doi.org/10.1038/nature11355
Autor:
Eun Yong Shim, Woo Hyun Chung, Hengyao Niu, Patrick Sung, Alma Papusha, Xuefeng Chen, Sang Eun Lee, Grzegorz Ira, Zhu Zhu
Publikováno v:
Nature structural & molecular biology
DNA recombination pathways are regulated by the cell cycle to coordinate with replication. Cyclin-dependent kinase (Cdk1) promotes efficient 5' strand resection at DNA double-strand breaks (DSBs), the initial step of homologous recombination and dama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a18efa96208a1f98d156d636e15509
https://doi.org/10.1038/nsmb.2105
https://doi.org/10.1038/nsmb.2105
Publikováno v:
PLoS Genetics, Vol 6, Iss 5, p e1000948 (2010)
PLoS Genetics
PLoS Genetics
The formation of single-stranded DNA (ssDNA) at double-strand break (DSB) ends is essential in repair by homologous recombination and is mediated by DNA helicases and nucleases. Here we estimated the length of ssDNA generated during DSB repair and an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7ee87001db0f96c746f42074e091f0
http://europepmc.org/articles/PMC2869328?pdf=render
http://europepmc.org/articles/PMC2869328?pdf=render
Autor:
Giacomo De Piccoli, Andrés Aguilera, Alma Papusha, Kyungjae Myung, Pranav Ullal, Felipe Cortés-Ledesma, Luis Aragón, Ji-Young Hwang, Jordi Torres-Rosell, James E. Haber, Farokh Dotiwala, Sarah Farmer, Andrés Clemente-Blanco, Felip Vilella-Mitjana, Félix Machín, Audrey Ceschia, Alexandra McAleenan, Xiaolan Zhao, Beatriz Leitao, Stefan Uhle, Violeta Cordon-Preciado, Debra A. Bressan, Adam Jarmuz, Gregory Ira
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
idUS. Depósito de Investigación de la Universidad de Sevilla
DNA double-strand breaks (DSB) can arise during DNA replication, or after exposure to DNA-damaging agents, and their correct repair is fundamental for cell survival and genomic stability. Here, we show that the Smc5–Smc6 complex is recruited to DSB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fa9c18edda23b508a525edafab5e28b
https://europepmc.org/articles/PMC4493748/
https://europepmc.org/articles/PMC4493748/
Autor:
Xuefeng Chen, Hengyao Niu, Yang Yu, Jingjing Wang, Shuangyi Zhu, Jianjie Zhou, Alma Papusha, Dandan Cui, Xuewen Pan, Youngho Kwon, Patrick Sung, Ira, Grzegorz
Publikováno v:
Nucleic Acids Research; 4/7/2016, Vol. 44 Issue 6, p2742-2753, 12p