Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Allyson L, Anding"'
Autor:
Margaret Clagett-Dame, Robert W. Curley, Derek W. Barnett, Jason S. Chapman, Allyson L. Anding
Supplementary Figure 2 from The Unhydrolyzable Fenretinide Analogue 4-Hydroxybenzylretinone Induces the Proapoptotic Genes GADD153 (CHOP) and Bcl-2–Binding Component 3 (PUMA) and Apoptosis that Is Caspase- Dependent and Independent of the Retinoic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b48acf69f3be76c4640a8d424e54171
https://doi.org/10.1158/0008-5472.22367547.v1
https://doi.org/10.1158/0008-5472.22367547.v1
Autor:
Margaret Clagett-Dame, Robert W. Curley, Derek W. Barnett, Jason S. Chapman, Allyson L. Anding
The synthetic retinoid N-(4-hydroxyphenyl)retinamide (4-HPR) induces apoptosis in a variety of cell lines and has shown promise as an anticancer agent both in vitro and in vivo. The clinical dose of 4-HPR, however, is limited by residual-associated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bce3d90a21d69d6e7a313f2cc4973f0
https://doi.org/10.1158/0008-5472.c.6495594.v1
https://doi.org/10.1158/0008-5472.c.6495594.v1
Autor:
Margaret Clagett-Dame, Robert W. Curley, Derek W. Barnett, Jason S. Chapman, Allyson L. Anding
Supplementary Figure 1 from The Unhydrolyzable Fenretinide Analogue 4-Hydroxybenzylretinone Induces the Proapoptotic Genes GADD153 (CHOP) and Bcl-2–Binding Component 3 (PUMA) and Apoptosis that Is Caspase- Dependent and Independent of the Retinoic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b8500b0a9c7b1a427e10698929af76
https://doi.org/10.1158/0008-5472.22367550
https://doi.org/10.1158/0008-5472.22367550
Autor:
Dragan Maric, Gil Kanfer, William A. Prinz, Hetal V. Shah, Eric H. Baehrecke, Heather Baldwin, Richard J. Youle, Chunxin Wang, Norbert Brüggemann, Allyson L. Anding, Antonio Velayos-Baeza, Marija Dulovic-Mahlow
Publikováno v:
The Journal of Cell Biology
The VPS13 proteins (VPS13A–D) are thought to mediate lipid transport between organelles and are linked to distinct neurological disorders in humans. Baldwin et al. found that, in addition to known involvement in mitochondrial morphology, VPS13D is
Autor:
James D. Jones, Margaret Clagett-Dame, Robert W. Curley, Allyson L. Anding, Michael A. Newton
Publikováno v:
Anticancer research. 38(8)
Background/aim N-(4-hydroxyphenyl)retinamide (4-HPR) is a synthetic retinoid, less toxic than the parent all-trans retinoic acid (RA). Unlike RA, 4-HPR induces apoptosis in tumor cells. Because 4-HPR can hydrolyze to liberate RA, a potent human terat
Autor:
Richard J. Youle, Tsun-Kai Chang, Chunxin Wang, Christine M. Powers, Allyson L. Anding, Danielle A. Sliter, Kay Hofmann, Eric H. Baehrecke
Publikováno v:
Current biology : CB. 28(2)
The clearance of mitochondria by autophagy, mitophagy, is important for cell and organism health [1], and known to be regulated by ubiquitin. During Drosophila intestine development, cells undergo a dramatic reduction in cell size and clearance of mi
Autor:
Allyson L. Anding, Eric H. Baehrecke
The selective clearance of organelles by autophagy is critical for the regulation of cellular homeostasis in organisms from yeast to humans. Removal of damaged organelles clears the cell of potentially toxic byproducts and enables reuse of organelle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c720478c8914737a20c65ffa32031a3b
https://europepmc.org/articles/PMC5395098/
https://europepmc.org/articles/PMC5395098/
Autor:
Allyson L. Anding, Eric H. Baehrecke
Publikováno v:
Cell Death & Differentiation. 22:457-464
Autophagy is a catabolic process used to deliver cellular material to the lysosome for degradation. The core Vps34/class III phosphatidylinositol 3-kinase (PI3K) complex, consisting of Atg6, Vps15, and Vps34, is highly conserved throughout evolution,
Autor:
Robert W. Curley, Laura A. Stonerock, Serena M. Mershon, Allyson L. Anding, Jason S. Chapman, Margaret Clagett-Dame
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:836-840
Using solid phase-assisted synthesis and purification, a 49 member library of analogs of the mammary tumor chemopreventive retinoid N-(4-hydroxyphenyl)retinamide (4-HPR) has been prepared. After prescreening for growth inhibitory activity in human ma
Autor:
Allyson L, Anding, Eric H, Baehrecke
Publikováno v:
Current topics in developmental biology. 114
Macroautophagy (hereafter referred to as autophagy) is a process used by the cell to deliver cytoplasmic components to the lysosome for degradation. Autophagy is most often associated with cell survival, as it provides cells with molecular building b