Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Allyson G, Hindle"'
Autor:
Hyun Ji Noh, Jason Turner-Maier, S. Anne Schulberg, Michael L. Fitzgerald, Jeremy Johnson, Kaitlin N. Allen, Luis A. Hückstädt, Annabelle J. Batten, Jessica Alfoldi, Daniel P. Costa, Elinor K. Karlsson, Warren M. Zapol, Emmanuel S. Buys, Kerstin Lindblad-Toh, Allyson G. Hindle
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
The Antarctic Weddell inhabits one of the most extreme environments on Earth. Comparative genomics with close relatives reveals the specific genetic adaptations for cardiovascular and fat metabolism that enable it to thrive.
Externí odkaz:
https://doaj.org/article/8e512fac09d54dce8a64472c5044d4ff
Autor:
Eizo Marutani, Masanobu Morita, Shuichi Hirai, Shinichi Kai, Robert M. H. Grange, Yusuke Miyazaki, Fumiaki Nagashima, Lisa Traeger, Aurora Magliocca, Tomoaki Ida, Tetsuro Matsunaga, Daniel R. Flicker, Benjamin Corman, Naohiro Mori, Yumiko Yamazaki, Annabelle Batten, Rebecca Li, Tomohiro Tanaka, Takamitsu Ikeda, Akito Nakagawa, Dmitriy N. Atochin, Hideshi Ihara, Benjamin A. Olenchock, Xinggui Shen, Motohiro Nishida, Kenjiro Hanaoka, Christopher G. Kevil, Ming Xian, Donald B. Bloch, Takaaki Akaike, Allyson G. Hindle, Hozumi Motohashi, Fumito Ichinose
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
The brain is sensitive to oxygen deprivation. Here, the authors show in experimental animals that sensitivity to hypoxia is inversely related to the level of sulfide:quinone oxidoreductast (SQOR) and the capacity to catabolize sulfide in the brain.
Externí odkaz:
https://doaj.org/article/e9e4bccfec79480492fb63f03e33bd26
Autor:
Markus Horning, Russel D. Andrews, Amanda M. Bishop, Peter L. Boveng, Daniel P. Costa, Daniel E. Crocker, Martin Haulena, Mark Hindell, Allyson G. Hindle, Rachel R. Holser, Sascha K. Hooker, Luis A. Hückstädt, Shawn Johnson, Mary-Anne Lea, Birgitte I. McDonald, Clive R. McMahon, Patrick W. Robinson, Renae L. Sattler, Courtney R. Shuert, Sheanna M. Steingass, Dave Thompson, Pamela A. Tuomi, Cassondra L. Williams, Jamie N. Womble
Publikováno v:
Animal Biotelemetry, Vol 7, Iss 1, Pp 1-17 (2019)
Abstract Pinnipeds spend large portions of their lives at sea, submerged, or hauled-out on land, often on remote off-shore islands. This fundamentally limits access by researchers to critical parts of pinniped life history and has spurred the develop
Externí odkaz:
https://doaj.org/article/26a0ab64f6a040a68843ecf3256a82ce
Publikováno v:
Comprehensive Physiology
Continuous physiological measurements collected in field settings are essential to understand baseline, free-ranging physiology, physiological range and variability, and the physiological responses of organisms to disturbances. This article presents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::675267380d30f12c6fb1947d3c61d64c
https://doi.org/10.1002/cphy.c200005
https://doi.org/10.1002/cphy.c200005
Autor:
Rebecca Li, Benjamin A. Olenchock, Shinichi Kai, Tomoaki Ida, Yumiko Yamazaki, Hozumi Motohashi, Naohiro Mori, Masanobu Morita, Xinggui Shen, Daniel Flicker, Christopher G. Kevil, Annabelle Batten, Dmitriy N. Atochin, Lisa Traeger, Benjamin Corman, Yusuke Miyazaki, Eizo Marutani, Fumiaki Nagashima, Motohiro Nishida, Kenjiro Hanaoka, Robert M. H. Grange, Aurora Magliocca, Takaaki Akaike, Daniel Bloch, Tetsuro Matsunaga, Takamitsu Ikeda, Shuichi Hirai, Tomohiro Tanaka, Akito Nakagawa, Fumito Ichinose, Ming Xian, Allyson G. Hindle, Hideshi Ihara
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Nature Communications
The mammalian brain is highly vulnerable to oxygen deprivation, yet the mechanism underlying the brain’s sensitivity to hypoxia is incompletely understood. Hypoxia induces accumulation of hydrogen sulfide, a gas that inhibits mitochondrial respirat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b245bdec1dc4755f55c0addef3654b49
https://doaj.org/article/e9e4bccfec79480492fb63f03e33bd26
https://doaj.org/article/e9e4bccfec79480492fb63f03e33bd26
Autor:
Rajeev Malhotra, Bryn Reinstadler, Aranya Bagchi, Daniel Bloch, Hardik Shah, Fumito Ichinose, Robert M. H. Grange, Eizo Marutani, Gregory R. Wojtkiewicz, Vamsi K. Mootha, Marissa K. Cooper, Yusuke Miyazaki, Grigorij Schleifer, Allyson G. Hindle, Akito Nakagawa, Warren M. Zapol, Olga Goldberger, Rohit Sharma, Annabelle Batten
Publikováno v:
Molecular Genetics and Metabolism. 133:83-93
Leigh syndrome is a severe mitochondrial neurodegenerative disease with no effective treatment. In the Ndufs4−/− mouse model of Leigh syndrome, continuously breathing 11% O2 (hypoxia) prevents neurodegeneration and leads to a dramatic extension (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b8dfb0c48990bb2740cda981f0aec86
https://doi.org/10.1016/j.ymgme.2021.03.005
https://doi.org/10.1016/j.ymgme.2021.03.005
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d55694c8e8879c33af5b2dbcbdb4662f
https://doi.org/10.1096/fasebj.2022.36.s1.r3227
https://doi.org/10.1096/fasebj.2022.36.s1.r3227
Autor:
Lauren A. Cooley, Daniel P. Costa, Shawn M. Hannah, Allyson G. Hindle, Rachel R. Holser, Markus Horning, Holger Klinck, Paul J. Ponganis, Cassondra L. Williams, Birgitte I. McDonald
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ea961d8fc63c35267d6483c3bd0668e
https://doi.org/10.1096/fasebj.2022.36.s1.r5726
https://doi.org/10.1096/fasebj.2022.36.s1.r5726
Autor:
Shawn M. Hannah, Cassondra L. Williams, Allyson G. Hindle, Lauren A. Cooley, Paul J. Ponganis, Markus Horning, Holger Klinck, Daniel P. Costa, Birgitte I. McDonald
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c8d92d30daa592ba8c68ca03929e13e
https://doi.org/10.1096/fasebj.2022.36.s1.r5937
https://doi.org/10.1096/fasebj.2022.36.s1.r5937
Publikováno v:
Comp Biochem Physiol B Biochem Mol Biol
Mechanistic evaluations of processes that underlie organism-level physiology often require reductionist approaches. Dermal fibroblasts offer one such approach. These cells are easily obtained from minimally invasive skin biopsy, making them appropria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6baab07579e8e7fb771c5834fa1f70
https://europepmc.org/articles/PMC9215708/
https://europepmc.org/articles/PMC9215708/
