Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Allyson G. McLoed"'
Autor:
Allyson G. McLoed, Taylor P. Sherrill, Dong-Sheng Cheng, Wei Han, Jamie A. Saxon, Linda A. Gleaves, Pingsheng Wu, Vasiliy V. Polosukhin, Michael Karin, Fiona E. Yull, Georgios T. Stathopoulos, Vassilis Georgoulias, Rinat Zaynagetdinov, Timothy S. Blackwell
Publikováno v:
Cell Reports, Vol 16, Iss 1, Pp 120-132 (2016)
Although epithelial NF-κB signaling is important for lung carcinogenesis, NF-κB inhibitors are ineffective for cancer treatment. To explain this paradox, we studied mice with genetic deletion of IKKβ in myeloid cells and found enhanced tumorigenes
Externí odkaz:
https://doaj.org/article/f58ff440a1344da388aafc8cddd5f332
Autor:
Timothy S. Blackwell, Georgios T. Stathopoulos, Fiona E. Yull, Barbara Fingleton, R. Stokes Peebles, Daniel Dulek, Linda Connelly, Arun C. Habermann, Jamie A. Saxon, Allyson G. McLoed, Linda A. Gleaves, Taylor P. Sherrill, Rinat Zaynagetdinov
Figure S2. Deficiency in IL-5 does not affect infiltration of lungs with T and B lymphocytes and NK cells during initial stages of metastatic load of LLC cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f629ace44083a1b9a05698a550cda3b
https://doi.org/10.1158/0008-5472.22407179.v1
https://doi.org/10.1158/0008-5472.22407179.v1
Autor:
Jamie A. Saxon, Wei Han, Taylor P. Sherrill, Harikrishna Tanjore, Allyson G. McLoed, Fiona E. Yull, Timothy S. Blackwell, Linda A. Gleaves, Vasiliy V. Polosukhin, Bradley W. Richmond, Dong-Sheng Cheng, Whitney Barham
Publikováno v:
The Journal of Immunology. 196:1891-1899
Although numerous studies have demonstrated a critical role for canonical NF-κB signaling in inflammation and disease, the function of the noncanonical NF-κB pathway remains ill-defined. In lung tissue from patients with acute respiratory distress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e467ec3d659b8949fa0fbc64cdc9d769
https://doi.org/10.4049/jimmunol.1501555
https://doi.org/10.4049/jimmunol.1501555
Autor:
Timothy S. Blackwell, Allyson G. McLoed, Wei Han, Rinat Zaynagetdinov, Linda A. Gleaves, Lisa R. Young, Peter M. Gulleman, Jamie A. Saxon, Taylor P. Sherrill, Pierre Hunt, Harikrishna Tanjore
Publikováno v:
Oncotarget
// Rinat Zaynagetdinov 1 , Taylor P. Sherrill 1 , Linda A. Gleaves 1 , Pierre Hunt 1 , Wei Han 1 , Allyson G. McLoed 2 , Jamie A. Saxon 2 , Harikrishna Tanjore 1 , Peter M. Gulleman 4 , Lisa R. Young 1, 4 , Timothy S. Blackwell 1, 2, 3 1 Department o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0134b701ce6434c4eeaa725fe8a14d3f
http://europepmc.org/articles/PMC4868699
http://europepmc.org/articles/PMC4868699
Autor:
Fiona E. Yull, Zhongming Zhao, Allyson G. McLoed, Linda A. Gleaves, Timothy S. Blackwell, Jamie A. Saxon, Vasiliy V. Polosukhin, Hui Yu, Georgios T. Stathopoulos, Pierre P. Massion
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Sci. Rep. 8:6078 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Sci. Rep. 8:6078 (2018)
While many studies have demonstrated that canonical NF-κB signaling is a central pathway in lung tumorigenesis, the role of non-canonical NF-κB signaling in lung cancer remains undefined. We observed frequent nuclear accumulation of the non-canonic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca0a5a4babf0ce4375fce5b11f6acf7
https://doi.org/10.1038/s41598-018-24488-8
https://doi.org/10.1038/s41598-018-24488-8
Autor:
Linda A. Gleaves, Barbara Fingleton, R. Stokes Peebles, Georgios T. Stathopoulos, Daniel E. Dulek, Rinat Zaynagetdinov, Allyson G. McLoed, Arun C. Habermann, Timothy S. Blackwell, Fiona E. Yull, Jamie A. Saxon, Linda Connelly, Taylor P. Sherrill
Publikováno v:
Cancer Research. 75:1624-1634
Although the lung is the most common metastatic site for cancer cells, biologic mechanisms regulating lung metastasis are not fully understood. Using heterotopic and intravenous injection models of lung metastasis in mice, we found that IL5, a cytoki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fec8f19c115ac16ed6dfd2b30f7c4b04
https://doi.org/10.1158/0008-5472.can-14-2379
https://doi.org/10.1158/0008-5472.can-14-2379
Autor:
Lawrence S. Prince, Timothy S. Blackwell, Weisong Zhou, Georgios T. Stathopoulos, Taylor P. Sherrill, Linda Connelly, Dong-Sheng Cheng, Fiona E. Yull, Jamie A. Ausborn, Barbara Fingleton, Rinat Zaynagetdinov, Allyson G. McLoed, Peebles Rs, Vasiliy V. Polosukhin
Publikováno v:
Oncogene
The mechanisms by which chronic inflammatory lung diseases, particularly chronic obstructive pulmonary disease, confer enhanced risk for lung cancer are not well-defined. To investigate whether nuclear factor (NF)-κB, a key mediator of immune and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1571bfc1681c99a1a9494cf085934a33
https://doi.org/10.1038/onc.2011.480
https://doi.org/10.1038/onc.2011.480
Autor:
Ann Richmond, Linda A. Gleaves, Jamie A. Saxon, Fiona E. Yull, Allyson G. McLoed, Jiqing Sai, Vasiliy V. Polosukhin, Timothy S. Blackwell, Whitney Barham, Rinat Zaynagetdinov, Raphael P. Hunt, Peter Gulleman, Lisa R. Young, Taylor P. Sherrill, Dong-Sheng Cheng
Publikováno v:
Oncoimmunology. 5(6)
Several studies have demonstrated that NF-κB activation is common in lung cancer; however, the mechanistic links between NF-κB signaling and tumorigenesis remain to be fully elucidated. We investigated the function of NF-κB signaling in epidermal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb600768f66efc4e4458351a8bfaffe
https://pubmed.ncbi.nlm.nih.gov/27471643
https://pubmed.ncbi.nlm.nih.gov/27471643
Autor:
Fiona E. Yull, Wei Han, Jamie A. Ausborn, Timothy S. Blackwell, Rinat Zaynagetdinov, Frank B. McMahon, Taylor P. Sherrill, Vasiliy V. Polosukhin, Amber L. Degryse, Linda A. Gleaves, Allyson G. McLoed, Georgios T. Stathopoulos
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 187(11)
Macrophages, have established roles in tumor growth and metastasis, but information about their role in lung tumor promotion is limited. To assess the role of macrophages in lung tumorigenesis, we developed a method of minimally-invasive, long-term m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b5e919a7ef0272819486ad67dd91e2
https://pubmed.ncbi.nlm.nih.gov/22048774
https://pubmed.ncbi.nlm.nih.gov/22048774
Autor:
Rinat Zaynagetdinov, Taylor P. Sherrill, Fiona E. Yull, Allyson G. McLoed, Timothy S. Blackwell
Publikováno v:
Cancer Research. 74:3667-3667
The transcription factor Nuclear Factor κB (NF-κB) is a master regulator of inflammation, and its activation is associated with tumorigenesis in a variety of cancers. Our group and others have shown that NF-κB signaling in lung epithelial cells is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4efd631f6aeaa2e0d2793fb9a63727a0
https://doi.org/10.1158/1538-7445.am2014-3667
https://doi.org/10.1158/1538-7445.am2014-3667